Trials / Unknown
UnknownNCT00262093
Angiogenesis Markers in Primiparas Versus Multiparas: Relevance to Preeclampsia Incidence
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (estimated)
- Sponsor
- Hadassah Medical Organization · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Accepted
Summary
The reason for having a higher incidence of preeclampsia in primiparas may involve angiogenesis imbalance in these patients.
Detailed description
Primiparity is one of the main risk factors for having preeclampsia during pregnancy. Recently, sFlt-1, soluble FMS-like tyrosine kinase-1, has been shown to be a major molecule involved in the pathogenesis of preeclampsia. Higher sFlt-1 mRNA, higher serum levels of sFlt-1 as well as lower PlGF, placental growth factor, have been found in preeclamptic patients. We intend to check the angiogenesis profile of primiparas as compared to multiparas.
Conditions
Timeline
- Start date
- 2005-11-01
- First posted
- 2005-12-06
- Last updated
- 2007-03-20
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT00262093. Inclusion in this directory is not an endorsement.