NCT04741724

TEDS in Prolonged Mechanical Ventilation

Effect of Transcutaneous Electrical Diaphragmatic Stimulation in Prolonged Mechanical Ventilation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: Chang Gung University · Academic / Other
• Sex: All
• Age: 20 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Muscle atrophy and diaphragm dysfunction are common with prolonged mechanical ventilation (PMV). Electrical stimulation has been shown to be beneficial in severe chronic heart failure and chronic obstructive pulmonary disease. However, its effect on PMV is unclear. This study examined the effects of transcutaneous electrical diaphragmatic stimulation (TEDS) on respiratory muscle strength and weaning outcomes in patients with PMV.

Detailed description

Subjects on ventilation for ≥21 days were randomly assigned to TEDS or control groups. The TEDS group received muscle electrical stimulation for 30 min/session/day throughout the intervention. Weaning parameters and respiratory muscle strength (Pimax, Pemax) were assessed. The hospitalization outcome, including weaning rate and length of stay, was followed up until discharge.

Conditions

• Mechanical Ventilation

Interventions

Type	Name	Description
DEVICE	TEDS	An non-invasive intervention. During the intervention, the electrode was placed on the skin stimulated muscle.

Timeline

• Start date: 2017-07-01
• Primary completion: 2018-12-31
• Completion: 2019-03-01
• First posted: 2021-02-05
• Last updated: 2023-08-30

Locations

1 site across 1 country: Taiwan