| Not Yet Recruiting | Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults NCT06564207 | Inova Health Care Services | Phase 2 |
| Not Yet Recruiting | Assessment of Acute Respiratory Distress in Children Presenting to the Emergency Department: Clinical, Epidemi NCT07149389 | Assiut University | — |
| Suspended | Vascular ARDS Recruitment After Inhaled Nitric Oxide NCT05801224 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | To Evaluate the Safety and Potential Therapeutic Activity of JadiCell™, an Investigational Umbilical Cord-Deri NCT07479043 | Breathe Biologics, Inc. | Phase 3 |
| Withdrawn | Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS NCT04452097 | Baylx Inc. | Phase 1 / Phase 2 |
| Not Yet Recruiting | Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia NCT07492888 | ImmunityBio, Inc. | Phase 2 |
| Not Yet Recruiting | Corticosteroids in Hyperinflammatory Phenotype of Critical Illness NCT07511582 | Bin Du | Phase 2 |
| Not Yet Recruiting | EIT- Guided Lung Recruitment in pARDS NCT07402174 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Not Yet Recruiting | Correlation Between EIT-based Pulse Wave Method for Pulmonary Perfusion Monitoring and Pulmonary Artery Cathet NCT07385963 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Recruiting | Practices of Prone Positioning Ventilation in Patients With Moderate-to-Severe ARDS in Intensive Care Units: A NCT07284888 | Southeast University, China | — |
| Recruiting | Validation and Precision Treatment of Inflammatory Subphenotypes in Acute Respiratory Distress Syndrome: A Mul NCT07289711 | Southeast University, China | — |
| Recruiting | A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+ NCT07326215 | Vantive Health LLC | N/A |
| Recruiting | The Physiological Effect of RCexp on Ventilation/Perfusion Distribution NCT06919484 | Southeast University, China | — |
| Recruiting | JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab NCT06701656 | PPD Development, LP | Phase 2 |
| Recruiting | Extended Prone Positioning for Intubated ARDS NCT07126964 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | High-Frequency Oscillation Ventilation Versus Conventional Mechanical Ventilation in Very Preterm Infants With NCT03736707 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Recruiting | The ARISE Study - Use of Vertical Positioning NCT07025421 | University of Alabama at Birmingham | N/A |
| Recruiting | Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients NCT06513949 | Implicit Bioscience | Phase 2 |
| Not Yet Recruiting | A Validation Study on a Prognostic Prediction Model for Respiratory Tract Infections NCT07109310 | Peking Union Medical College Hospital | — |
| Recruiting | JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab NCT06701682 | PPD Development, LP | Phase 2 |
| Recruiting | JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record) NCT06703073 | PPD Development, LP | Phase 2 |
| Recruiting | JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart NCT06701669 | PPD Development, LP | Phase 2 |
| Recruiting | "Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory D NCT06814340 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Recruiting | A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Res NCT07413978 | Changchun Tuohua Pharmaceutical Co., Ltd. | Phase 1 / Phase 2 |
| Recruiting | Effect of Continuous Prolonged Prone Position Versus Intermittent Daily Prone Position in ARDS NCT06854627 | Pontificia Universidad Catolica de Chile | N/A |
| Recruiting | Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial) NCT04208126 | University Hospital Tuebingen | N/A |
| Completed | Invasive Ventilation for Neonates With Acute Respiratory Distress Syndrome(ARDS) NCT03591796 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Not Yet Recruiting | MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients NCT06308926 | MedRegen LLC | Phase 2 |
| Recruiting | Ultra-Protective Lung Ventilation With Extracorporeal CO2 Removal for Moderate ARDS NCT04903262 | University of Bologna | N/A |
| Recruiting | The Role of Cxcr4Hi neutrOPhils in InflueNza NCT06254313 | University Hospital, Bordeaux | — |
| Not Yet Recruiting | Effects of End-inspiratory Pause on Ventilation NCT06692634 | Clinica las Condes, Chile | N/A |
| Unknown | Thorathic Fluid Content as an Early Predictor of Weaning From Mechanical Ventilation in Acute Respiratory Dist NCT06233448 | Tanta University | — |
| Recruiting | Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in Mechanical Ventilatio NCT06662630 | Shanghai Zhongshan Hospital | N/A |
| Unknown | Physiological Study of Prone Position in Acute Respiratory Failure Syndrome NCT06061796 | Assistance Publique - Hôpitaux de Paris | N/A |
| Not Yet Recruiting | Efficacy and Safety of LEAF-4L6715 for Acute Respiratory Distress Syndrome NCT06640777 | LEAF4Life, Inc. | Phase 3 |
| Recruiting | EIT Assessment of Overdistension in ARDS Patients in Prone Position NCT06536543 | University Hospital, Bordeaux | — |
| Recruiting | Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS) NCT05947955 | BioAegis Therapeutics Inc. | Phase 2 |
| Recruiting | Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome NCT06690801 | Children's Hospital Los Angeles | — |
| Withdrawn | Assessment of Occult Lung Stress During Lung Protective Mechanical Ventilation NCT05675696 | NYU Langone Health | N/A |
| Recruiting | By Assessing the Continuous Respiratory Physiological Changes Through Prone Position, Determine the Optimal Du NCT06827184 | National Taiwan University Hospital | — |
| Not Yet Recruiting | Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients NCT06206473 | University Hospital, Toulouse | N/A |
| Recruiting | Early Diagnosis of ARDS in Mechanically Ventilated Patient Using LUS Score in Comparison With CT NCT06971042 | Tanta University | — |
| Recruiting | A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome NCT06496997 | Fayoum University | Phase 2 / Phase 3 |
| Not Yet Recruiting | Clinical Study on the Safety and Preliminary Efficacy of hUC-MSCs Intravenous Infusion Therapy for ARDS NCT06505941 | Southeast University, China | Phase 1 / Phase 2 |
| Withdrawn | Stability of Driving Pressure Changes During "Best Positive End Expiratory Pressure (PEEP)" Trial NCT05958862 | University of Alabama at Birmingham | — |
| Recruiting | Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome NCT06066502 | Beth Israel Deaconess Medical Center | Phase 3 |
| Not Yet Recruiting | Multiple Study of Electroaccpuncture in ARDS NCT06278675 | Nanjing University of Traditional Chinese Medicine | N/A |
| Recruiting | Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS NCT06387823 | Peking Union Medical College Hospital | N/A |
| Recruiting | Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive ve NCT06357780 | Başakşehir Çam & Sakura City Hospital | N/A |
| Completed | Comparing Mechanical Power in Different Inspiratory Times NCT06413472 | Başakşehir Çam & Sakura City Hospital | — |
| Recruiting | Effect of PP in Patients With Ultra-low VT NCT06215209 | Southeast University, China | — |
| Unknown | Inhaled Nitric Oxide for ARDS-related Pulmonary Hypertension NCT06249633 | Yuri Matusov | EARLY_Phase 1 |
| Recruiting | Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS NCT06188195 | The Second Affiliated Hospital of Chongqing Medical University | N/A |
| Recruiting | The Role of Elastic Power in Predicting the Severity and Mortality in Adult Patients With ARDS Due to Pneumoni NCT06477861 | Benha University | — |
| Unknown | Mesenchymal Stem Cells for The Treatment of Acute Respiratory Distress Syndrome (ARDS) NCT04347967 | Meridigen Biotech Co., Ltd. | Phase 1 |
| Unknown | The Burden of Acute Respiratory Failure in Chinese ICUs: a National Cohort Study NCT06213779 | Southeast University, China | — |
| Unknown | Safety and Preliminary Clinical Activity of Itolizumab in ARDS NCT05978544 | Biotech Pharmaceutical Co., Ltd. | Phase 1 |
| Completed | Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With ARDS by EIT NCT06181539 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Recruiting | Mesenchymal Stem Cells (MSCs) and Conditioned Medium Mesenchymal Stem Cells as Adjuvant Therapy for Sepsis NCT07439848 | PT. Prodia Stem Cell Indonesia | Phase 1 / Phase 2 |
| Completed | To Evaluate The Safety and Initial Efficacy of STSA-1002 Injection in Patients With Acute Respiratory Distress NCT06038916 | Staidson (Beijing) Biopharmaceuticals Co., Ltd | Phase 1 / Phase 2 |
| Active Not Recruiting | Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndr NCT04870125 | Brigham and Women's Hospital | Phase 1 |
| Recruiting | Prone Positioning and Abdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Brea NCT05826847 | University of Chile | N/A |
| Not Yet Recruiting | Safety, Tolerability, and Efficacy of MatriPlax in Subjects With Acute Respiratory Distress Syndrome NCT05886985 | BioSpring Medical Co., Ltd | Phase 1 |
| Recruiting | Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS) NCT06001645 | Università Vita-Salute San Raffaele | — |
| Recruiting | Comparaison of Two Prone Position Techniques on Occurence of Pressure Sores in ICU NCT05894291 | University Hospital, Tours | N/A |
| Recruiting | Reverse Trigger Phenotypification and Response to Ventilatory Adjustments NCT06148467 | Hospital Civil de Guadalajara | — |
| Unknown | Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome NCT06014138 | Guy's and St Thomas' NHS Foundation Trust | Phase 2 / Phase 3 |
| Completed | The Value of Serum MicroRNA-21-5p and LncRNAgadd7 Expression Levels in Predicting the Severity and Prognosis o NCT06825754 | Shao Yuekai | — |
| Recruiting | Association Between the Level of EV-TF and the Occurence of Pulmonary Embolism in Patients With ARDS NCT05855317 | Assistance Publique Hopitaux De Marseille | — |
| Unknown | Epidemiological Characteristics and Prediction System of Acute Respiratory Distress Syndrome NCT06069466 | China-Japan Friendship Hospital | — |
| Recruiting | Fluid Responsiveness Prediction During Prone Position NCT05898269 | Hospices Civils de Lyon | N/A |
| Recruiting | Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO NCT06062212 | Beijing Chao Yang Hospital | — |
| Unknown | Paramedical Protocol for Ventilation in Acute Respiratory Distress Syndrome NCT06039215 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement NCT06051292 | Dr. Behcet Uz Children's Hospital | N/A |
| Recruiting | FCV vs PCV in Moderate to Severe ARDS NCT06051188 | Erasmus Medical Center | N/A |
| Unknown | Prone Position in infantS/Children With Acute Respiratory Distress Syndrome NCT06020404 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Unknown | The Use of Exosomes for the Treatment of Acute Respiratory Distress Syndrome or Novel Coronavirus Pneumonia Ca NCT04798716 | AVEM HealthCare | Phase 1 / Phase 2 |
| Recruiting | Physiological Studies in the Prone Position in Patients With ARDS NCT06586736 | West China Hospital | — |
| Unknown | Effect of Nebulized and Intravenous Hypertonic Saline 3% on the Management of Patients With Acute Respiratory NCT06226402 | Tanta University | N/A |
| Recruiting | Nalbuphine in ARDS Patients After Surgery NCT06037330 | Hairong Chen | Phase 4 |
| Recruiting | Imaging Biomarkers to Stratify the Risk of Barotrauma in ARDS NCT05816954 | Università Vita-Salute San Raffaele | — |
| Not Yet Recruiting | Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells in Patients With Acute Respiratory Distress Synd NCT05983627 | Asia Cell Therapeutics (Shanghai) Co., Ltd. | Phase 1 |
| Unknown | Electroacupuncture Modulates SPMs Metabolism and Respiratory Symptoms in Patients With Sepsis Complicating ARD NCT06006325 | Tianjin Nankai Hospital | N/A |
| Unknown | Prone Position With Different Types of Cushions in Patients With ARDS NCT06184490 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Prediction of Duration of Mechanical Ventilation in ARDS NCT05993377 | Dr. Negrin University Hospital | — |
| Recruiting | Inhaled Sevoflurane for ARDS Prevention NCT05849779 | University Hospital, Clermont-Ferrand | Phase 3 |
| Completed | Effect of APRV vs. LTV on Right Heart Function in ARDS Patients: a Single-center Randomized Controlled Study NCT05922631 | XiaoJing Zou,MD | N/A |
| Unknown | Pressure Opening With Electrical Impedance Tomography NCT05825534 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-can NCT05750576 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | The ICU LIBERATION Study NCT05844579 | Japanese Society for Early Mobilization | — |
| Recruiting | The Effect of Erythropoietin on Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome NCT05857891 | Second Affiliated Hospital of Wenzhou Medical University | N/A |
| Active Not Recruiting | Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis NCT05930418 | St. Jude Children's Research Hospital | N/A |
| Unknown | Efficacy and Safety of Anakinra in Acute Respiratory Distress Syndrome NCT05914454 | Azienda Sanitaria-Universitaria Integrata di Udine | Phase 2 |
| Recruiting | Early PP Monitored by EIT in Patients With ARDS NCT05822869 | Beijing Chao Yang Hospital | N/A |
| Unknown | Transbronchial Lung Cryobiopsy in Undiagnosed Acute Respiratory Failure NCT05754866 | China-Japan Friendship Hospital | N/A |
| Completed | Improvement of ARDS Ventilation-perfusion Matching by Prone Positioning Assessed by EIT NCT05765760 | Beijing Chao Yang Hospital | — |
| Unknown | Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV NCT05768230 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Phase 2 / Phase 3 |
| Recruiting | Influence of NEP Inhibition on Vascular Leak and Inflammation (NEPi-INFLAMMATION) NCT05600062 | Queen Mary University of London | N/A |
| Completed | The Acute Respiratory Intervention StudiEs in Africa (ARISE-AFRICA) Study NCT04693403 | Makerere University | N/A |
| Completed | Effect of Continuous Anterior Chest Compression on Ventilation/Perfusion Ratio and Hemodynamics NCT06699017 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome NCT06013319 | Zhiming Jiang | Phase 3 |
| Unknown | Neutrophil Elastase Inhibitor in Treatment of ARDS Patients With Mechanical Ventilation Caused by Sepsis NCT05672472 | The First Hospital of Jilin University | N/A |
| Unknown | Effect of APRV and LTV on Lung Ventilation and Perfusion in Patients With Moderate-to-severe ARDS NCT05767125 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | N/A |
| Recruiting | Nosocomial Infections in ECMO Patients NCT05566665 | Policlinico Hospital | — |
| Completed | Transpulmonary Pressure in Right Ventricle Protection of ARDS NCT05629832 | Beijing Chao Yang Hospital | N/A |
| Recruiting | Inflammation During ECMO Therapy and ECMO Weaning NCT05640635 | University Hospital Tuebingen | N/A |
| Recruiting | Personalized Tidal Volume in ARDS (VT4HEMOD) NCT05406570 | Hospices Civils de Lyon | N/A |
| Recruiting | Incidence and Evolution of Heart-lung Interaction in Acute Respiratory Distress Syndrome NCT07450846 | Bicetre Hospital | — |
| Terminated | Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia NCT05531149 | Biotest | Phase 3 |
| Withdrawn | CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 NCT04378244 | Aveni Foundation | Phase 1 / Phase 2 |
| Terminated | Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain In NCT05464277 | Evangelismos Hospital | N/A |
| Unknown | Recruitment Maneuver After Bronchoalveolar Lavage in ARDS Patients NCT05372731 | Southeast University, China | N/A |
| Completed | Predicting ICU Mortality in ARDS Patients NCT05611177 | Dr. Negrin University Hospital | — |
| Unknown | 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDS NCT05514483 | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | Phase 4 |
| Unknown | Ventilator-induced Right Ventricular Injury During EIT-based PEEP Titration in Patients With ARDS NCT05583461 | University of Padova | N/A |
| Unknown | European Registry for Hemadsorption in Sepsis With the Seraph Filter NCT05608096 | Croatian Society for Organ Support | — |
| Withdrawn | Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Infla NCT04490486 | Joshua M Hare | Phase 1 |
| Withdrawn | Respiratory COVID-19: A Randomized, Sham-Controlled Study NCT05166915 | Aytu BioPharma, Inc. | N/A |
| Unknown | Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome NCT05658692 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 4 |
| Completed | Open Suction vs. Closed Suction in ARDS NCT05537974 | Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital | N/A |
| Recruiting | Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress NCT05535543 | Istanbul University - Cerrahpasa | — |
| Completed | PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia NCT05650957 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Unknown | Lessening Organ Dysfunction With VITamin C in Septic ARDS NCT04404387 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Prevention of Skin Damage in the Patient in Prone Position: Development of Education Interventions Based on a NCT05238870 | University Ghent | — |
| Withdrawn | Glucocorticoid Therapy for Acute Respiratory Distress Syndrome NCT05401812 | National Taiwan University Hospital | Phase 2 |
| Recruiting | Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) NCT05354141 | Direct Biologics, LLC | Phase 3 |
| Recruiting | CytOSorb TreatMent Of Critically Ill PatientS Registry NCT05146336 | CytoSorbents, Inc | — |
| Recruiting | Safety of Low PEEP Maneuvers During ARDS Management NCT05922969 | Centre Hospitalier Universitaire, Amiens | — |
| Unknown | Evaluation of the Efficiency and Complications of the Consequtive Proning in Covid -19 ICU NCT05387356 | Kecioren Education and Training Hospital | — |
| Unknown | Potential for Inhaled Nitric Oxide and Ventilation-Perfusion Mismatch by Electrical Impedance Tomography in th NCT04776408 | Far Eastern Memorial Hospital | N/A |
| Recruiting | Treatment of ARDS With Sivelestat Sodium NCT04909697 | Sichuan Provincial People's Hospital | Phase 4 |
| Suspended | Inhalational (Sevoflurane) Versus Intravenous (Propofol) Sedation in Adults With a Moderate Form of ARDS NCT05259631 | Negovsky Reanimatology Research Institute | Phase 3 |
| Unknown | Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19 NCT05248243 | Ramos Mejía Hospital | — |
| Recruiting | Avalanche Phenomenon During Airways Opening in Acute Respiratory Distress Syndrome NCT05224323 | Poitiers University Hospital | — |
| Unknown | Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers - ICU Patients NCT05365854 | University Hospital, Clermont-Ferrand | N/A |
| Withdrawn | ART-3 Pilot - Driving Pressure Limited Ventilation for Patients Without ARDS (ART3pilot) NCT02376647 | Hospital do Coracao | N/A |
| Terminated | Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery NCT05258617 | Ward Photonics LLC | — |
| Unknown | Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes NCT05451342 | Peking Union Medical College Hospital | — |
| Unknown | Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease NCT04412395 | National Research Centre, Egypt | Phase 2 |
| Recruiting | Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDS NCT05474196 | Bicetre Hospital | — |
| Unknown | Pronation During Veno-venous Extra Corporeal Membrane Oxygenation NCT05198986 | University Magna Graecia | — |
| Completed | Effects of Blood Pulsatility on Von Willebrand Factor During ECCO2R NCT05079009 | Assistance Publique - Hôpitaux de Paris | N/A |
| Withdrawn | Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of CT303 in Patients With ARDS NCT05238532 | GC Cell Corporation | Phase 1 |
| Completed | Thoracic Fluid Content by Bioimpedance-based Starling System NCT05676723 | Bicetre Hospital | — |
| Recruiting | Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. NCT05123755 | Vasomune Therapeutics, Inc. | Phase 2 |
| Recruiting | EndotyPIng PreHospitAl de Novo Acute hYpoxemic Respiratory Failure NCT05150483 | Evangelismos Hospital | — |
| Recruiting | Early Verticalization of the Patient With Acute Respiratory Distress Syndrome: Assessment of Feasibility and S NCT04472260 | Centre Hospitalier Régional d'Orléans | N/A |
| Withdrawn | A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and NCT04953052 | Exvastat Ltd. | Phase 2 |
| Completed | Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery NCT04291508 | Massachusetts General Hospital | Phase 2 |
| Completed | Treatment of COVID-19 Positive/Negative Bangladeshi Adults With Severe Respiratory Complaints by a Locally Mad NCT05158842 | International Centre for Diarrhoeal Disease Research, Bangladesh | N/A |
| Terminated | Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumoni NCT04972318 | Hospital do Coracao | N/A |
| Unknown | Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome NCT05056090 | University Hospital, Grenoble | N/A |
| Withdrawn | Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Non-COVID-19 Acute Respiratory Distress Syndrom NCT04909879 | Sorrento Therapeutics, Inc. | Phase 2 |
| Completed | Phrenic Nerve Stimulation-Induced Lung ReAeration Trial NCT04844892 | Lungpacer Medical Inc. | N/A |
| Completed | Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress NCT04935697 | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | N/A |
| Unknown | A Study to Evaluate the Safety and Effect of STC314 Injection Continuous Infusion in Subjects With Acute Respi NCT05000671 | Grand Medical Pty Ltd. | Phase 1 |
| Unknown | The Mechanism of lncRNA NEAT1 in Alleviating Acute Respiratory Distress Syndrome Through miR-27b Regulated Nrf NCT04937855 | Beijing Anzhen Hospital | — |
| Unknown | DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia NCT04836780 | Hospital Universitario Infanta Leonor | Phase 3 |
| Recruiting | Pilot Clinical Study of NOA-001 for ARDS (Acute Respiratory Distress Syndrome) NCT04804943 | Toray Industries, Inc | N/A |
| Completed | PEEP and Spontaneous Breathing During ARDS NCT04241874 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Unknown | Cerebral Bleeding in COVID-19 ARDS Patients on Veno-venous ECMO NCT04853953 | University of Zurich | — |
| Completed | Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial NCT04865107 | Ottawa Hospital Research Institute | Phase 2 |
| Completed | Plasma Biomarkers of Cardiopulmonary Bypass Induced Acute Respiratory Distress Syndrome (CPB-ARDS) NCT04696172 | Huazhong University of Science and Technology | — |
| Completed | Prospective Electroencephalography Evaluation of Sedation in COVID-19 NCT04815109 | Goethe University | — |
| Completed | Ultrasonic Weaning Criteria in Prolonged Ventilation NCT05794867 | King Abdul Aziz Specialist Hospital | — |
| Active Not Recruiting | Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning NCT04744298 | University of Calgary | N/A |
| Unknown | Tolerability and Efficacy of RJX in Patients With COVID-19 NCT04708340 | Reven Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Terminated | Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients NCT04794088 | Dr. Jurjan Aman | Phase 2 |
| Withdrawn | Safety of T Regulatory Cell Therapy in Subjects With COVID-19 Induced Acute Respiratory Distress Syndrome NCT04737161 | Stanford University | Phase 1 |
| Terminated | Study of Descartes-30 in Acute Respiratory Distress Syndrome NCT04524962 | Cartesian Therapeutics | Phase 1 |
| Completed | Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study NCT04663802 | University of Pennsylvania | N/A |
| Completed | Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease) NCT04345601 | Baylor College of Medicine | Phase 1 / Phase 2 |
| Unknown | Prevention and Treatment With Hydroxychloroquine + Azithromycin of Acute Respiratory Syndrome Induced by COVID NCT04954040 | Maimónides Biomedical Research Institute of Córdoba | Phase 2 |
| Recruiting | ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND) NCT05388708 | University of Michigan | — |
| Unknown | Assessment of Cardiac Output in Patients With ARDS Implanted With Venous-venous ECMO. NCT05164484 | Assistance Publique - Hôpitaux de Paris | N/A |
| Terminated | Risk Factors for COVID-19 Mortality NCT04786808 | Teodoro Marcianò | — |
| Completed | Ventilation-Perfusion Matching in Early-stage Prone Position Ventilation NCT05816928 | Peking Union Medical College Hospital | — |
| Terminated | Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (C NCT04502433 | Chiesi Farmaceutici S.p.A. | Phase 2 |
| Unknown | Organ-substituting Technologies in the Treatment of Heart and Pulmonary Failure NCT05042622 | National Research Center for Cardiac Surgery, Kazakhstan | N/A |
| Completed | Effect of Prone Positionning in Non Intubated Patients NCT06517745 | Mongi Slim Hospital | — |
| Unknown | Effects of Extravascular Lung Water on Prone Position Efficacy in Patients With ARDS NCT04635267 | Bicetre Hospital | — |
| Recruiting | Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(N NCT04777760 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | — |
| Terminated | A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-1 NCT04537806 | Sage Therapeutics | Phase 3 |
| Completed | Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 NCT04659109 | Acticor Biotech | Phase 2 |
| Completed | A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COV NCT04640194 | Boehringer Ingelheim | Phase 2 / Phase 3 |
| Unknown | RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study NCT04659460 | Unity Health Toronto | N/A |
| Recruiting | A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in A NCT03549910 | West China Hospital | N/A |
| Unknown | Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19 NCT04760821 | Ministry of Health, Brazil | Phase 2 |
| Completed | Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO) NCT04660448 | Fundación para la Investigación Biosanitaria del Principado de Asturias | — |
| Unknown | Assessment of Microcirculation Alteration With Both Sublingual Microcirculation and Near-infrared Spectroscopy NCT05180409 | Chang Gung Memorial Hospital | — |
| Completed | A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS NCT04602104 | Ruijin Hospital | Phase 1 / Phase 2 |
| Terminated | Study to Find the Highest Safe Dose of Soluble Guanylate Cyclase (sGC) Activator, BAY 1211163 Administered as NCT04609943 | Bayer | Phase 1 |
| Recruiting | Reduction of Blood Recirculation in Veno-Venous ECMO NCT04754854 | Charite University, Berlin, Germany | — |
| Terminated | SILtuximab in Viral ARds (SILVAR) Study NCT04616586 | RECORDATI GROUP | Phase 3 |
| Unknown | Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19 NCT05228717 | Olive View-UCLA Education & Research Institute | — |
| Unknown | CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals NCT04402879 | University of Calgary | N/A |
| Unknown | Quantitative Computed Tomography for Mortality Risk Stratification in ARDS NCT06113276 | Hospices Civils de Lyon | — |
| Completed | Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform NCT04663776 | Boston Children's Hospital | — |
| Completed | Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Vent NCT04603755 | Direction Centrale du Service de Santé des Armées | — |
| Terminated | Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Acute Respirato NCT04565249 | Pliant Therapeutics, Inc. | Phase 2 |
| Withdrawn | Impact of Tissue Plasminogen Activator (tPA) Treatment for an Atypical Acute Respiratory Distress Syndrome (CO NCT04453371 | Negovsky Reanimatology Research Institute | Phase 3 |
| Completed | LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID- NCT04402957 | Arch Biopartners Inc. | Phase 2 |
| Unknown | COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patien NCT04524156 | Erasme University Hospital | N/A |
| Enrolling By Invitation | The Medical Management in Patients Exposed to Weapons of Mass Destruction NCT05026645 | St. Justine's Hospital | — |
| Completed | Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS) NCT04530604 | Gregory Yanik | Phase 1 |
| Completed | Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2 NCT04998253 | Unidad Temporal COVID-19 en Centro Citibanamex | EARLY_Phase 1 |
| Completed | Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure NCT04451291 | University Health Network, Toronto | N/A |
| Completed | Survival Rates and Longterm Outcomes After COVID-19 NCT04601090 | Oslo University Hospital | — |
| Completed | Double-blind, Randomized, Controlled Clinical Trial to Assess Efficacy of MSC in Patients With COVID-19 ARDS NCT04615429 | Cristina Avendaño Solá | Phase 2 |
| Completed | Zofin (Organicell Flow) for Patients With COVID-19 NCT04384445 | ZEO ScientifiX, Inc. | Phase 1 / Phase 2 |
| Completed | Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure (C-ARF) NCT04534569 | NMC Specialty Hospital | — |
| Completed | Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome NCT04818164 | Istanbul University - Cerrahpasa | — |
| Completed | Virtual Reality Distraction Technique to Improve Chest Burns With Acute Respiratory Distress Syndrome NCT05692557 | Prince Sattam Bin Abdulaziz University | N/A |
| Completed | The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying NCT04537351 | Cynata Therapeutics Limited | Phase 1 |
| Completed | Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Pati NCT04478071 | The University of Texas Health Science Center, Houston | Phase 2 |
| Enrolling By Invitation | Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System NCT04369599 | Emory University | N/A |
| Unknown | Helmet vs Face Mask in Patients With Acute Respiratory Distress Syndrome NCT04507802 | Hamad Medical Corporation | N/A |
| Unknown | The Effect of Positive End-Expiratory Pressure on Functional Residual Capacity During Mechanical Ventilation NCT03511651 | Capital Medical University | N/A |
| Completed | Blood Volume Assessment in COVID-19 and Bacterial Sepsis NCT04517695 | NYU Langone Health | — |
| Recruiting | Prediction of Inspiratory Effort Response to High PEEP in Patients Recovering From ARDS NCT04524091 | Sanatorio Anchorena San Martin | — |
| Completed | Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19) NCT04466098 | Masonic Cancer Center, University of Minnesota | Phase 2 |
| Completed | Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 NCT04973488 | Novacescu Alexandru | N/A |
| Withdrawn | Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite NCT04401527 | Hope Pharmaceuticals | Phase 2 |
| Terminated | Safety and Effectiveness Assessment of the MakAir Artificial Ventilator NCT04475185 | Nantes University Hospital | N/A |
| Terminated | Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Impr NCT04433546 | PhaseBio Pharmaceuticals Inc. | Phase 2 |
| Terminated | This Study Collects Information on the Safety of Inhaled Pegylated Adrenomedullin (PEG-ADM), How the Drug is T NCT04417036 | Bayer | Phase 2 |
| Completed | Prone Position and Renal Resistive Index NCT04286490 | University Hospital, Grenoble | N/A |
| Completed | Airway Pressure Release Ventilation for Moderate-to-severe Acute Respiratory Distress Syndrome NCT04156438 | Saskatchewan Health Authority - Regina Area | N/A |
| Completed | Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Dat NCT04383730 | University Hospital, Clermont-Ferrand | — |
| Completed | Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome NCT04184674 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Study of Biomarkers in Patients of Sepsis Complicated With Acute Respiratory Distress Syndrome (ARDS) NCT04552821 | Tianjin Nankai Hospital | — |
| Unknown | Impact of Respiratory Virus in Critically Ill Patients With Acute Respiratory Failure NCT04411368 | Seoul St. Mary's Hospital | — |
| Unknown | Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Dis NCT04408326 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | Predictors of Severe COVID-19 Outcomes NCT04388813 | Verily Life Sciences LLC | — |
| Completed | A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 NCT04402060 | Apellis Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Completed | Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrom and With or W NCT04386720 | University Hospital, Bordeaux | — |
| Completed | Human Ab Response & immunoMONItoring of COVID-19 Patients NCT04373200 | Rennes University Hospital | N/A |
| Unknown | Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress S NCT04380935 | Indonesia University | Phase 2 / Phase 3 |
| Completed | Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome NCT04400032 | Ottawa Hospital Research Institute | Phase 1 / Phase 2 |
| Completed | Effectiveness of Convalescent Immune Plasma Therapy NCT04442958 | Bagcilar Training and Research Hospital | N/A |
| Completed | Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection NCT04357730 | Denver Health and Hospital Authority | Phase 2 |
| Unknown | Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS NCT04391140 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Terminated | Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia NCT04369469 | Alexion Pharmaceuticals, Inc. | Phase 3 |
| Completed | One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 NCT04457505 | Consorcio Centro de Investigación Biomédica en Red (CIBER) | — |
| Completed | SEvoflurane for Sedation in ARds NCT04235608 | University Hospital, Clermont-Ferrand | Phase 3 |
| Completed | Prono Position and Mechanical Power NCT04369105 | Sanatorio Anchorena San Martin | — |
| Completed | Efficacy and Safety of Itolizumab in COVID-19 Complications NCT04475588 | Biocon Limited | Phase 2 |
| Terminated | MSCs in COVID-19 ARDS NCT04371393 | Icahn School of Medicine at Mount Sinai | Phase 3 |
| Terminated | Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 NCT04365985 | Corewell Health East | Phase 2 |
| Unknown | Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Pa NCT04385004 | University Hospital, Strasbourg, France | — |
| Completed | Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19) NCT04358939 | University Hospital, Tours | N/A |
| Completed | Knowledge, Attitude and Practice of Dental Students About COVID-19 NCT04449081 | Melaka Manipal Medical College | — |
| Completed | Use of UC-MSCs for COVID-19 Patients NCT04355728 | Camillo Ricordi | Phase 1 / Phase 2 |
| Completed | Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS) NCT04402840 | West Virginia University | N/A |
| Terminated | Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNA NCT04355364 | Fondation Ophtalmologique Adolphe de Rothschild | Phase 3 |
| Unknown | Pilot Study on Cytokine Filtration in COVID-19 ARDS NCT04361526 | Manuel Castellà | N/A |
| Terminated | Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVI NCT04335786 | Radboud University Medical Center | Phase 4 |
| Terminated | Sedation With Sevoflurane Versus Propofol in Patients With Acute Respiratory Distress Syndrome Caused by COVID NCT04359862 | Fundación para la Investigación del Hospital Clínico de Valencia | Phase 4 |
| Completed | Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia NCT04349618 | Hospices Civils de Lyon | N/A |
| Unknown | Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients NCT04358627 | Hospital Clinic of Barcelona | — |
| Completed | A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to NCT04378920 | Institut de cancérologie Strasbourg Europe | Phase 1 / Phase 2 |
| Unknown | Biomarkers, Genomics, Physiology in Critically Ill and ECMO Patients NCT04669444 | University of California, San Diego | N/A |
| Terminated | COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III NCT04327401 | Hospital Sirio-Libanes | Phase 3 |
| Completed | Losartan for Patients With COVID-19 Requiring Hospitalization NCT04312009 | University of Minnesota | Phase 2 |
| Unknown | Maneuver for Evaluating the Potential Recruitability of the Pulmonary Parenchyme in Patients With ARDS NCT04387669 | University Hospital, Caen | — |
| Completed | Polyvalent Immunoglobulin in COVID-19 Related ARds NCT04350580 | Centre Hospitalier St Anne | Phase 3 |
| Recruiting | Macrophage Programing in Acute Lung Injury: MiniBAL NCT05767671 | William Janssen, MD | N/A |
| Completed | Construction of a Composite Clinical-echo Score Predictive of a Risk of Short-term Aggravation of Respiratory NCT04370249 | Nantes University Hospital | — |
| Completed | Losartan for Patients With COVID-19 Not Requiring Hospitalization NCT04311177 | University of Minnesota | Phase 2 |
| Completed | Pre-exposure Prophylaxis for SARS-Coronavirus-2 NCT04328467 | University of Minnesota | Phase 3 |
| Unknown | Impact of Angiotensin II Receptor Blockers Treatment in Patients With COVID 19 (COVID-ARA2) NCT04337190 | University Hospital, Angers | — |
| Completed | Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS NCT04325906 | Rush University Medical Center | N/A |
| Completed | Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19) NCT04376905 | University Hospital, Montpellier | — |
| Completed | Pulmonary and Ventilatory Effects of Bed Verticalization in Patients With Acute Respiratory Distress Syndrome NCT04371016 | University Hospital, Clermont-Ferrand | N/A |
| Terminated | Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19 NCT04305457 | Massachusetts General Hospital | Phase 2 |
| Completed | Decision Support System to Evaluate VENTilation in ARDS NCT04115709 | Imperial College London | N/A |
| Unknown | Description of Respiratory Mechanics in Patients With SARS-CoV-2 Associated ARDS NCT04350710 | University Hospital, Angers | — |
| Completed | The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective NCT05677165 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Completed | Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2 NCT04308668 | University of Minnesota | Phase 3 |
| Completed | Physical Rehabilitation in ICU in ARDS Patients With COVID-19 NCT04435080 | Koç University | — |
| Completed | Clinical Features of COVID-19 Patients NCT04815304 | San Salvatore Hospital of L'Aquila | — |
| Completed | Hemodynamic Characteristics of Patients With SARS-CoV-2 NCT04337983 | Bicetre Hospital | — |
| Completed | Mechanisms for Organ Dysfunction in Covid-19 NCT04316884 | Uppsala University | — |
| Active Not Recruiting | Pulmonary Fibrosis During Severe COVID-19 Pneumonia NCT04987528 | Hôpital Européen Marseille | — |
| Completed | Different PEEP Settings of COVID-19 Induced ARDS NCT04359251 | Southeast University, China | N/A |
| Completed | Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome NCT04383678 | Helsinki University Central Hospital | — |
| Completed | Impact of Decreasing Respiratory Rate on Lung Injury Biomarkers in ARDS Patients NCT04641897 | Pontificia Universidad Catolica de Chile | N/A |
| Terminated | Sevoflurane PharmacokInetics in ARDS NCT04023305 | University Hospital, Clermont-Ferrand | N/A |
| Unknown | Complications Related to Transpulmonary Thermodilution NCT04319965 | Bicetre Hospital | — |
| Terminated | Inhaled Steroids for the Treatment of Early Pediatric Acute Respiratory Distress Syndrome NCT04064684 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | suPAR Michigan M2C2 Heterogeneity Validation Cohort Study NCT07466524 | ViroGates A/S | — |
| Completed | Impact of the Depth of Neuromuscular Blockade on Respiratory Mechanics in Moderate to Severe ARDS Patients NCT05697666 | Centre Hospitalier de Saint-Brieuc | — |
| Unknown | Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS NCT04331613 | Chinese Academy of Sciences | Phase 1 / Phase 2 |
| Unknown | Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS NCT04352725 | Centre Hospitalier Intercommunal Aix-Pertuis | N/A |
| Terminated | Safety and Efficacy of Intravenous Wharton's Jelly Derived Mesenchymal Stem Cells in Acute Respiratory Distres NCT04390152 | BioXcellerator | Phase 1 / Phase 2 |
| Completed | Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome NCT04113434 | Children's Hospital of Philadelphia | — |
| Completed | The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumon NCT04325685 | Northern State Medical University | N/A |
| Completed | Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome NCT04289194 | Histocell, S.L. | Phase 1 / Phase 2 |
| Completed | TelePORT Pilot Study NCT03926533 | Vanderbilt University | N/A |
| Unknown | Pulmonary Microbiota and ARDS Mortality NCT04133558 | University of Bordeaux | — |