NCT01354847

Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery

Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery - a Prospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: Goethe University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is planned to investigate the relationship between duration of extracorporeal circulation and the extent of (acquired) platelet dysfunctions in patients undergoing cardiac surgery.

Detailed description

Patients undergoing complex cardiac surgery are planned to be included. At several intra- and postoperative measuring point, blood is drawn for multiple electrode aggregometry to investigate ex-vivo platelet aggregation as a surrogate for platelet function. Transfusion rate of allogenic blood products as well as postoperative blood loss is planned to be recorded.

Conditions

• Acquired Platelet Function Disorder

Interventions

Type	Name	Description
DEVICE	Multiple electrode aggregometry analyses (Multiple Electrode Aggregometry, Multiplate(R), Verum Diagnostica, Munich, Germany)	ex vivo platelet aggregation at several intraoperative and postoperative measuring points.

Timeline

• Start date: 2011-06-01
• Primary completion: 2013-10-01
• Completion: 2013-10-01
• First posted: 2011-05-17
• Last updated: 2013-10-28

Locations

1 site across 1 country: Germany