Trials / Not Yet Recruiting

Not Yet RecruitingNCT06889363

Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial

Status: Not Yet Recruiting
Phase: Phase 2
Study type: Interventional
Enrollment: 50 (estimated)

Sponsor: Cairo University · Academic / Other
Sex: All
Age: 20 Years – 40 Years
Healthy volunteers: Not accepted

Summary

The aim of this study is the clinical and radiographic evaluation of (Platelet-Rich Fibrin (PRF) versus Mineral Trioxide Aggregate (MTA) in indirect pulp capping when used with deep carious molars over 1 year follow up.

Detailed description

-PICOTS : P: Asymptomatic deep carious molars. I: Indirect pulp capping using PRF. C: Indirect pulp capping using MTA. O: Outcome name Measuring device Measuring unit Primary outcome: clinical findings : Pulp sensibility using cold test (Sharma A et al., 2020). Secondary outcome: Radiographic findings :Dentin bridge measurement in mm using digital radiographic ruler Digital Periapical using paralleling technique (Sharma A et al., 2020). T: T0: Baseline T1: 3 months T2: 6 months T3: 12 months S: Randomized clinical trial. \- Research question: Will PRF provide comparable clinical and radiographic outcomes to MTA in indirect pulp capping when used in deep carious molars?

Conditions

Interventions

Type	Name	Description
DRUG	MTA	The indirect pulp capping will be applied using MTA using an MTA carrier, then glass ionomer will be applied, then composite restoration above
BIOLOGICAL	PRF	The indirect pulp capping will be applied using PRF on a membrane, then glass ionomer will be applied , then composite restoration above

Timeline

Start date: 2025-06-01
Primary completion: 2026-09-01
Completion: 2026-09-01
First posted: 2025-03-21
Last updated: 2025-03-21

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT06889363. Inclusion in this directory is not an endorsement.