NCT06517589

Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

Process-based Therapy vs. Routine-CBT for Difficult-to-treat Anxiety Disorders and Depression

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Goethe University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to test the relative efficacy of Process-based Therapy compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.

Detailed description

Process-based Therapy (PBT) is a new framework to intervention planning, based on the use of ecological momentary assessment (EMA) data, feedback of dynamic network analysis and matching of interventions to central nodes of the network. Although preliminary support for its applicability has been reported from a single-case study, there are no data on the feasibility and effectiveness in a larger clinical sample. The investigators have translated a Training Manual of PBT and modified for delivery of CBT in Mental Health Service. The aim of this study is to test the relative efficacy of PBT compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.

Conditions

• Depression
• Anxiety Disorder

Interventions

Type	Name	Description
OTHER	Process-based Cognitive Behavioral Therapy (PBT)	PBT (20 sessions), intervention planning based on the use of EMA data, feedback of dynamic network analysis and matching of interventions to central nodes of the network.
OTHER	Cognitive Behavioral Therapy (CBT)	CBT (20 sessions), intervention planning as usual based on manual.

Timeline

• Start date: 2024-01-29
• Primary completion: 2024-12-31
• Completion: 2025-07-30
• First posted: 2024-07-24
• Last updated: 2024-07-30

Locations

1 site across 1 country: Germany