NCT07099963

Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Laval University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.

Detailed description

The aim of the study is to: 1. Evaluate whether the initial ventilation settings (tidal volume and respiratory rate) during one-lung ventilation are appropriate to prevent respiratory acidosis. 2. Compare the ventilation settings (tidal volume and respiratory rate) made by clinicians with those proposed by an smartphone application ''VentilO''.

Conditions

• Thoracic
• Surgery
• Mechanical Ventilation
• Hypercapnia
• Acidosis
• One Lung Ventillation (OLV)
• Smartphone Application

Interventions

Type	Name	Description
OTHER	one lung ventilation	Arterial blood gases during one lung ventilation

Timeline

• Start date: 2025-08-01
• Primary completion: 2025-12-01
• Completion: 2026-06-01
• First posted: 2025-08-01
• Last updated: 2025-08-06

Locations

1 site across 1 country: Canada