NCT03724786

Management of Suspected Preeclampsia Based on 6-hour Versus 24-hour Urine Protein Collection

Management of Pregnancies With Suspected Preeclampsia Based on 6-hour Versus 24-hour Urine Protein Collection - a Randomized Double Blind Controlled Pilot Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Wolfson Medical Center · Other Government
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

In this trial - the investigators plan to study the efficacy of pregnancy management in cases of suspcted preeclampsia, based on a 6-hour urine collection for protein, as compared to the standard 24-hour collection. For participants hospitalized at the maternal fetal unit at our institution, one sample of urine collected over 6 hours will be analyzed, and a second one following an additional 18 hours. Participants will be blinded to the urine collection result used to manage their pregnancy (actual 24 hour collection versus calculated 24-hour collection), as will be their attending physicians. An external physician will compare the two urine collection results, and in case only one is pathological (\>300 mg), will notify the research team and the attending physician.

Conditions

• Pre-Eclampsia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Six-hour urine protein collection	This intervention includes the analysis of a 6-hour urine collection for protein, to serve for a calculated 24-hour result, according to which pregnancy will be managed.

Timeline

• Start date: 2019-01-01
• Primary completion: 2021-07-01
• Completion: 2021-07-01
• First posted: 2018-10-30
• Last updated: 2020-10-08

Locations

1 site across 1 country: Israel