| Suspended | Glucose and Blood Pressure During Pregnancy NCT04979312 | Mayo Clinic | N/A |
| Not Yet Recruiting | Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women NCT07458997 | Hong Kong Metropolitan University | N/A |
| Not Yet Recruiting | Pharmacokinetic Study to Evaluate Safety and Tolerability of EG-101 in Healthy Female Volunteers as a Safety L NCT07327255 | Evergreen Therapeutics, Inc. | Phase 1 |
| Recruiting | Placental Biology in Health and Disease NCT07470320 | University of Oxford | — |
| Recruiting | Fetal Fornix and Hippocampus in Pregnant Women With Early-Onset Preeclampsia NCT07245056 | Ankara Etlik City Hospital | N/A |
| Active Not Recruiting | Mortality Outcome of Controlled Hypertension NCT07187596 | DejthidaNathaphong | — |
| Recruiting | Virtual Reality-Based and Face-to-Face Relaxation Programs in Pregnant Women With Preeclampsia NCT06893510 | Istanbul University - Cerrahpasa | N/A |
| Recruiting | Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia. NCT06122220 | Saint Thomas Hospital, Panama | N/A |
| Recruiting | Vitamin D for Preventing Recurrent Preeclampsia in Pregnant Women NCT07288801 | Nishtar Medical University | Phase 4 |
| Not Yet Recruiting | Oxford Luteal Dysfunction and Placental Insufficiency Study NCT07072052 | University of Oxford | — |
| Not Yet Recruiting | Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guid NCT06107335 | The University of Texas Health Science Center, Houston | Phase 4 |
| Recruiting | Autophagy/Apoptosis Balance in Placental Vascular Pathologies NCT06779916 | Centre Hospitalier Universitaire de Nīmes | — |
| Withdrawn | DM199 for Pregnancy Complications NCT06875141 | DiaMedica Therapeutics Inc | N/A |
| Not Yet Recruiting | Are There Sleep-related Factors That Contribute to an Increased Incidence of Pre-eclampsia at Altitude? NCT06702475 | University of Colorado, Denver | — |
| Recruiting | A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpa NCT06785116 | University of Michigan | Phase 4 |
| Recruiting | Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History NCT06821685 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Phase 1 |
| Unknown | co Ihibtory Receptor in Preeclampsia NCT05294952 | Assiut University | Phase 4 |
| Recruiting | Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy NCT06523569 | Northwestern University | N/A |
| Recruiting | PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients) NCT07263490 | Copenhagen University Hospital, Hvidovre | — |
| Completed | Brain Health in Midlife NCT06640842 | University of Kansas Medical Center | — |
| Not Yet Recruiting | Prevalence of Blood Pressure Complications During Cesarean Section in Pre-eclamptic Patients (HOPE) NCT06588023 | University Hospital, Clermont-Ferrand | — |
| Enrolling By Invitation | Acute Beetroot Juice Supplementation in Pre-eclampsia Pregnancies NCT06387784 | University of Sao Paulo | N/A |
| Recruiting | Inferior Vena Cava Collapsibility Index Guide for Preoperative Fluid Therapy in Preeclampsia NCT06539026 | Ain Shams University | N/A |
| Not Yet Recruiting | Preeclampsia Intervention Netherlands NCT06452498 | Amsterdam UMC | Phase 3 |
| Recruiting | Ultrasound Airway Assessment of Critically Ill Preeclamptic; Comparison Between Two Technique NCT06651879 | Ain Shams University | N/A |
| Recruiting | Physical Activity to Mitigate PreEclampsia Risk NCT06319014 | East Carolina University | N/A |
| Recruiting | APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia NCT06408181 | University of Pennsylvania | Phase 3 |
| Not Yet Recruiting | Role of Vaspin in Pathophysiology of Pre-eclampsia NCT06437535 | Assiut University | — |
| Recruiting | Treatment With Aspirin After Preeclampsia: TAP Trial NCT06281665 | Malamo Countouris | Phase 4 |
| Unknown | Classical Turkish Music for Pregnant Women With Preeclampsia NCT06315985 | Tarsus University | N/A |
| Recruiting | LEARNER- Low dosE AspiRiN prEterm tRial (Angola) NCT06417411 | Instituto Nacional de Investigacao em Saude, Angola | Phase 1 / Phase 2 |
| Recruiting | Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China NCT06414655 | Peking University Third Hospital | — |
| Completed | Homocysteine in Critically Ill Preeclampsia NCT06413576 | Ain Shams University | — |
| Recruiting | Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women NCT06180811 | Christiana Care Health Services | N/A |
| Recruiting | Screening for Preeclampsia in Norway With Aspirin Discontinuation at 24-28 Weeks NCT06108947 | St. Olavs Hospital | N/A |
| Active Not Recruiting | Hydroxychloroquine May be Beneficial for Preeclampsia NCT06020378 | RenJi Hospital | — |
| Recruiting | Multi-Omics for Maternal Health After Preeclampsia NCT06340152 | University of California, San Diego | — |
| Completed | Optimal Blood Pressure Treatment Thresholds Postpartum NCT06069102 | Alisse Hauspurg | Phase 4 |
| Completed | Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns NCT06653374 | HOSPITAL GINECO OBSTETRICO ISIDRO AYORA | — |
| Recruiting | Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obe NCT06067906 | Centre Hospitalier le Mans | N/A |
| Recruiting | Role of Anti-C1q Autoantibodies in Pregnancy NCT06317467 | IRCCS Burlo Garofolo | — |
| Terminated | CONNEQT Pulse Validation Study NCT06002971 | Mount Carmel Health System | — |
| Recruiting | Vascular Biomarkers Predictive of the Progression From Hypertensive Disorders in Pregnancy to Preeclampsia in NCT04520048 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology NCT05625724 | University Hospital, Toulouse | Phase 3 |
| Unknown | Low Dose Aspirin for Prevention of Early Pregnancy Loss NCT06261203 | Egymedicalpedia | N/A |
| Recruiting | Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial NCT05655936 | University of Pittsburgh | N/A |
| Recruiting | Pilot Study of Microvesicles in Pre-eclamptic and Non-pre-eclamptic Women With Threatened Preterm Delivery NCT05675969 | University Hospital, Bordeaux | N/A |
| Completed | sFlt-1/PlGF Ratio: Impact on the Management of Patients With Suspected Pre-eclampsia NCT05228002 | Centre Hospitalier Universitaire de Nice | N/A |
| Completed | BH4 Blood Levels Variations in Pre Eclamptic Women NCT05847361 | University Tunis El Manar | — |
| Unknown | Body Fat Index for Obstetric Risk Stratification NCT05533996 | Assiut University | N/A |
| Completed | Evaluation of HALP Score in Preeclampsia NCT05816044 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Recruiting | At High-risk for Pre-eclampsia After Assisted Reproductive Technology NCT05746793 | CRG UZ Brussel | — |
| Completed | Serpin C and Soluble Fms-like Tyrosine Kinase-1 Levels in Normotensive Pregnant Women May Predict the Developm NCT06214702 | Benha University | — |
| Completed | Maternal Serum Stathmin-1 Levels in Preeclampsia NCT06623955 | Başakşehir Çam & Sakura City Hospital | — |
| Completed | Prostasin Levels in Preeclamptic Women NCT06623942 | Başakşehir Çam & Sakura City Hospital | — |
| Completed | Midkine Role With Deregulated Oxidative and Immune Milieu in Induction of Preeclampsia NCT06329284 | Benha University | N/A |
| Unknown | Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women NCT05622838 | Assiut University | — |
| Unknown | State of Coagulation in Pre-eclampsia: Comparing Sonoclot Signature Analysis With Conventional and Specific Ha NCT05625763 | Assiut University | — |
| Completed | Vital Mechanism of NETs Formation vs. Suicidal Mechanism of NETs Formation During Normal Pregnancy and Preecla NCT05470712 | Centre Hospitalier Universitaire de Nīmes | — |
| Enrolling By Invitation | LMWH for Treatment of Early Fetal Growth Restriction (HepaGrowth) NCT04762992 | Centro Hospitalar de Lisboa Central | Phase 3 |
| Unknown | Select Nutrient and Gene Variant Analysis in a Targeted Diet and Lifestyle Intervention Reduces Preterm Birth NCT05436119 | GrowBaby Life Project | — |
| Completed | SMART Health Pregnancy 2 - Intervention to Reduce Anaemia and Cardiometabolic Risk During Pregnancy and in the NCT05752955 | The George Institute | N/A |
| Recruiting | PEPPI Study: Identification of Women at Risk for Placental Dysfunction NCT06115122 | Oulu University Hospital | — |
| Completed | Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia. NCT05703802 | University Hospital Muenster | — |
| Completed | Autogenic Training Effects on Pre-eclampsia NCT05709834 | Riphah International University | N/A |
| Not Yet Recruiting | Study of Pregnancy Pathologies Associated With Placental Abnormalities NCT05188066 | University Hospital, Grenoble | — |
| Completed | The Role of Pentraxin 3 and Cathepsin B Levels in Preeclamptic Pregnancy NCT05924061 | Sanliurfa Mehmet Akif Inan Education and Research Hospital | — |
| Unknown | Cardiac Output Monitoring to Predict Pre-Eclampsia and Restricted Growth (COMPaRE) NCT05123677 | Sandwell & West Birmingham Hospitals NHS Trust | — |
| Unknown | Labor Induction in Preeclampsia High-risk Women NCT05056467 | Chinese University of Hong Kong | N/A |
| Recruiting | Early Prediction of Preeclampsia Using arteriaL Stiffness in High-risk prEgnancies NCT04783597 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Completed | Neonatal Sleep Intervention to Improve Postpartum Hypertension NCT04864249 | Alisse Hauspurg | N/A |
| Terminated | Prospective Case-Control Study of Cardiovascular Changes in Pregnancy Related Hypertensive Disorders NCT04713228 | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | N/A |
| Unknown | Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies NCT05434195 | University of Oxford | N/A |
| Unknown | Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia NCT03838887 | National Research Centre, Egypt | — |
| Unknown | Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension NCT04908982 | Eastern Virginia Medical School | Phase 4 |
| Unknown | Factors Predicting Transformation of Non Severe Pre-eclampsia Into Pre-eclampsia With Severe Features NCT05152550 | Ahmed Nagy Abdul-Rahman Younis | — |
| Completed | Midazolam Efficacy/Safety in Pre-Eclamptic C-Section Sedation NCT07021521 | Zhuji People's Hospital of Zhejiang Province | N/A |
| Unknown | Cardiovascular Changes in Infants of Preeclampsia Mother NCT04699825 | Assiut University | N/A |
| Unknown | Breastfeeding and Postpartum Cardiovascular Health NCT04580927 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Unknown | The Effectiveness of Aspirin on Preventing Pre-eclampsia NCT04656665 | The Third Affiliated Hospital of Guangzhou Medical University | Phase 4 |
| Completed | Placental Volume, Flow, and Vascularity Study NCT04900207 | University of Minnesota | — |
| Unknown | Precision Medicine for Prediction & Prevention of Early Pre-eclampsia NCT04412681 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | Preeclampsia Sequential Screening Using Angiogenic Factors During First Trimester of Pregnancy NCT04767438 | Instituto de Investigación Sanitaria Aragón | — |
| Recruiting | Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy NCT04356326 | Centre Hospitalier Intercommunal Creteil | Phase 3 |
| Terminated | Metformin and Esomeprazole in Preterm Pre-eclampsia NCT06359015 | Christiana Care Health Services | Phase 4 |
| Unknown | Development of Intervention for Women After Gestational Diabetes or Pre-eclampsia NCT04716244 | Hadassah Medical Organization | — |
| Completed | Furosemide vs. Placebo for Severe Antepartum Hypertension NCT04615624 | Melanie Maykin, MD | Phase 3 |
| Completed | Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiog NCT05299229 | Yale University | — |
| Unknown | Comparing the Incidence of Preeclampsia Between Pregnant Women Receiving Tdap Vaccinations at Week 28 or at We NCT04424693 | Institute of Arthritis Research | Phase 4 |
| Recruiting | Bioimpedence and Arterial Function Monitoring at Birth and in Infants NCT04720690 | Imperial College Healthcare NHS Trust | — |
| Unknown | Natural Cycle or Stimulated Cycle Versus Hormone Replaced Cycle for Pre-eclampsia Rate NCT04310683 | Women's Hospital School Of Medicine Zhejiang University | N/A |
| Completed | The Effect of Foot Massage on Blood Pressure and Anxiety Levels in Pregnants With Hypertension NCT05542654 | Bandırma Onyedi Eylül University | N/A |
| Unknown | The BEET-BP Trial - Investigating the Effect of Dietary Nitrates on Hypertension in Pregnancy NCT04604535 | King's College Hospital NHS Trust | N/A |
| Completed | Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes NCT04633551 | University of South Carolina | N/A |
| Active Not Recruiting | Natural Versus Programmed Frozen Embryo Transfer (NatPro) NCT04551807 | JHSPH Center for Clinical Trials | Phase 3 |
| Completed | Prenatal Yoga as Complementary Therapy of Preeclampsia NCT04795154 | Indonesia University | N/A |
| Terminated | Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE) NCT04402385 | Yale University | Phase 2 |
| Unknown | Xanthine Oxidase and Uric Acid Origin in Preeclamptic Women NCT04463940 | Barzilai Medical Center | — |
| Unknown | Vitamin D in Pregnancy NCT04291313 | University of Aarhus | N/A |
| Unknown | Inter- and Multidisciplinary, Cross-sectoral Feto-neonatal Pathway NCT04514276 | Technische Universität Dresden | N/A |
| Completed | Early Onset Preeclampsia and Nectin-4 NCT05098691 | Hatice Akkaya | — |
| Unknown | Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia NCT04287998 | Assiut University | — |
| Completed | Comparative Study for the Validity of Various Severity Scoring System NCT04683094 | Aswan University Hospital | — |
| Active Not Recruiting | Physician Optimised Post-partum Hypertension Treatment Trial NCT04273854 | University of Oxford | N/A |
| Completed | Lifestyle Intervention for Women With Recent Pre-eclampsia or Gestational Diabetes Mellitus ('Mom's Healthy He NCT03993145 | Norwegian University of Science and Technology | N/A |
| Completed | Preeclamptic Patients and Pentraxin 3 & Lipoprotein-associated Phospholipase A2 NCT04239352 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Completed | Measuring Practice Pattern Changes and Clinical Utility of a Novel Test for Preeclampsia NCT04204018 | Qure Healthcare, LLC | N/A |
| Completed | MRI Angiography of Physiological and Pathological Pregnancy Placentas Ex-vivo NCT04389099 | Central Hospital, Nancy, France | — |
| Unknown | Interest of sFlt1/PlGF Ratio at Obstetric Emergencies NCT04170660 | Centre Hospitalier Intercommunal Creteil | — |
| Completed | qMOLI- A Qualitative Assessment of Misoprostol or Oxytocin for Labour Induction NCT04037683 | University of Liverpool | — |
| Unknown | sFlt-1:PlGF Ratio in Gestational Diabetes: PREDICTION (PREeclampsia in DIabetiC gestaTION) Study NCT04877119 | Azienda Ospedaliero, Universitaria Pisana | — |
| Completed | IMPACT OF THE BIOLOGICAL RATIO ON MEDICAL DECISION MAKING IN WOMEN SUSPECTED OF PREECLAMPSIA NCT06224946 | Centre Hospitalier Universitaire de Saint Etienne | — |
| Completed | Optic Nerve Sheath Diameter for Volume Status Prediction in Severe Preeclampsia NCT04367519 | Zagazig University | — |
| Completed | SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in R NCT03968952 | University of Oxford | N/A |
| Terminated | Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer NCT04092829 | Instituto Valenciano de Infertilidad, IVI VALENCIA | N/A |
| Unknown | Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial NCT03302260 | University of Calgary | N/A |
| Unknown | Preeclampsia Associated Vascular Aging NCT04484766 | Jena University Hospital | — |
| Completed | An mHealth Strategy to Reduce Pre-Eclampsia and Infant Death in Tanzania NCT03978429 | Dr. Karen Yeates | N/A |
| Completed | Detection of False Positives From First-trimester Preeclampsia Screening (StopPRE) at the Second-trimester of NCT03741179 | Hospital Universitari Vall d'Hebron Research Institute | Phase 3 |
| Unknown | Fetal Autonomic Nervous sysTem Evaluation NCT06330987 | University of Pisa | — |
| Completed | Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST) NCT03941886 | Chiu Yee Liona Poon | N/A |
| Completed | Optic Nerve Sheath Diameter in Preeclampsia NCT04004897 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Unknown | Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level NCT03928691 | Assiut University | — |
| Unknown | Clinical Effectiveness of First Trimester Pre-eclampsia Screening Program. NCT04021680 | Far Eastern Memorial Hospital | — |
| Unknown | Pre-eclampsia and Future Cardiovascular Health: An Underused Opportunity to Improve Family Health NCT04676295 | Helsinki University Central Hospital | N/A |
| Completed | Association Between Pococyturia and Pre-eclampsia Severity NCT03316391 | Hospices Civils de Lyon | — |
| Active Not Recruiting | The CoPenHagen PREeClampsia and cardIOvascUlar diSease Study NCT03949829 | Klaus Fuglsang Kofoed | — |
| Completed | Podocyturia as Predictive Factor for Pre-eclampsia NCT03316430 | Hospices Civils de Lyon | — |
| Completed | Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida NCT03961360 | The University of Texas Health Science Center, Houston | Phase 2 / Phase 3 |
| Unknown | Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia NCT03917342 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia NCT03893630 | John O'Brien, MD | Phase 2 |
| Unknown | Vitamin D Level and Its Relation to Pre-eclampsia and Eclampsia NCT03882099 | Cairo University | — |
| Completed | Understanding Post-translational Modifications to Circulating Histones Via Mass Spectrometry in Pregnant Women NCT05142410 | Centre Hospitalier Universitaire de Nīmes | — |
| Unknown | Maternal and Neonatal Outcome in Severe Preeclampsia NCT04126122 | Aljazeera Hospital | — |
| Completed | Maternal Serum Markers Predicting Preeclampsia At Early Gestations NCT05131282 | HBI Solutions Inc. | — |
| Unknown | Management of Suspected Preeclampsia Based on 6-hour Versus 24-hour Urine Protein Collection NCT03724786 | Wolfson Medical Center | N/A |
| Unknown | Diagnostic Value of MicroRNA 210 In Preeclampsia NCT03193554 | Assiut University | — |
| Unknown | Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in NCT03112551 | Gadarif University | N/A |
| Unknown | Metformin and Esomeprazole in Treatment of Early Onset Preeclampsia NCT03717701 | Aswan University Hospital | N/A |
| Unknown | Esomeprazole for the Prevention of Preeclampsia NCT03717740 | Aswan University Hospital | Phase 3 |
| Completed | Acute Exercise Effects in Obese Pregnancy NCT03750695 | Duke University | N/A |
| Recruiting | Mechanisms of Pregnancy Vascular Adaptations NCT03806283 | University of Wisconsin, Madison | — |
| Completed | Study for Improving Maternal, Pregnancy and Child Outcomes NCT03831490 | Uppsala University | — |
| Unknown | Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women NCT03767803 | Progenity, Inc. | — |
| Withdrawn | Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women NCT03196141 | Yale University | N/A |
| Unknown | Predictors of Intrauterine Growth Restriction NCT03349671 | Assiut University | — |
| Completed | Placental Growth Factor as a Predictor of Adverse Pregnancy Outcomes in Preeclamptic Women NCT04374604 | Johnbosco Ifunanya Nwafor | — |
| Unknown | TTP and aHUS in Complicated Pregnancies NCT03605511 | University College, London | — |
| Completed | C1q/TNF-related Protein 9 (CTRP 9) Level in Preeclamptic Obese and Non-obese Pregnancies NCT03650790 | Diyarbakir Women's and Children's Diseases Hospital | N/A |
| Unknown | Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection NCT03626233 | Centre Hospitalier Intercommunal Creteil | — |
| Unknown | Evaluation of Neutrophil/Lymphocyte Ratio ,Platelet/Lymphocyte Ratio and CRP as Markers of Severity of Pre-ecl NCT03630276 | Ain Shams University | N/A |
| Completed | ASA Patterns for Prevention of Preeclampsia in SLE Pregnancies NCT03749044 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler NCT03342014 | Central Hospital, Nancy, France | N/A |
| Unknown | Indonesia Pravastatin to Prevent Preeclampsia Study NCT03648970 | Universitas Airlangga | Phase 2 |
| Completed | Prediction of Preeclampsia by Comprehensive Markers. NCT03665623 | Peking Union Medical College Hospital | — |
| Completed | Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension NCT03334149 | University of Oxford | N/A |
| Unknown | Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide NCT03298802 | The University of Texas Medical Branch, Galveston | Phase 3 |
| Completed | Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients. NCT03515759 | Cairo University | — |
| Completed | Study of Nicotinamide in Early Onset Preeclampsia NCT03419364 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Effects of Diet on Pregnancy Outcome and Child Obesity NCT03232762 | NYU Langone Health | N/A |
| Unknown | Correlation Between Changes in Liver Stiffness and Preeclampsia as Shown by Fibroscan NCT03299777 | Western Galilee Hospital-Nahariya | — |
| Completed | Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery NCT03252496 | Mansoura University | N/A |
| Unknown | Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy NCT03214393 | Cairo University | — |
| Completed | Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child) NCT03269110 | Ottawa Hospital Research Institute | — |
| Completed | Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia NCT02881073 | Irish Centre for Fetal and Neonatal Translational Research | N/A |
| Completed | Peri-operative Dexmedetomidine Infusion in Pre-eclamptic Patients NCT03391609 | Assiut University | Phase 2 / Phase 3 |
| Unknown | Vascular Changes in Pre-Eclamptic Patients and Its Impact on Pregnancy Outcome. NCT03111576 | Beni-Suef University | — |
| Unknown | Catestatin and Hypertension in Pregnancy NCT03200743 | Yuchen Pan | — |
| Completed | Evaluation of Electrical Velocimetry for Assessment of Extra-vascular Lung Water in Pre-eclamptic Patients NCT03127865 | Cairo University | — |
| Unknown | Preeclampsia Research on Vitamin D, Inflammation, & Depression NCT03018132 | Cedars-Sinai Medical Center | N/A |
| Completed | Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for P NCT02801695 | Nantes University Hospital | Phase 2 / Phase 3 |
| Completed | Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascul NCT03455387 | Centre Hospitalier Metropole Savoie | — |
| Completed | Prediction of Preeclampsia (PE) at 11-13 Week NCT03554681 | Chiu Yee Liona Poon | — |
| Completed | The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy NCT02891174 | University of Michigan | Phase 4 |
| Completed | PREPARE, Prematurity Reduction by Pre-eclampsia Care NCT03073317 | Instituto Fernandes Figueira | N/A |
| Completed | PREDICTION OF FLUID RESPONSIVENESS WITH PASSIVE LEG RISING IN PREGNANT PATIENTS WITH SEVERE PREECLAMPSIA NCT03755843 | RAUL CARRILLO ESPER | — |
| Completed | Screening and Treatment of Obstructive Sleep Apnea in High-risk Pregnancy NCT03356106 | Ramathibodi Hospital | N/A |
| Recruiting | PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis NCT05500989 | Maastricht University Medical Center | — |
| Completed | Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features NCT02911701 | University of New Mexico | Phase 4 |
| Unknown | Impact of Antichlamydial Treatment on the Rate of Preeclampsia NCT03233880 | Ain Shams Maternity Hospital | Phase 4 |
| Unknown | Prediction of Early Pre-eclampsia From Maternal Factors, Biophysical and Biochemical Markers at First Trimeste NCT02990767 | Shanghai First Maternity and Infant Hospital | — |
| Unknown | Women Specific Cardiac Recovery After Preeclampsia NCT02807324 | Maastricht University Medical Center | — |
| Recruiting | LimPrOn: Limburg Pre-eclampsia Investigation NCT03509272 | Hasselt University | N/A |
| Completed | Adipokines, Inflammation, Insulin Resistance and Endothelial Dysfunction in Preeclampsia NCT04455204 | Tanta University | — |
| Unknown | Dietary Intervention Program for Pre-eclampsia in Women at Risk NCT02706158 | Rambam Health Care Campus | N/A |
| Completed | Acid-Base and Point of Care Ultrasound in Severe Preeclampsia NCT02721771 | University of Cape Town | — |
| Unknown | CA-125 and Severity of Pre-Eclampsia NCT02704676 | Ain Shams Maternity Hospital | — |
| Completed | Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia NCT02992145 | Ain Shams Maternity Hospital | — |
| Terminated | Saccadic Reaction Time and Preterm Pre-eclampsia NCT02613793 | Oxford University Hospitals NHS Trust | — |
| Completed | Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia NCT03028194 | Saint Thomas Hospital, Panama | N/A |
| Completed | Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana NCT02468310 | Hannah Brown Amoakoh | N/A |
| Completed | Free DNA and Nucleosome Concentrations in Pathological Pregnancies NCT01736826 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study NCT02677233 | Ain Shams Maternity Hospital | — |
| Completed | Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Pregnant Women NCT02319174 | William Marsh Rice University | N/A |
| Terminated | Non-invasive Versus Invasive Blood Pressure Measurement in the Morbidly Obese Parturient With Severe Preeclamp NCT03222414 | Vanderbilt University Medical Center | N/A |
| Completed | Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study NCT02333240 | University of Oxford | N/A |
| Completed | Pilot Assessment of an Auto Blood Pressure Monitor NCT02258256 | William Marsh Rice University | N/A |
| Completed | Assessment of a Syringe Pump to Pre-eclamptic Women in a Low-resource Hospital NCT02296931 | William Marsh Rice University | Phase 1 / Phase 2 |
| Completed | Thoracic Ultrasonography for Pulmonary Edema in Patients With Pre-Eclampsia NCT02357264 | Antonios Likourezos | — |
| Completed | Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Adult Volunteers NCT02267577 | William Marsh Rice University | N/A |
| Unknown | Early Vascular Adjustments During Hypertensive Pregnancy NCT02531490 | Maastricht University Medical Center | Phase 4 |
| Unknown | Heart Failure and Related Risk-factors After Preeclampsia NCT02347540 | Maastricht University Medical Center | — |
| Completed | Low Dose Calcium to Prevent Preeclampsia NCT02338687 | Federal University of São Paulo | Phase 4 |
| Completed | ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes NCT02218931 | Queen Mary University of London | N/A |
| Terminated | Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia NCT03863639 | Duke University | — |
| Terminated | Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes. NCT02174328 | Instituto de Investigacion Sanitaria La Fe | Phase 3 |
| Completed | Trial of Early Screening Test for Pre-eclampsia and Growth Restriction NCT03674606 | University College Dublin | Phase 4 |
| Completed | Restrictive Fluid Therapy in Severe Preeclampsia NCT02214186 | University of Sao Paulo General Hospital | N/A |
| Completed | Neurobehavioural Outcomes in Late Preterm Neonates NCT02443259 | Lady Hardinge Medical College | — |
| Completed | Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design NCT03151070 | Hospital San Juan de Dios Guatemala | — |
| Completed | Induction With Foley OR Misoprostol (INFORM) Study NCT01801410 | University of Liverpool | Phase 3 |
| Unknown | IMproved PRegnancy Outcome by Early Detection NCT01891240 | Louise Kenny | — |
| Completed | Community Level Interventions for Pre-eclampsia NCT01911494 | University of British Columbia | N/A |
| Completed | New Magnesium Sulphate Protocol for Pre-eclampsia NCT01846156 | Cairo University | Phase 3 |
| Terminated | Safety and Efficacy of RLX030 in Pregnant Women With Pre- Eclampsia NCT01566630 | Novartis Pharmaceuticals | Phase 2 |
| Unknown | Oxfordshire Women and Their Children's Health NCT02419898 | Oxford University Hospitals NHS Trust | — |
| Completed | Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. NCT02050529 | Dow University of Health Sciences | Phase 2 |
| Completed | Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia NCT03101150 | King Fahad Medical City | Phase 1 / Phase 2 |
| Terminated | Phenylephrine Versus Ephedrine in Pre-eclampsia NCT02025426 | Duke University | Phase 4 |
| Completed | Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE) NCT01480544 | Duke University | N/A |
| Completed | A Modernized Approach to Prenatal Care in Low Risk Women NCT01606774 | Massachusetts General Hospital | N/A |
| Completed | Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Ute NCT01729468 | University Hospital, Tours | Phase 4 |
| Completed | D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life NCT03330301 | Bispebjerg Hospital | — |
| Withdrawn | Progesterone for First Trimester Vaginal Bleeding NCT01501890 | Soroka University Medical Center | N/A |
| Completed | FACT Biomarker Subgroup Analysis NCT03981029 | Ottawa Hospital Research Institute | — |
| Completed | Can Atorvastatin Improve Vascular Function in Women With a History of Preeclampsia? NCT01278459 | University of Oxford | Phase 3 |
| Completed | Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia NCT01352234 | CHU de Quebec-Universite Laval | Phase 4 |
| Completed | EG-VEGF : Potential Marker of Pre-eclampsia and / or Intrauterine Growth Restriction NCT01490489 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Unknown | Random Urine Protein-creatinin Ratio to Predict Magnitude of Proteinuria NCT01623791 | Cukurova University | — |
| Completed | Goal-Directed Therapy in Pregnant Women at High Risk of Developing Preeclampsia NCT01351428 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Sleep Apnea Syndrome in Obese Women During Pregnancy NCT03509805 | University Hospital, Lille | N/A |
| Terminated | A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Preg NCT01193192 | Pamlab, L.L.C. | — |
| Completed | Study of Coagulation Activation Markers and Pre Eclampsia NCT01261351 | University Hospital, Lille | — |
| Completed | Evaluation of the Effectiveness of Vitamin D Supplementation to Pregnant Women and Their Infants in Pakistan. NCT01229189 | Aga Khan University | N/A |
| Completed | Placental Growth and Adverse Pregnancy Outcomes NCT01669525 | University of Pennsylvania | — |
| Unknown | Establishing First Trimester Markers for the Identification of High Risk Twin NCT02031393 | Assaf-Harofeh Medical Center | — |
| Completed | Observational Study in UTERO - Placental 3D Doppler Examination: Interest for Pre-eclampsia Screening During P NCT00930397 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study) NCT00865683 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 1 |
| Withdrawn | Investigating the Novel Observation of Right-left Difference in Uterine Artery Vascular Resistance in Pre-ecla NCT00848679 | Hadassah Medical Organization | Phase 3 |
| Unknown | Pre-Eclampsia Prediction By Doppler Screening Of Uterine Arteries And Angiogenic Factors In Second Trimester O NCT00725660 | Shaare Zedek Medical Center | — |
| Unknown | Remifentanil for General Anesthesia in Preeclamptics NCT00567957 | Istanbul University | Phase 4 |
| Completed | Assessment of Physical Exercise Using Stationary Bicycle for Pregnant Women With Risk for Preeclampsia Develop NCT01395342 | University of Campinas, Brazil | Phase 1 |
| Completed | Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications NCT00485784 | Assistance Publique Hopitaux De Marseille | N/A |
| Terminated | Early Placental Insufficiency Screening NCT01348711 | University Hospital, Tours | — |
| Suspended | Evaluation of the Safety of Relaxin in Preeclampsia NCT00333307 | Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies | Phase 1 |
| Completed | Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor NCT01140971 | Municipal Hospital Vila Nova Cachoeirinha | N/A |
| Unknown | Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence NCT00262093 | Hadassah Medical Organization | — |
| Unknown | Prevention of Pre-Term Birth by Treatment of Periodontal Disease NCT00133926 | King Edward Memorial Hospital | Phase 2 |
| Completed | Disease Modification in Toxaemia of Pregnancy NCT00175695 | University of British Columbia | — |
| Terminated | Sildenafil Citrate for the Treatment of Established Pre-Eclampsia NCT00141310 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 2 |
| Completed | The Relaxation and Blood Pressure in Pregnancy (REBIP) Study NCT00303173 | University of Toronto | N/A |
| Completed | Efficacy Study of Digibind for Treatment of Severe Preeclampsia NCT00158743 | BTG International Inc. | Phase 2 |
| Unknown | Prospective Study in Pregnant Women With Hypercoagulopathy NCT00215969 | Hillerod Hospital, Denmark | — |
| Completed | Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclam NCT00197340 | Hadassah Medical Organization | Phase 3 |
| Completed | HMW-Adiponectin is Raised in Newborns NCT00438542 | University of Oslo | — |
| Completed | Doppler and Biological Second Trimester Placental Insufficiency Screening NCT00465634 | University Hospital, Tours | — |
| Completed | L-Arginine in Pre-Eclampsia NCT00157521 | Mario Negri Institute for Pharmacological Research | Phase 3 |
| Terminated | L-Arginine and Antioxidant Vitamins During Pregnancy to Reduce Preeclampsia NCT00469846 | Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes | Phase 2 |
| Completed | Measuring Blood Pressure in Pregnancy Using Mercury and Automated Device NCT00809666 | St George Hospital, Australia | N/A |
| Completed | Glomerular Injury of Preeclampsia NCT00275158 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | N/A |
| Completed | Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients Wi NCT00004399 | FDA Office of Orphan Products Development | N/A |
| Completed | Angiotensinogen Variants and Adverse Pregnancy Outcomes NCT00005400 | University of Utah | — |
| Completed | Oral Calcium in Pregnant Women With Hypertension NCT00000543 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | Calcium for Pre-Eclampsia Prevention (CPEP) NCT00000534 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 3 |
| Completed | Hypertensive and Normal Pregnancy--Calcium Metabolism and Renin-Angiotensin - SCOR in Hypertension NCT00005456 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Renin and Prorenin in Pregnancy NCT00005207 | National Heart, Lung, and Blood Institute (NHLBI) | — |