NCT06919484

The Physiological Effect of RCexp on Ventilation/Perfusion Distribution

The Physiological Effect of RCexp on Ventilation/Perfusion Distribution in Patients With ARDS

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Southeast University, China · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

With the exception of setting the positive end-expiratory pressure (PEEP), the expiratory phase is commonly overlooked during MV. The expiratory time constant (RCexp) plays an important role in understanding the mechanical properties of the respiratory system in patients receiving mechanical ventilation. However, it is unclear that the effect of expiratory time constant on the ventilation and perfusion distribution.

Detailed description

With the exception of setting the positive end-expiratory pressure (PEEP), the expiratory phase is commonly overlooked during MV. The expiratory time constant (RCexp) plays an important role in understanding the mechanical properties of the respiratory system in patients receiving mechanical ventilation. However, it is unclear that the effect of expiratory time constant on the ventilation and perfusion distribution.

Conditions

• Acute Respiratory Distress Syndrome
• Mechanical Ventilation

Interventions

Type	Name	Description
OTHER	RCexp	patients received different RCexp

Timeline

• Start date: 2025-11-30
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2025-04-09
• Last updated: 2025-11-26

Locations

1 site across 1 country: China