Clinical Trials Directory

Trials / Sponsors / Goethe University

Goethe University

Academic / Other · 97 registered clinical trials15 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingDynamic Networks in Depression Treatment: Mechanisms of Change in Pharmacological, Psychological and Combined
Depression - Major Depressive Disorder
Phase 42026-02-01
RecruitingUrolithin A in Patients With Previously Untreated Solid Tumors Receiving Immune Checkpoint Inhibitors
Solid Cancer, Non-Small Cell Lung Cancer, Melanoma
N/A2026-01-02
RecruitingDynamic Network Response to TMS Treatment
MDD
2025-11-24
RecruitingRobot-assisted Cystectomies With Regard to Blood Loss, Pain and Transfusions.
Transfusions, Cystectomy, Blood Loss Requiring Transfusion
2025-08-01
RecruitingEffects of Frontopolar TMS in Alcohol Craving
Alcohol Addiction
N/A2025-05-16
Not Yet RecruitingCohort of the Specialist Network Infectious Diseases
Infectious Diseases and Manifestations
2025-03-20
RecruitingEPIDURAL- Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia
Neuroaxial Analgesia Procedures
2025-03-01
RecruitingIsatuximab in Adult Patients With Cytologic or Molecular Relapsed/Refractory CD38 Positive T-cell Acute Lympho
T-ALL
Phase 22024-10-22
RecruitingExpected and Actual Preterm-Birth and Parental Distress: Impact on Children's Mental Health
Preterm Birth, Psychological Distress, Mental Health
2024-07-08
RecruitingProcess-based Therapy for Difficult-to-treat Anxiety Disorders and Depression
Depression, Anxiety Disorder
N/A2024-01-29
Active Not RecruitingFeasibility of Process-based Therapy in a Naturalistic Setting
Depressive Disorder, Anxiety Disorder
N/A2023-11-04
CompletedEvaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini
Bloodloss in Pregnancy
2023-10-01
RecruitingMAIN-IMAGE Registry
Coronary Artery Disease
2023-09-26
RecruitingRandomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and S
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Phase 22023-07-14
CompletedVolatiles in Critical Care After Free Flap Surgery
Sedation Set-up Time, Additional Time Required for Volatile Sedation
N/A2023-04-01
CompletedProspective Evaluation of Jugular Vein Thrombi After CPB Cervical Cannulation
Post-interventional VJI Thrombi After CPB
2022-12-01
UnknownEvaluation of a Smartphone Application for Self-help for Social Anxiety
Social Anxiety
N/A2022-10-01
CompletedMechanical Cardiopulmonary Resuscitation During Treatment of Acute Respiratory Failure Through Extracorporeal
Cardiovascular Resuscitation, Venovenous Extracorporeal Membrane Oxygenation
2022-06-01
CompletedTherapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.
Extracorporeal Membrane Oxygenation Complication, Outcome, Fatal
2022-05-01
Active Not RecruitingVenetoclax in Addition to Blinatumomab in Adult Patients With Relapsed/Refractory B Cell Precursor Acute Lymph
ALL, Recurrent, Adult
Phase 1 / Phase 22021-12-15
RecruitingAdditional Chemotherapy for EGFRm Patients with the Continued Presence of Plasma CtDNA EGFRm At Week 3 After S
NSCLC Stage IIIB, NSCLC Stage IV
Phase 22021-11-12
CompletedProspective Evaluation of Volatile Sedation After Heart Valve Surgery
Valve Heart Disease, Awakening Early
N/A2021-11-01
CompletedCapecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Canc
Rectal Cancer
Phase 12021-08-20
CompletedProspective Electroencephalography Evaluation of Sedation in COVID-19
Conscious Sedation, Pathologic Processes, Electroencephalogram
2021-04-01
UnknownIntersectoral Platform (SÜP) of the National Pandemic Cohort Network (NAPKON)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
2020-11-04
Active Not RecruitingCharacterization of Metabolic Changes in the Glioma Tumor Tissue Induced by Transient Fasting (ERGO3)
Glioma, Mixed
N/A2020-08-19
CompletedTiming of Tracheostomy in COVID-19 - Impact on Mortality
Tracheostomy
2020-04-01
CompletedEvaluation of Sedation in COVID-19 ARDS
Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2, Hypnotics and Sedatives
2020-03-01
Active Not RecruitingRadiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. a Multicenter, Randomized, Phase II Tria
Anal Cancer, Anal Carcinoma, Anal Cancer Stage III
Phase 22020-01-07
UnknownHepcidin as a Predictor for the IVI Mediated Increase in Haemoglobin Levels
Anemia, IV Iron
2019-04-12
UnknownDrug Monitoring in Critically Ill Patients During Extracorporeal Life Support
Drug Monitoring of Antiinfectives in Critically Ill Patients Receiving Extracorporeal Life Support
2019-01-01
CompletedEvaluation of qSOFA in Neurosurgical Patients
Brain Injuries, Brain Trauma, Subarachnoid Hemorrhage
2018-08-20
UnknownHigh-intensity Functional Circuit Training and Cognitive Function
Exercise, Cognition
N/A2018-08-01
TerminatedPanobinostat Maintenance After HSCT fo High-risk AML and MDS
Acute Myeloid Leukaemia (AML), Myelodysplastic Syndromes (MDS)
Phase 32018-07-24
CompletedTreatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab
B-Precursor ALL
Phase 22018-06-01
CompletedValidation of CMR Against Invasive Haemodynamics in Patients With HFpEF
Heart Failure With Normal Ejection Fraction
2018-01-14
CompletedAssessment of Hemostatic Profile in Liver Cirrhosis
Coagulation Disorder
2017-12-01
CompletedRandomized Phase-II Study of Nivolumab Plus Ipilimumab vs. Standard of Care in Untreated and Advanced Non-clea
Metastatic Renal Cell Carcinoma
Phase 22017-11-01
UnknownNeurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive F
Anterior Cruciate Ligament Reconstruction
2017-10-01
UnknownCharacteristics of Primary and Plasmatic Hemostasis in Preeclampsia
Coagulation Disorder, Blood, Platelet Function
2017-09-01
CompletedDetecting Sepsis in Patients With Severe Subarachnoideal Hemorrhage
Subarachnoid Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal, Sepsis Syndrome
2017-06-01
CompletedBlinatumomab in Adult Patients With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia
ALL, Recurrent, Adult
Phase 22017-03-15
CompletedPrevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder
Attention-Deficit / Hyperactivity Disorder, Depression, Obesity
Phase 22017-03-13
RecruitingGerman Pediatric Hemophilia Research Database
Hemophilia A, Hemophilia B, Children
2017-01-01
CompletedAcute Effects of Foam Rolling on Viscoelastic Tissue Properties and Fascial Sliding
Fascia, Self-Myofascial-Release, Passive Stiffness
N/A2016-09-01
CompletedOptimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic L
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Phase 32016-08-01
CompletedCell Therapy by Autologous BMC for Large Bone Defect Repair
Humerus Fracture Displaced Proximal
Phase 22016-07-02
CompletedFaster Back Home: Efficacy of a High-intensity Endurance Training
Healthy
N/A2016-07-01
CompletedImplication of Stiffness of the Hamstrings, Achilles Tendon and Calf Muscles for Jumping Performance
Tissue Compliance
N/A2016-07-01
CompletedCervical Kinematics' Reliability: Zero Positioning Using a 3-D-bulls Eye Spirit Level
Kinematics, Reliability, Cervical
N/A2016-03-01
UnknownDiagnostic Algorithm for Appendizitis (DIALAPP)
Reduction of Negative Appendectomy Rate
2015-11-01
CompletedRemote Effects of Lower Limb Stretching
Fascia, Randomized Controlled Trial, Stretching
N/A2015-08-01
CompletedGingival Bleeding and Von Willebrand Disease Typ 2 and 3
Gingival Bleeding, Von Willebrand Diseases
2015-07-16
UnknownLong-term Results After Systematic Periodontal Therapy
Tooth Loss
2015-06-01
CompletedImmediate Effects of Self-myofascial Release on Latent Trigger Point Sensitivity
Trigger Points
N/A2015-05-01
CompletedPhysical Function and Activities of Daily Living in Cancer Patients During Chemotherapy
Advanced Gastrointestinal Cancer
N/A2014-08-01
CompletedAcuTA: Acupuncture in Test Anxiety
Test Anxiety, Experimental Setting (Trier Social Stress Test TSST)
N/A2014-04-01
CompletedFeedback and Psychotherapeutic Competencies
Mental Disorders
N/A2013-11-01
CompletedASS-Nonresponse Following Cardiac Surgery as Assessed With Multiple Electrode Aggregometry
ASS-Nonresponse
2013-08-01
CompletedCell Therapy by Bone Marrow-derived Mononuclear Cells (BMC) for Large Bone Defect Repair: Phase-I Clinical Tri
Humerus Fracture Displaced Proximal
Phase 12013-07-01
UnknownPoint-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study
Coagulopathy During Cardiac Surgery
N/A2013-07-01
CompletedIgM-enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis
Sepsis
2013-01-01
CompletedMonitoring Platelet Function During Continuous Hemodialysis
Platelet Function
2012-12-01
CompletedPilot-Study DCPT for PTSD in Adolescents and Young Adults
PTSD
N/A2012-11-01
CompletedActivated MMP-8 as Diagnostic Test for Periodontitis
Generalized Chronic Periodontitis
2012-09-01
UnknownHemodynamic Changes in Altitude Adaptation
Acute Mountain Sickness, High Altitude Pulmonary Edema, High Altitude Cerebral Edema
2012-08-01
CompletedA Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia
Acute Lymphoblastic Leukemia, Leukemia, Myelocytic, Acute, Chronic Myelogenous Leukemia With Crisis of Blast Cells
Phase 12012-06-01
CompletedStudy With Temsirolimus Added to Standard Chemotherapy for Patients Over 60 Years With Acute Myeloblastic Leuk
Acute Myeloblastic Leukemia
Phase 22012-05-01
CompletedEvaluation of Efficacy and Safety of Nilotinib in Combination With Chemotherapy in Elderly Patients With Phila
Philadelphia Chromsome Positive Acute Lymphoblastic Leukemia
Phase 22012-01-01
CompletedAcceptance and Efficacy of Live Supervision
Mental Disorders
N/A2012-01-01
CompletedStudy of Frontline Dasatinib Plus Chemotherapy in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemi
Philadelphia Positive Acute Lymphoblastic Leukemia
Phase 22011-11-01
CompletedFollow-up of Children With Gastrointestinal Malformations and Postnatal Surgery
Digestive System Abnormalities
2011-09-01
CompletedInfluence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery
Acquired Platelet Function Disorder
2011-06-01
CompletedMonitoring of the Cerebral Tissue Oxygenation and Perfusion in the Adapting Climber During Sleep in High Altit
Environmental Sleep Disorder, Cheyne-Stokes Respiration, Altitude Sickness
2011-05-01
UnknownInternational Multicenter Registry for Mechanical Recanalization Procedures in Acute Stroke
Acute Stroke
2011-01-01
UnknownInfluence of Clonidine on Thrombozytes of Blood of Patients Under Anticoagulation Therapy With ASS and Clopido
Anticoagulation
2010-10-01
CompletedPrioritising and Optimising Multi-medication in Multimorbidity
Chronic Disease
N/A2010-08-01
CompletedEfficacy of Cognitive Restructuring and Imagery Modification to Reduce the Feeling of Being Contaminated After
Sexual Abuse, Posttraumatic Stress Disorder
N/A2010-06-01
CompletedComparing Cognitive Therapy and Exposure Therapy in Individuals With Hypochondriasis
Hypochondriasis, Somatoform Disorders
Phase 32010-06-01
UnknownEvaluation of Educational Intervention to Teach Principles of Evidence-based Medicine (EbM) in Biology Classes
Health Knowledge, Attitudes, Practice
N/A2010-02-01
UnknownSafety and Immune Response to Adjuvanted A(H1N1)v Influenza Vaccine in HIV-1 Infected and Immunosuppressed Adu
HIV-1 Infection, Cancer, Immunosuppression
Phase 42009-11-01
CompletedStudy on the Psychotherapeutic Treatment of Chronic Nightmares
Nightmare Disorder
N/A2009-10-01
CompletedConventional Versus Point-of-care Based Coagulation Management
Cardiac Surgery, Coagulation Management
Phase 42009-06-01
CompletedModified Ultrafiltration in Cardiac Surgery
Coagulopathy, Rethoracotomy, Blood Loss
2009-06-01
RecruitingGMALL Registry and Collection of Biomaterial: Prospective Data Collection Regarding Diagnosis, Treatment and O
Acute Lymphoblastic Leukemia, Leukemia, Non-Hodgkin's Lymphoma
2009-02-01
CompletedComparative Study of Intraoperative MRI-guided vs. Conventional Glioma Surgery
Glioma
N/A2007-10-01
CompletedCytokines in Papillon-Lefèvre Syndrome
Papillon-Lefevre Disease
2006-07-01
CompletedImatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)
AML
Phase 22004-07-01
CompletedTreatment of Acute Lymphoblastic Leukemia or Aggressive Lymphoma With Relapse in Central Nervous System With D
Adult Acute Lymphocytic Leukemia
Phase 2 / Phase 32004-04-01
CompletedTreatment of Relapsed T-cell Acute Lymphoblastic Leukemia or T-lymphoblastic Lymphoma With MabCampath
Adult Acute Lymphocytic Leukemia T-cell, Lymphoma, Lymphoblastic
Phase 22004-02-01
Completed506U78 In Relapsed Or Refractory Acute Lymphoblastic Leukemia (T-ALL)
T-ALL, T-NHL (Lymphoblastic)
Phase 22003-06-01
CompletedTreatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lympho
Adult Acute Lymphocytic Leukemia, High-grade Lymphoma
Phase 32003-05-01
CompletedGerman Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
Adult Acute Lymphocytic Leukemia
Phase 42003-04-01
CompletedGerman Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Adult Acute Lymphocytic Leukemia
Phase 42003-01-01
CompletedGerman Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)
Adult Acute Lymphocytic Leukemia
Phase 41999-10-01
CompletedTreatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia
Adult Acute Lymphocytic Leukemia
Phase 41997-02-01
CompletedGerman Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)
Adult Acute Lymphocytic Leukemia
Phase 41993-04-01