Trials / Completed
CompletedNCT00198978
German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Multicenter Study To Optimize Treatment in Elderly Patients (> 55 Years, No Upper Age Limit) With Acute Lymphoblastic Leukemia (GMALL Elderly 1/2003)(Amend 2)
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 377 (actual)
- Sponsor
- Goethe University · Academic / Other
- Sex
- All
- Age
- 55 Years
- Healthy volunteers
- Not accepted
Summary
The study evaluates the efficacy and tolerability of a dose-reduced chemotherapy for the treatment of elderly patients with acute lymphoblastic leukemia. In patients with expression of CD20 on leukemic cells the efficacy and tolerability of additional application of Rituximab together with chemotherapy is evaluated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cyclophosphamide | |
| DRUG | Dexamethasone / Prednisolone | |
| DRUG | Cytarabine | |
| DRUG | Idarubicin | |
| DRUG | Granulocyte-Colony-Stimulating Factor | |
| DRUG | Mercaptopurine | |
| DRUG | Methotrexate | |
| DRUG | Rituximab | |
| DRUG | HDARAC | |
| DRUG | Vincristine | |
| DRUG | Depocyte | |
| DRUG | Asparaginase |
Timeline
- Start date
- 2003-01-01
- Primary completion
- 2011-06-01
- Completion
- 2014-06-01
- First posted
- 2005-09-20
- Last updated
- 2023-03-20
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00198978. Inclusion in this directory is not an endorsement.