NCT05026463

Use of Pressure Muscle Index to Avoid Over-assistance During Pressure Support Ventilation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Capital Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Pressure support ventilation (PSV) is the most commonly used mode in mechanical ventilated patients. Studies have shown that over-assistance was prevalent in patients undergoing PSV. Up to now, no reliable method has been recommended to select an "optimal" inspiratory support level. Pressure muscle index (PMI) was introduced recently to evaluate the degree of spontaneous breathing effort. We hypothesize that PMI might be used as an indicator for over-assistance during PSV. In this randomized crossover study, inspiratory support is set at three levels according to negative, positive and zero PMI. Inspiratory effort, work of breathing, and respiratory mechanics are compared among the three inspiratory pressure support levels.

Conditions

• Mechanical Ventilation

Interventions

Type	Name	Description
PROCEDURE	Inspiratory support level	Inspiratory support is the pressure delivered by the ventilator during pressure support ventilation.

Timeline

• Start date: 2021-09-01
• Primary completion: 2022-01-01
• Completion: 2022-02-01
• First posted: 2021-08-30
• Last updated: 2022-01-11

Locations

2 sites across 1 country: China