NCT04265508

Assessment of Hemostatic Profile in Liver Cirrhosis

Assessment of Hemostatic Profile in Patients With Mild to Advanced Liver Cirrhosis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 67 (actual)
• Sponsor: Goethe University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Our study included both in- and outpatients suffering from liver cirrhosis attending the out- and inpatient care of the department of hepatology. Demographic and biochemical data as well as medical history including cause of liver cirrhosis, end stage kidney failure and medication with anticoagulants were recorded. To assess the hemostatic profile, platelet function was analyzed by multiple electrode aggregometry (MEA) using Multiplate (ADP-, ASPI- and TRAP-test) and thrombelastometry using ROTEM (EXTEM, INTEM, FIBTEM).

Conditions

• Coagulation Disorder

Interventions

Type	Name	Description
OTHER	Assessment of hemostatic profile	To assess the hemostatic profile, platelet function was analyzed by multiple electrode aggregometry (MEA) using Multiplate (ADP-, ASPI- and TRAP-test) and thrombelastometry using ROTEM (EXTEM, INTEM, FIBTEM)

Timeline

• Start date: 2017-12-01
• Primary completion: 2018-05-01
• Completion: 2018-11-01
• First posted: 2020-02-11
• Last updated: 2020-02-12

Locations

1 site across 1 country: Germany