NCT01826123

Point-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study

Point-of-Care Testing - A Prospective, Randomized, Controlled Multicenter Study of Efficacy in Coagulopathic Cardiac Surgery Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: Goethe University · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Recently, the investigators study group showed in a mono center study that Point of Care (POC) based hemotherapy may reduce transfusion rates of allogenic blood products in perioperative care of coagulopathic cardiac surgery patients. The investigators aim to verify the obtained results by conducting this multicenter study.

Conditions

• Coagulopathy During Cardiac Surgery

Interventions

Type	Name	Description
DEVICE	Conventional laboratory testing (Central laboratory)	aPTT, INR, fibrinogen concentration, platelet count
DEVICE	POC testing	ROTEM: Clotting time (CT) in the EXTEM- and INTEM-test, Maximal clot firmness in the FIBTEM-test, Clot Lysis Index (CLI) multiplate: Area under the aggregation curve following stimulation with arachidonic acid (ASA) and Adenosine diphosphate (ADP)

Timeline

• Start date: 2013-07-01
• Primary completion: 2019-05-01
• Completion: 2019-05-01
• First posted: 2013-04-08
• Last updated: 2017-05-04

Locations

4 sites across 2 countries: Austria, Germany