Trials / Completed
CompletedNCT03434821
Hyperoxemia and Ventilator-associated Pneumonia
Impact of Hyperoxemia on Incidence of Ventilator-associated Pneumonia
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 534 (actual)
- Sponsor
- University Hospital, Lille · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this prospective cohort single-center observational study is to determine the impact of hyperoxemia on ventilator-associated pneumonia (VAP) occurrence. * SpO2 will be continuously recorded in order to determine the percentage of time spent with hyperoxemia. * Patients with VAP will be prospectively identified. * Patient characteristics and risk factors for VAP will be prospectively collected. * Oxidant stress will be prospectively investigated in study patients: glutathion peroxidase (GPX), plasmatic superoxyde dismutase (SOD), total plasmatic antioxidant status (SAT) and urinary 8-isoprostanes will be performed at ICU admission, once a week, and at VAP occurrence. Patients with VAP will be compared with those with no VAP
Conditions
Timeline
- Start date
- 2018-03-15
- Primary completion
- 2022-04-30
- Completion
- 2022-04-30
- First posted
- 2018-02-15
- Last updated
- 2022-07-06
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03434821. Inclusion in this directory is not an endorsement.