Trials / Conditions / Mechanical Ventilation

Mechanical Ventilation

377 registered clinical trials studyying Mechanical Ventilation — 98 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Mode of Ventilation During Critical Illness at Multiple Centers NCT07313956	Vanderbilt University Medical Center	N/A
Not Yet Recruiting	Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children Wi NCT07486167	Charite University, Berlin, Germany	Phase 1 / Phase 2
Not Yet Recruiting	Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patien NCT07484828	Laval University	—
Not Yet Recruiting	Microbiome-guided Prophylaxis to Reduce Ventilator-Associated Pneumonia in Intensive Care Units: A Pilot Rando NCT07463339	University of Calgary	Phase 2
Not Yet Recruiting	Amnioinfusion's Protective Effects on Respiratory and Longitudinal Pediatric Outcomes After Intrapartum Thick NCT07274527	Medical College of Wisconsin	N/A
Not Yet Recruiting	Using Real-Time Lung Visuals to Reduce Mental Strain and Improve Diagnosis Speed NCT07511712	Second Affiliated Hospital, School of Medicine, Zhejiang University	N/A
Not Yet Recruiting	PEEP Strategies and Mechanical Power in Robotic Surgery NCT07536464	Ankara City Hospital Bilkent	N/A
Recruiting	Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients NCT07358039	Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer	N/A
Not Yet Recruiting	A Retrospective Clinical Study of Metabolic Status and Response to Nutritional Therapy in Patients With Mechan NCT07484126	Southeast University, China	—
Not Yet Recruiting	Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS NCT07521540	Hongying Jiang, MD	N/A
Recruiting	Effects of Periodic Recruitment Maneuvers on Atelectasis and Respiratory Mechanics During Elective Spine Surge NCT07325812	Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization	N/A
Not Yet Recruiting	Quantification of Systemic Congestion by Ultrasound As a Predictor of Weaning Failure From Mechanical Ventilat NCT07343882	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	N/A
Not Yet Recruiting	Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy NCT07212595	Stuart Goldstein, MD	Phase 2
Recruiting	Turkish Validity and Reliability of the Behavioral Indicators of Pain Scale(ESCID) NCT07467551	Saglik Bilimleri Universitesi	N/A
Not Yet Recruiting	Relationship Between the Level of Positive End-expiratory Pressure and Venous Congestion During Acute Respirat NCT07452952	University Hospital, Angers	—
Not Yet Recruiting	Regional Ventilation Evaluation During Neuro-injury Weaning Study NCT07067671	Assistance Publique - Hôpitaux de Paris	—
Recruiting	Flow-Controlled Versus Volume-Controlled Ventilation in Bariatric Surgery NCT07430111	Ankara Etlik City Hospital	N/A
Not Yet Recruiting	TRacheal Cuff PRessure Evaluation Study NCT06848010	Policlinico Hospital	N/A
Active Not Recruiting	Metabolic Response to Supine Physiotherapy in Mechanically Ventilated ICU Patients NCT07361419	Universidad de Extremadura	—
Recruiting	Optimizing Pain Treatment in Children On Mechanical Ventilation NCT06994442	Weill Medical College of Cornell University	Phase 3
Recruiting	Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Childr NCT07193719	Charite University, Berlin, Germany	Phase 1 / Phase 2
Not Yet Recruiting	The Ratio of Diaphragmatic Movement Between the Midaxillary Line and the Midclavicular Line Predicts the Succe NCT07235956	Zheng Qingjiang	—
Recruiting	Incidence and Determinants of Joint Contractures in Mechanically Ventilated ICU Patients NCT07339397	Elazıg Fethi Sekin Sehir Hastanesi	—
Recruiting	The Physiological Effect of RCexp on Ventilation/Perfusion Distribution NCT06919484	Southeast University, China	—
Recruiting	Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation NCT07224620	Beth Israel Deaconess Medical Center	Phase 2
Recruiting	Assessment of Respiratory Drive and Inspiratory Effort Across Pressure Support Levels in Patients After Major NCT07199881	Mahidol University	N/A
Not Yet Recruiting	Ketamine Sedation in the ICU (KANINE) RCT NCT06767358	McMaster University	Phase 3
Not Yet Recruiting	Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive NCT07093125	Universita degli Studi di Genova	—
Completed	Clinical Application of the Effect of Respiratory Muscles Electrical Stimulation on Weaning in Patients With D NCT07199036	Capital Medical University	N/A
Recruiting	Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients NCT07114289	Taipei Medical University Hospital	N/A
Recruiting	Shorter Weaning From Invasive Ventilation With Levosimendan NCT07105202	Radboud University Medical Center	Phase 4
Completed	Effect of Transition From Mechanical Ventilation to Spontaneous Breathing on Intraocular Pressure in ICU (VENT NCT07188922	Sevim Şenol Karataş	—
Completed	Comparison of Ventilatory Effects of Ultrasound-Guided Versus Bronchoscopy-Guided Percutaneous Dilatational Tr NCT07376525	Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization	—
Recruiting	Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE) NCT07188350	Hospital Moinhos de Vento	N/A
Not Yet Recruiting	Phrenic Nerve Stimulation for Reducing Ventilation Duration in Acute Cerebral Infarction: A Multicenter Random NCT07133932	Xuanwu Hospital, Beijing	N/A
Not Yet Recruiting	Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units NCT07129733	Hospital do Coracao	N/A
Recruiting	Effects of PERMISSive Lung-protective Ventilation on Outcome in Critically Ill Invasively Ventilated Patients NCT07077174	Reinier de Graaf Groep	N/A
Recruiting	Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Com NCT07099963	Laval University	—
Not Yet Recruiting	Comparison of Diaphragm Ultrasound and RSBI for Predicting Weaning Success in Mechanically Ventilated ICU Pati NCT07120438	Gadjah Mada University	—
Recruiting	Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Ris NCT07339449	University Hospital Dubrava	N/A
Recruiting	Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing El NCT07092943	Rawalpindi Medical College	N/A
Not Yet Recruiting	Effect of Ventilation Mode in the Pupillary Light Reflex: A Crossover Study NCT07082569	Evangelismos Hospital	N/A
Completed	Temporal Change in Parasternal Thickening Fraction as a Predictor for Weaning NCT07083128	Cairo University	—
Recruiting	Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient i NCT07109570	Leiden University Medical Center	—
Completed	Hyperoxia vs Normoxia During Cardiopulmonary Bypass NCT07510672	University of Padova	N/A
Recruiting	Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructiv NCT07022704	Cairo University	—
Recruiting	Effects of AbClo Fascial Approximation Device in Patients With Open Abdomen on Respiratory Mechanics NCT07154589	Unity Health Toronto	—
Recruiting	Combining Chest X-Ray and Arterial Blood Gas Findings to Predict Need for Mechanical Ventilation in Critically NCT07001696	Zagazig University	—
Recruiting	Intelligent Lung Support in the Intensive Care Unit NCT06595602	Technische Universität Dresden	—
Completed	Use of Endotracheal Tube Cuff Pressure to Assess Inspiratory Effort During Pressure Support Ventilation NCT06968793	Jian-Xin Zhou	N/A
Completed	Comparison of Automatic and Manual Endotracheal Tube Cuff Pressure Monitoring in Pediatric Intensive Care Pati NCT06965400	Dr. Behcet Uz Children's Hospital	N/A
Not Yet Recruiting	The Impact Of Respiratory Neuromuscular Stimulation On Patients With Invasive Mechanical Ventilation NCT06952335	Capital Medical University	N/A
Enrolling By Invitation	Safety and Efficacy of Low-Flow ECMO in a Multi-modal Cohort of Adults in Respiratory Failure NCT06938217	Institute for Extracorporeal Life Support	N/A
Not Yet Recruiting	Trial of Spontaneous Breathing Test NCT06593288	University of Sao Paulo	N/A
Recruiting	Effectiveness of Ventilation Modes in Intensive Care: A Comparison of Mandatory Minute Ventilation and Synchro NCT06961227	Harran University	—
Recruiting	Comparison of Physiological Effects of Two High-Flow Tracheal Oxygen Versus T-Piece During Spontaneous Breathi NCT06816706	Jian-Xin Zhou	N/A
Not Yet Recruiting	Evaluating the Clinical Effectiveness of "Endotracheal Tube Position Anomaly Alerting System" NCT06857019	Kaohsiung Medical University Chung-Ho Memorial Hospital	N/A
Recruiting	Prospective Multicentre Mixed Methods Study to Explore Extubation Practices and Respiratory Outcomes in Extrem NCT06808997	Centre Hospitalier Intercommunal Creteil	—
Recruiting	Remimazolam Besylate in Sedation of Postcardioperative Patients NCT06716840	First Affiliated Hospital of Zhejiang University	N/A
Completed	Comparison of Standard Versus Dynamic Compliance-Guided Individualized PEEP in Obese Patients Undergoing Spina NCT07388719	Konya City Hospital	N/A
Recruiting	Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome NCT06612242	Meir Medical Center	—
Not Yet Recruiting	The Impact of Lumboscopy Versus Laparoscopy on Ventilatory Mechanics NCT06776068	University of Chile	—
Recruiting	The Effects of Endotracheal Suctioning on Pain and Serum Markers NCT06692400	Loma Linda University	N/A
Completed	Correlation of EtCO₂- and P(A-a)O₂-Based Dead Space Calculations in Mechanically Ventilated ICU Patients NCT06947486	Karadeniz Technical University	—
Recruiting	Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation NCT06791915	Kocaeli City Hospital	—
Recruiting	Impact of PEEP on Respiratory Effort During Assisted Ventilation NCT07437846	Pontificia Universidad Catolica de Chile	N/A
Recruiting	Calibration of Esophageal Balloon Catheter in Spontaneous and Mandatory Mechanical Ventilation NCT06584604	Leiden University Medical Center	—
Recruiting	Impact of an Early and Extended Rehabilitation Program Combining Individually Tailored Nutrition and Physical NCT06581939	Nantes University Hospital	N/A
Recruiting	Ventilatory Settings and Monitoring Variables Associated With Weaning Failure in Critically Ill Patients NCT06683781	Hospital Italiano de Buenos Aires	—
Active Not Recruiting	DIAPHRAGM STRENGTH AND LUNG VOLUMES NCT07206459	Unity Health Toronto	—
Completed	Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients NCT06944431	Shin Kong Wu Ho-Su Memorial Hospital	N/A
Completed	Double Triggering Asynchrony in Mechanically Ventilated Patients. NCT07380607	Mansoura University	—
Recruiting	Personalized Ultrasound-Guided External Diaphragm Pacing to Improve Outcomes in Invasive Mechanically Ventilat NCT06609577	Daishan Jiang	N/A
Not Yet Recruiting	To Assess the Effectiveness of Three Distinct Mechanical Assisted Sputum Evacuation Apparatuses in the Treatme NCT06631716	Sir Run Run Shaw Hospital	—
Recruiting	Effect of Hypophosphatemia on Neuro-excursion Efficiency During Mechanical Ventilator Weaning NCT06754670	Peking Union Medical College	—
Recruiting	Influence of Sarcopenia on the Course of the Diseases NCT06829290	Universitatsmedizin Mainz - 1. Medizinische Klinik	—
Recruiting	Early Switch from Controlled to Assisted Ventilation NCT06438198	Erasmus Medical Center	N/A
Completed	Investigation of the Optimum PEEP Mechanical Power Relationship NCT06625099	Kocaeli City Hospital	—
Recruiting	The Impact of PEEP-guided Electrical Impedance Tomography on Oxygenation and Pulmonary Mechanics in Moderate-t NCT06733168	Vietnam Military Medical University	N/A
Recruiting	Sedation in ICU Patients With Mechanical Ventilation NCT06538883	Zhongda Hospital	N/A
Recruiting	Predictive Algorithms for Critical Rehabilitation Outcomes NCT06532994	Wuhan University	—
Completed	Sigh in Pressure Support Ventilation to Detect Respiratory System Compliance and Lung Recruitability NCT07172061	AUSL Romagna Rimini	N/A
Recruiting	Cytomegalovirus Reactivation in ICU Patients Requiring Prolong Mechanical Ventilation NCT06520605	Sanjay Gandhi Postgraduate Institute of Medical Sciences	—
Recruiting	Dead Space in Mechanical Ventilation With Constant Expiratory Flow NCT06024993	University Hospital, Antwerp	N/A
Recruiting	Study of Ventilator Associated Event During Intensive Care After Resuscitated Cardiac Arrest. NCT06466980	Centre Hospitalier Sud Francilien	—
Recruiting	Prognostic Estimates Among ICU Clinicians NCT06452797	Rush University Medical Center	N/A
Recruiting	Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability NCT06430554	Zhongda Hospital	—
Active Not Recruiting	Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Re NCT06737432	The University of Texas Medical Branch, Galveston	N/A
Not Yet Recruiting	Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients NCT06444997	Shanghai Zhongshan Hospital	Phase 4
Recruiting	Comparison of Lma-Protector With Endotracheal Tube: Evaluation of Respiratory Mechanical Parameters During Con NCT06474559	University Hospital of Patras	N/A
Recruiting	Regional Distribution of Ventilation at Different Respiratory Rates NCT06171477	Region Örebro County	N/A
Recruiting	The Effects of Positive End-expiratory Pressure (PEEP) on Optic Nerve Sheath Diameter in Laparoscopic Cholecys NCT06979999	Nigde Omer Halisdemir University	N/A
Recruiting	Use of a Physiotherapy Assessment to Predict Extubation Failure in Mechanically Ventilated Patients: the EPIC NCT06450678	Assistance Publique - Hôpitaux de Paris	—
Enrolling By Invitation	Optimal Positive End-Expiratory Pressure in Robotic-Assisted Thoracic Surgery Without Capnothorax NCT06784037	Hospital Clinic of Barcelona	—
Unknown	Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Childr NCT06157593	Chulalongkorn University	N/A
Completed	Pacing In Organ Donors (the POD Trial) NCT07505589	Fraser Health	N/A
Unknown	Power Dissipation in Flow-controlled Ventilation NCT06222463	Medical University Innsbruck	N/A
Enrolling By Invitation	A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU) NCT06042621	University of Wisconsin, Madison	—
Recruiting	HYPER MIND - Hyperoxia Effects on Cerebral Hemodynamics NCT07377162	Erasme University Hospital	N/A
Recruiting	Oxygen Consumption (VO2), Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Uni NCT06391424	Leiden University Medical Center	—
Completed	Personalized Decision-Aid to Guide Tracheostomy and Prolonged Mechanical Ventilation Decision-Making NCT07223918	Denver Health and Hospital Authority	—
Suspended	Post-hoc Analysis of Regional Pulmonary Perfusion and Hemodynamic Parameters Measured by Electrical Impedance NCT04249414	Drägerwerk AG & Co. KGaA	—
Active Not Recruiting	Ventilation dIstribution and effeCt of posTural Lateralization On Traumatic Lung injuRY: a Physiological Study NCT06196125	Unity Health Toronto	—
Recruiting	Reverse Trigger Phenotypification and Response to Ventilatory Adjustments NCT06148467	Hospital Civil de Guadalajara	—
Completed	Comparison of the Effects of Inspiratory Muscle Training Methods in Mechanically Ventilated Patients NCT06046690	Saglik Bilimleri Universitesi	N/A
Completed	AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport NCT06006208	Thomas Jefferson University	N/A
Completed	Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients NCT05718024	Peking University First Hospital	Phase 4
Completed	Evaluation of the Role of Acetyl Cysteine in Ventilator Associated Pneumonia by Carbapenem Resistance Klebsiel NCT07097727	Tanta University	Phase 1
Completed	Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress M NCT06098209	Tanta University	N/A
Completed	Solid State vs. Balloon Esophageal Catheter for Estimation of Pleural Pressure NCT05817968	Erasmus Medical Center	N/A
Completed	Mechanical Power-Guided Lung Protective Ventilation (VentCoach) in Acute Hypoxemic and/or Hypercapnic Respirat NCT07294768	Mayo Clinic	N/A
Recruiting	Physiological Studies in the Prone Position in Patients With ARDS NCT06586736	West China Hospital	—
Unknown	Effect of Early Extracorporeal Diaphragm Pacing Combined With Tilt Table in Ventilated Patients. NCT05953649	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	N/A
Recruiting	PMI Guide PS Setting in Pressure Support-ventilated Patients NCT05963737	Capital Medical University	N/A
Completed	Effects of Oxygen Supply After Lung Isolation in Thoracic Surgery NCT05946707	Medical University Innsbruck	N/A
Completed	Pressure Rise Time Modulation During Volume-Guaranteed Neonatal Ventilation NCT07465237	Hacettepe University	N/A
Completed	Effect of APRV vs. LTV on Right Heart Function in ARDS Patients: a Single-center Randomized Controlled Study NCT05922631	XiaoJing Zou,MD	N/A
Recruiting	The ED-AWARENESS-2 Trial NCT05534243	Washington University School of Medicine	N/A
Unknown	Diaphragmatic Speckle Tracking During Spontaneous Breathing Trial NCT06009731	Centre Hospitalier Universitaire, Amiens	—
Completed	Tracheal Ultrasound for Confirmation of ETT Placement in NICU NCT07073105	Ain Shams University	N/A
Unknown	Long-term Sedation With Remimazolam Besylate in Critically Ill Patients NCT05555667	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Phase 3
Unknown	The Effect of Ciprofol on Breathing Patterns, Respiratory Drive, and Inspiratory Effort in Mechanically Ventil NCT06287138	Capital Medical University	N/A
Completed	Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes NCT05906888	Henrik Endeman	—
Completed	Pulmonary Ventilation After Fiberoptic Bronchoscopy Using EIT NCT05875662	Peking University People's Hospital	—
Unknown	P0.1 and Extubation Failure in Critically Ill Patients NCT05802745	Cleveland Clinic Abu Dhabi	—
Completed	Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Venti NCT06994273	Tanta University	N/A
Recruiting	Analgesia-First Sedation in Trauma Patients NCT05751863	MemorialCare Health System	N/A
Recruiting	The Clinical Feasibility and Validity of PMIvent to Access Inspiratory Effort During Pressure Support Ventilat NCT05950893	Jian-Xin Zhou	N/A
Recruiting	Effect of a Personalized Weaning Strategy on Weaning Success NCT05719194	University Hospital, Clermont-Ferrand	N/A
Completed	Step 2 of A Two-step Trial to Evaluate the Effectiveness and Safety of Remimazolam Besylate for Sedation in IC NCT05782894	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Phase 3
Completed	Inspiratory Contribution of Pressure Support-ventilated Patients in Different PMI Conditions NCT05970393	Jian-Xin Zhou	N/A
Unknown	The Effect of Intraoperative Ventilation Mode on Hemodynamics and Lung Dynamics NCT05776589	Izmir Ataturk Training and Research Hospital	—
Completed	Influence of Inspiratory Pause on Ventilatory Efficiency in Robotic Surgery. A Prospective Paired Study. NCT05514366	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla	N/A
Unknown	Effect of Transpulmonary Pressure Guided Ventilation on Intraoperative Right Heart Function NCT05709041	University of Vermont Medical Center	N/A
Unknown	Effect of Early Non-invasive Phrenic Nerve Stimulation on Weaning in Mechanically Ventilated Patients NCT05629819	Bing Sun	N/A
Completed	Continuous Enteral Feeding Until Tracheostomy and Aspiration Risk NCT07508293	Bursa Yuksek Ihtisas Training and Research Hospital	—
Unknown	Inhalational Sedation and Mechanical Power NCT05559970	Mahidol University	N/A
Completed	Comparison of Volume-controlled and Pressure-controlled Ventilation in Clasp-knife Position NCT06056401	Sun Yat-sen University	N/A
Completed	Ketamine Versus Propofol as ICU Sedation NCT06243822	Menoufia University	Phase 4
Unknown	Global BurdEn of MechanIcal VeNtilatIon (GEMINI). VeNtilatIon (GEMINI Study) 2022 for VENTILAGROUP. NCT05392010	Hospital Universitario Getafe	—
Unknown	Tracheal Suctioning and Expiratory Pause in Bronchial Hygiene NCT05579145	Hospital de Clinicas de Porto Alegre	N/A
Recruiting	Improvement of Lung and Thoracic Compliance in ARDS Patients in Prone Position by Using Inflatable Air Bag NCT05515484	Centre Hospitalier Universitaire, Amiens	Phase 2
Recruiting	Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patien NCT05466708	The First Affiliated Hospital with Nanjing Medical University	Phase 4
Recruiting	Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome NCT05492344	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Completed	Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery NCT04381949	University Hospital, Rouen	N/A
Active Not Recruiting	The Value of Repeated BIOMarker Measurements During an SBT to Predict EXtubation Failure in ICU Patients NCT05637099	Henrik Endeman	—
Completed	Comparison of Weaning Parameters and Diaphragm Thickness Changes NCT06967623	Tarık Durna	—
Unknown	Anemia and Duration of Mechanical Ventilation NCT05382065	Mahidol University	—
Completed	Ventilation and Esophageal Pressure Changes NCT05859672	University of California, Davis	—
Completed	Optimization of Serum Phosphorus Level and Weaning From Mechanical Ventilation NCT05682846	Alexandria University	N/A
Completed	Tidal Volume Challenge to Assess Volume Responsiveness NCT05254951	Attikon Hospital	N/A
Completed	Thoracic Fluid Content by Electrical Cardiometry Versus Lung Ultrasound in Mechanically Ventilated Patients NCT05272982	Tanta University	—
Completed	Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surge NCT05365113	University Hospital, Clermont-Ferrand	N/A
Unknown	Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers - ICU Patients NCT05365854	University Hospital, Clermont-Ferrand	N/A
Withdrawn	ART-3 Pilot - Driving Pressure Limited Ventilation for Patients Without ARDS (ART3pilot) NCT02376647	Hospital do Coracao	N/A
Completed	A Biobank for Diaphragm Muscular Fiber NCT02900300	University Hospital, Montpellier	—
Unknown	Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU NCT05480787	The First Affiliated Hospital with Nanjing Medical University	Phase 4
Completed	Retrospective Study on Prolonged Sedation Effects With Inhaled Agents in PICU NCT05064592	Assistance Publique - Hôpitaux de Paris	—
Unknown	Machine Learning Ventilator Decision System VS. Standard Controlled Ventilation NCT05132751	Hu Anmin	N/A
Recruiting	Lung Ultrasound-Guided Fluid Deresuscitation in ICU Patients NCT05188092	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Recruiting	Prediction of Extubation Failure: A Multicenter Prospective Observational Study NCT05069441	Chongqing Medical University	—
Completed	Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Pati NCT05071352	Cairo University	Phase 3
Completed	Construction and Evaluation of Airway Leakage Risk Model of Patients With Endotracheal Tube NCT05921656	Affiliated Hospital of Nantong University	—
Terminated	NAVA vs. CMV Crossover in Severe BPD NCT04821453	Children's Hospital of Philadelphia	N/A
Unknown	Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome NCT05056090	University Hospital, Grenoble	N/A
Unknown	Use of Pressure Muscle Index to Avoid Over-assistance During Pressure Support Ventilation NCT05026463	Capital Medical University	N/A
Terminated	Feasibility of Music Therapy for Spontaneous Breathing Trials NCT05008328	Medical University of South Carolina	N/A
Completed	Multicenter Observational Study on Practice of Ventilation in Brain Injured Patients NCT04459884	University of Milano Bicocca	—
Completed	The Effect of Closed-Loop Versus Conventional Ventilation on Mechanical Power NCT04827927	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	N/A
Completed	Role of Pulmonary Perfusion on Tolerance to Supine Position in Patients With ARDS NCT05408442	Pontificia Universidad Catolica de Chile	—
Completed	Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation NCT04935814	University Hospital, Clermont-Ferrand	Phase 4
Completed	Continuous Flow Ventilation With the Ventijet System in Acute Respiratory Distress Syndrome: a First-in-Human NCT07121257	Hospital del Mar	N/A
Completed	Impact of a Communication Strategy in the Prevention of Depressive Symptoms in Patients with Covid-19 NCT05035563	Pontificia Universidad Catolica de Chile	N/A
Terminated	Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients NCT04876937	Peking University First Hospital	N/A
Completed	Effect of Mechanical Ventilation on Lung Development of Alveolar Stage NCT05498922	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	—
Completed	Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical NCT05038111	Far Eastern Memorial Hospital	—
Unknown	Evaluation of the Hemodynamic Effects of Transvenous Phrenic Stimulation NCT04680351	University Hospital, Angers	N/A
Unknown	RespirAq Humidifier Usability During Invasive Ventilation NCT04765878	Auckland University of Technology	N/A
Unknown	Cardiopulmonary Effect of Mechanical Ventilation in Children With Right Ventricular Hypertrophy NCT04825054	Limin Zhu	N/A
Completed	Intraoperative Protective Mechanical Ventilation in Patients Requiring Emergency Abdominal Surgery NCT03987789	University Hospital, Clermont-Ferrand	N/A
Completed	Validation of the Relationship Between Oxygenation Parameters and ORI™, in Mechanically Ventilated ICU Patient NCT05085119	University Hospital, Clermont-Ferrand	N/A
Completed	Nadroparin Pharmacokinetics in Different Stages of COVID-19 NCT05621915	Medical University of Lublin	—
Completed	Restrictive Use of Restraints and Delirium Duration in ICU NCT04273360	Assistance Publique - Hôpitaux de Paris	N/A
Completed	Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ve NCT04467086	Ottawa Hospital Research Institute	Phase 3
Active Not Recruiting	Titration of Oxygen Levels During Mechanical Ventilation With Electronic Alerts NCT04481581	Ohio State University	N/A
Completed	Comparison Volume-controlled Ventilation, Pressure-controlled Volume-guaranteed Ventilation, and Pressure-cont NCT06861959	Dr. Lutfi Kirdar Kartal Training and Research Hospital	N/A
Unknown	Epidemiological Characteristics and Outcomes of Patients Admitted to Kenyan Critical Care Units (EPOK). NCT05456217	Nat Intensive Care Surveillance - MORU	—
Completed	Improving Adherence to the Sedation-analgesia Protocol in Pediatric Intensive Care NCT07038850	Hospices Civils de Lyon	N/A
Completed	Influence of Renal Replacement TherApy on Indirect Calorimetry NCT04599569	University of Leipzig	—
Unknown	Respiratory Muscle Training in ICU Patients NCT04507451	University of Liege	N/A
Recruiting	Partial Neuromuscular Blockade in Acute Hypoxemic Respiratory Failure NCT04524585	University Health Network, Toronto	N/A
Completed	The Emergency Department Sedation Pilot Trial NCT04410783	Washington University School of Medicine	N/A
Unknown	Lung Microbiota and VAP Development (PULMIVAP) NCT04849039	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	—
Unknown	Sedation and Ventilator Weaning Protocol in PICU NCT04788589	Indonesia University	N/A
Withdrawn	The Brain and Lung Interaction (BALI) Study NCT04288076	Beth Israel Deaconess Medical Center	N/A
Withdrawn	Early Extubation for Patients With Acute Hypoxemic Respiratory Failure NCT04349332	University of Chicago	N/A
Unknown	The Effect of Positive End-Expiratory Pressure on Functional Residual Capacity During Mechanical Ventilation NCT03511651	Capital Medical University	N/A
Completed	Effects of Thoracic Epidural Analgesia in Geriatric Patients Undergoing Open Heart Surgery NCT04708080	Karadeniz Technical University	—
Completed	Effects of Music Therapy on Reducing Delirium in Mechanically Ventilated Adults in Intensive Care Unit NCT04065256	Taipei Medical University	N/A
Unknown	Identification of Risk Factors for Alteration of the Cellular-arterial Gradient of CO2 NCT04489615	University Hospital, Angers	—
Completed	The Effect of Preoperative Values on Mortality in Patients Undergoing Open Heart Surgery NCT04741555	Karadeniz Technical University	—
Unknown	Nesiritide for Ventilated Congestive Heart Failure NCT04455477	Shanghai Zhongshan Hospital	—
Unknown	Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19) NCT04497454	University of Sao Paulo General Hospital	N/A
Completed	WeanINg From Mechanical Ventilation for ARDS CovId-19 Patients Guided by Combined Thoracic UltraSound. NCT04372680	University Hospital, Toulouse	N/A
Completed	COVID-19 Mortality Prediction Model NCT04358510	Dascena	—
Completed	Dornase Alfa Administered to Patients With COVID-19 (DACOVID) NCT04387786	Feinstein Institute for Medical Research	—
Completed	Respiratory Decompensation and Model for the Triage of COVID-19 Patients NCT04390516	Dascena	N/A
Completed	Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina NCT04611269	Argentinian Intensive Care Society	—
Completed	PRactice of VENTilation in COVID-19 Patients (PRoVENT-COVID) NCT04346342	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	—
Completed	Ultrasound of Accessory Respiratory Muscles NCT04519450	Osijek University Hospital	—
Unknown	Mortality in Patients With Severe COVID-19 Pneumonia Who Underwent Tracheostomy NCT04642703	University of Chile	—
Completed	How NAVA Works in Preterm Infants With Irregular Respiratory Efforts NCT04659083	Inha University Hospital	—
Enrolling By Invitation	The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III)) NCT05298982	Australian and New Zealand Intensive Care Research Centre	—
Recruiting	Brain-injured Patients Extubation Readiness Study NCT04080440	University Hospital, Clermont-Ferrand	N/A
Completed	Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation NCT04319939	University of Chicago	—
Completed	Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome NCT04411459	Azienda Usl di Bologna	—
Unknown	Effect of Two Modes of Mechanical Ventilation on Metabolic Demands and Respiratory Mechanics NCT04205422	Assiut University	N/A
Unknown	Compare the Effects of Remifentanil and Fentanyl on the Duration of Mechanical Ventilation of ICU Patients NCT05014711	Capital Medical University	Phase 4
Unknown	Comparison of the Q-NRG+ Indirect Calorimetry Device Versus the V(Max) Encore Device in Mechanically Ventilate NCT04482556	Boston Children's Hospital	N/A
Completed	Positive End-expiratory Pressure Effects to Predict Fluid Responsiveness NCT04023786	Assistance Publique - Hôpitaux de Paris	N/A
Completed	Transcutaneous Diaphragm Electrical Stimulation in Critically Ill Patients NCT04171024	Groupe Hospitalier du Havre	Phase 4
Unknown	Calorimetry Guided Nutrition vs. Recommended Daily Intake in Weaning Chronically Ventilated Patients: Double B NCT04825717	Reuth Rehabilitation Hospital	N/A
Withdrawn	Spectral Edge Frequency From Spectral EEG Analysis to Guide Deep Sedation in the Critical Care Setting (Pilot) NCT04026451	University of Chile	N/A
Unknown	Evaluation of the Effect of a Speech Detection Tool on the Improvement of Phonation in Neuromuscular Patients NCT03504514	Centre d'Investigation Clinique et Technologique 805	N/A
Completed	Neuromuscular Blockade in the Intentive Care Unit, an Observational Study. NCT04028362	French Society for Intensive Care	—
Completed	Clinical Characteristics and Outcomes of Patients Requiring Mechanical Ventilation in an ICU- a Registry Based NCT06890936	Tribhuvan University Teaching Hospital, Institute Of Medicine.	—
Unknown	Continuous Evaluation of Diaphragm Function NCT03941002	University of Milan	N/A
Recruiting	RCT: Early Feeding After PEG Placement NCT04110613	Carilion Clinic	N/A
Completed	Ventilation With ASV Mode in Children NCT03930147	University of Lausanne Hospitals	N/A
Completed	Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients NCT04075006	King Faisal Specialist Hospital & Research Center	Phase 3
Unknown	Extrapulmonary Lung Protection Strategy for Patients With Mechanical Ventilation NCT03947476	Shanghai Zhongshan Hospital	—
Completed	Pediatric Acute Respiratory Distress Syndrome Asia Study NCT04068038	KK Women's and Children's Hospital	—
Unknown	Effect of High Flow Oxygen Therapy in Spontaneous Breathing Trial on Weaning in Mechanical Ventilated Patients NCT03929328	Sang-Min Lee	N/A
Terminated	Mitochondrial Dysfunction of Alveolar and Circulating Immune Cells During Acute Respiratory Distress Syndrome: NCT03955887	Centre Hospitalier Universitaire Dijon	—
Completed	Phrenic Nerve Block to Mitigate Self-inflicted Lung Injury NCT03978845	University of Sao Paulo General Hospital	N/A
Unknown	Prednisone Reduction in ICU Patients With COPD Exacerbation NCT03981081	Hôpital Universitaire Fattouma Bourguiba	Phase 4
Unknown	Transpulmonary Driving Pressure in ARDS COVID19 Patients NCT04381286	University Hospital, Montpellier	—
Unknown	Ultrasonography Guided Weaning Protocol Development to Predict Successful Weaning NCT03574233	Yonsei University	—
Completed	Confirmation of Ventilation and Intubation by Determination With Ultrasonography NCT04419064	University of Pittsburgh	—
Completed	Fluid Responsiveness Predicted by a Stepwise PEEP Elevation Recruitment Maneuver in Mechanically Ventilated Pa NCT04304521	Centre Hospitalier Universitaire de Saint Etienne	—
Completed	Driving Pressure in Trauma NCT03367442	University Hospital, Montpellier	—
Completed	High Flow Oxygen During Spontaneous Breathing Trial in Patients With High Weaning Risk Failure: Impact on the NCT03689309	Centre Hospitalier Régional d'Orléans	N/A
Active Not Recruiting	CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients NCT03471247	McMaster University	N/A
Completed	Echocardiographic Evaluation in ARDS Patients NCT03920189	University of Milan	—
Unknown	Evaluation of Decision Capacity of ICU Patients Under Sedatives. A Prospective Observational Multicenter Study NCT04193540	University Hospital, Clermont-Ferrand	—
Completed	Impact of Early Low-Calorie Low-Protein Versus Standard Feeding on Outcomes of Ventilated Adults With Shock NCT03573739	Nantes University Hospital	N/A
Unknown	Immersive Virtual Reality in Mechanically Ventilated Patients NCT03569358	Changi General Hospital	N/A
Completed	Electrical Impedance Tomography Guided Assessment of Optimum PEEP Levels During Mechanical Ventilation in Late NCT03704038	University Hospital Dubrava	N/A
Unknown	Inhomogeneous Ventilation in Adult Post-neurosurgical Patients NCT03830099	Capital Medical University	—
Completed	Diaphragmatic Ultrasound Associated With RSBI Predict Weaning Issue: the Rapid Shallow Diaphragmatic Index (RS NCT03479047	Centre Hospitalier Régional d'Orléans	N/A
Completed	Hyperoxemia and Ventilator-associated Pneumonia NCT03434821	University Hospital, Lille	—
Withdrawn	The Diversity of Intestinal Microbiota in Patients With Different Sedative-hypnotics Undergoing Mechanical Ven NCT03401736	Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University	N/A
Completed	Breath and Air Stacking on Respiratory Mechanics in Tracheostomized Patients NCT04012489	Brazilian Institute of Higher Education of Censa	N/A
Unknown	IVC Variation After VT Challenge to Predict Fluid Responsiveness NCT03397784	Shanghai Zhongshan Hospital	—
Active Not Recruiting	Early Non-invasive Ventilation and Progressive High Flow Oxygen Therapy Through Tracheostomy Tube Weaning Prot NCT06642714	Capital Medical University	N/A
Completed	Lung and Heart USG for Predicting Weaning in Neurosurgical Patients NCT03580993	National Institute of Mental Health and Neuro Sciences, India	—
Recruiting	Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury NCT07496125	Southeast University, China	—
Unknown	Hemodynamic Effects of PEEP in ARDS NCT03896802	University of Milan	N/A
Completed	Quality Control of Home Mechanical Ventilators NCT03854968	Hospital Clinic of Barcelona	N/A
Completed	the Effect of Different Mechanical Ventilation Modes on Optic Nerve Diameter and Conscious Functions NCT04413903	Bursa Yuksek Ihtisas Training and Research Hospital	N/A
Withdrawn	Glutamine Supplementation NCT02738762	Frisius Medisch Centrum	N/A
Completed	Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational Study NCT03351920	Poitiers University Hospital	—
Completed	Practice of Ventilation in Middle-Income Countries NCT03188770	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	—
Unknown	Mechanical Ventilation in Multiple Fracture Ribs NCT03314701	Assiut University	N/A
Completed	Ultrasound of Diaphragmatic Musculature in Mechanically Ventilated Patients. NCT03281785	Mansoura University	N/A
Unknown	REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Card NCT05029167	University of Southern Denmark	N/A
Completed	Inspiratory Muscle Training in Mechanically Ventilated Patients in Intensive Care Unit NCT06609564	Afyonkarahisar Health Sciences University	N/A
Completed	Assessment of Ventilatory Management During General Anesthesia for Robotic Surgery NCT02989415	Hospital Israelita Albert Einstein	—
Completed	Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use NCT04263662	Boston Children's Hospital	—
Completed	TEDS in Prolonged Mechanical Ventilation NCT04741724	Chang Gung University	N/A
Completed	Patient-ventilator Asynchrony in Patients With Brain Injury NCT03212482	Jian-Xin Zhou	—
Completed	Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time NCT03076983	Drägerwerk AG & Co. KGaA	—
Completed	The Effect of Semi-recumbent Position With Exercise Training on Long-term Ventilator-dependent Patients NCT04822831	Taoyuan General Hospital	N/A
Completed	Comparison of the LMA Protector and the I-gel NCT03078517	SMG-SNU Boramae Medical Center	N/A
Completed	Predictors Of Successful Extubation in Critically Ill Patients: Multicentre Observational Study NCT03185962	Osaka University	—
Completed	Decreasing Trigger Sensitivity Could Assist PEEP to Further Improve Regional Ventilation Distribution NCT03241654	Capital Medical University	—
Completed	Transcutaneous Electrical Diaphragmatic Stimulation in PMV Patients NCT04281810	Chang Gung Memorial Hospital	N/A
Active Not Recruiting	Measuring Outcomes of Activity in Intensive Care NCT03115840	Vanderbilt University Medical Center	—
Completed	Ventilator Hyperinflation With Increase of Inspiratory Time NCT03630510	Brazilian Institute of Higher Education of Censa	N/A
Terminated	Brain Computer Interface for Communication in Ventilated Patients NCT02791425	University of Michigan	N/A
Completed	Expiratory Muscle Function in Critically Ill Ventilated Patients NCT04333186	Amsterdam UMC, location VUmc	—
Unknown	Prospective Clinical Study of PCV and PCV-VG in Patients Undergoing Bariatric Surgery NCT03150264	Huashan Hospital	N/A
Completed	Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients NCT03030911	Cairo University	Phase 4
Unknown	Music in Vein in the Intensive Care Unit NCT04291677	Juan Carlos Montejo González	N/A
Completed	Influence of Respiratory Mechanics on Diaphragmatic Dysfunction in COPD Patients Who Have Failed NIV (RHYDIAN) NCT03852394	University of Modena and Reggio Emilia	—
Completed	Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatr NCT03155555	Post Graduate Institute of Medical Education and Research, Chandigarh	—
Completed	Visual Assessment for Pressure-time Curve NCT03096106	Capital Medical University	—
Unknown	Cardiac, Pulmonary and Diaphragm Sonography for the Early Diagnosis of the Different Etiologies Underlying Fai NCT03261440	Centre Hospitalier Universitaire Dijon	—
Unknown	Proof of Concept Trial to Confirm That the Recovery of Patients Treated in the Intensive Care Unit Requiring M NCT02828722	Achros Health Technologies Corporation	N/A
Completed	Weaning From Mechanical Ventilation Guide by Assessment of Lung Tidal Distribution With EIT NCT03118804	Southeast University, China	—
Completed	Semi-quantitative Cough Strength Score (SCSS) NCT03031860	Assiut University	—
Completed	Ultrasonography for Prediction of Extubation Success: a Holistic Approach NCT04196361	Amsterdam UMC, location VUmc	—
Completed	Effect of Positive End-expiratory Pressure on Optimal Balloon Volume During Esophageal Pressure Monitoring NCT02976844	Capital Medical University	—
Completed	Assessment of Esophageal Pressure Reliability to Estimate Pleural Pressure in Critically Ill Children NCT02762279	St. Justine's Hospital	N/A
Completed	Work of Breathing Assessment During Weaning From Mechanical Ventilation NCT02762292	St. Justine's Hospital	N/A
Completed	Comparison of Esophageal and Central Venous Pressure for Estimating Transpulmonary Pressure Changes NCT04443491	University of Siena	—
Completed	Does Preconditioning Affects Other Organs in Patients Undergoing Open Heart Surgery ? NCT03097692	Assiut University	N/A
Completed	PROne POsition and Volumetric CAPnography NCT02816190	Hopital of Melun	—
Completed	Shunt Evaluation With ALPE System in Thoracic Surgery NCT02968550	Università degli Studi di Ferrara	—
Unknown	Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine in Mechanically Ventilated Pa NCT02528513	West China Hospital	Phase 4

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