NCT03838887

Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: National Research Centre, Egypt · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

• Preeclampsia is a multisystem disorder that can cause considerable maternal and fetal morbidity and mortality. Late preeclampsia (with delivery \>34 weeks) is more frequent and less serious than early preeclampsia (with delivery \<34 weeks). Poor early placentation has been especially associated with early disease. Early identification of women at risk of preeclampsia is currently a crucial aim of antenatal care since they may benefit from prophylactic treatment and increased surveillance.

Detailed description

* The introduction of three-dimensional (3D) ultrasound techniques, with the option of calculating placental volume and measuring vascular indices, has created an excellent opportunity to study early changes in the uteroplacental circulation space, which includes the maternal spiral arteries and the intervillous space. This technology may allow a more direct evaluation of the abnormal placentation process thought to herald the development of preeclampsia. * The aim of this study was to assess the usefulness of placental volume and 3D vascular indices as reliable predictors of early preeclampsia in comparison to uterine artery Doppler

Conditions

• Pre-Eclampsia

Interventions

Type	Name	Description
DEVICE	ultrasound machine	Ultrasound machine with a vocal software

Timeline

• Start date: 2021-06-01
• Primary completion: 2021-12-01
• Completion: 2022-01-01
• First posted: 2019-02-12
• Last updated: 2021-08-18

Locations

1 site across 1 country: Egypt