NCT03731780

Personalized Caries Management Versus Standard of Care for Preventing Incidence of Caries in Young Egyptian Adults

Personalized Caries Management Versus Standard of Care for Preventing Incidence of Caries in Young Egyptian Adults: A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 81 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

Basic standard of care emphasis only tooth brushing and flossing without addressing individual pathological factors. For this reason, randomized controlled clinical trials on personalized caries management are needed to be able to compare the effectiveness of personalized caries management to basic standard of care. This is especially true in high caries risk populations and more so for young adults who stand to benefit the most from working towards a caries free adulthood.

Detailed description

Aim of the study: is to conduct an RCT to compare the effectiveness of a new personalized caries-control treatment protocol with standard caries treatment protocol for reducing caries incidence in high caries risk patients Hypothesis: This project will be designed to test the null hypothesis that there is no significant difference between the new personalized caries-control treatment protocol and existing standard caries treatment protocol, and to test the alternative hypothesis that the new personalized treatment protocol will be superior to the standard preventive measures Primary objective: is to measure the incidence of new caries lesions

Conditions

• Dental Caries

Interventions

Type	Name	Description
OTHER	Personalized Treatment	Targeting individual caries risk factors
OTHER	Chlorhexidine and Remineralization	chlorhexidine mouth wash and remineralizing agent
OTHER	Control	Control is standard preventive measures (tooth brushing, fluoride tooth paste, interdental cleaning)

Timeline

• Start date: 2018-12-01
• Primary completion: 2020-03-01
• Completion: 2020-07-01
• First posted: 2018-11-06
• Last updated: 2018-11-07

Locations

1 site across 1 country: Egypt