Trials / Completed
CompletedNCT06135792
The Effect of Arginine on Biofilm Composition, Architecture and Metabolism
The Effect of Arginine on Biofilm Composition, Architecture and Metabolism in Caries-active Patients: a Split-mouth in Situ Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- University of Aarhus · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Arginine is an adjunct to oral health care that has the potential to modulate the composition and activity of the microbial community of dental biofilms towards a health-related status without harmful effects for the resident oral microbiota. The aim of the study is to investigate the effects of arginine treatment compared to placebo on the composition, metabolism, and microarchitecture of biofilms grown in situ in the oral cavity of caries-active participants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Arginine | See arm description |
| OTHER | Placebo | See arm description |
Timeline
- Start date
- 2023-10-19
- Primary completion
- 2024-02-13
- Completion
- 2024-02-13
- First posted
- 2023-11-18
- Last updated
- 2024-12-27
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT06135792. Inclusion in this directory is not an endorsement.