NCT06517927

Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 142 (estimated)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 12 Years – 36 Years
• Healthy volunteers: Not accepted

Summary

To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development. The aims of this study are : * Assess the caries risk in childhood cancer survivors compared with a control group. * Assess the dental development defects risk in childhood cancer survivors compared with a control group.

Detailed description

This will be an international study comparing the Childhood Cancer Survivors (CCS) and a control group. A questionnaire will be provided to the patients to gather information. A standard of care dental examination will then take place in a dental office in the Cliniques Universitaires Saint-Luc. We also collect medical data to complete the files.

Conditions

• Chemotherapy Effect
• Dental Caries
• Malocclusion
• Childhood Cancer
• Tooth Defect

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Clinical and radiographic dental examination	complete clinical oral examination + intra-oral and panoramic x-rays

Timeline

• Start date: 2024-05-03
• Primary completion: 2026-05-03
• Completion: 2026-05-03
• First posted: 2024-07-24
• Last updated: 2024-11-19

Locations

1 site across 1 country: Belgium