Clinical Trials Directory

Trials / Sponsors / FDA Office of Orphan Products Development

FDA Office of Orphan Products Development

Federal · 32 registered clinical trials.

StatusTrialPhaseStarted
WithdrawnPenicillamine Chelation for Children With Lead Poisoning
Lead Poisoning, Vitamin D Deficiency
Phase 2 / Phase 32007-09-01
CompletedA Controlled Study of Olanzapine in Children With Autism
Autistic Disorder
Phase 22003-05-01
CompletedAssessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridine
Guillain-Barre Syndrome
Phase 22002-09-01
CompletedMycophenolate Mofetil in Myasthenia Gravis
Myasthenia Gravis
Phase 32002-09-01
CompletedRisk-adapted Therapy for Primary Systemic (AL) Amyloidosis
Amyloidosis
Phase 22002-09-01
CompletedTesting of ADI-PEG in Hepatocellular Carcinoma
Carcinoma, Hepatocellular
Phase 22002-09-01
CompletedAn Implant for Hearing Loss Due to Removal of Neurofibromatosis 2 Tumors
Neurofibromatosis 2
Phase 12001-09-01
CompletedMinocycline in Patients With Huntington's Disease
Huntington's Disease
Phase 1 / Phase 22001-09-01
CompletedEtanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation
Respiratory Distress Syndrome, Adult, Bronchiolitis Obliterans, Pneumonia
Phase 1 / Phase 22001-09-01
CompletedStudy of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD)
Muscular Dystrophies
N/A2001-09-01
CompletedADI-PEG in Patients With Metastatic Melanoma
Melanoma, Neoplasm Metastasis
Phase 12001-09-01
CompletedKeratinocyte Growth Factor to Prevent Acute GVHD
Graft-vs-Host Disease
Phase 1 / Phase 22001-09-01
CompletedRandomized Study of Recombinant Human Growth Hormone in Patients on Chronic Hemodialysis or Peritoneal Dialysi
Kidney Failure, Chronic
N/A1999-12-01
CompletedRandomized Study of New Formulation Ophthalmic Cysteamine Hydrochloride for Corneal Cystine Accumulation in Pa
Cystinosis
N/A1999-12-01
CompletedPhase III Randomized Study of Interferon Gamma in Children With Severe, Congenital Osteopetrosis
Osteopetrosis
Phase 31999-11-01
CompletedPhase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibroma
Neurofibromatosis 2
Phase 21999-10-01
UnknownPhase III Study of Chondrocyte Alginate Gel Suspension in Pediatric Patients With Vesicoureteral Reflux
Vesicoureteral Reflux
Phase 31999-05-01
CompletedRandomized Study of Beta Interferon and Thalidomide in Patients With Adrenoleukodystrophy
Adrenoleukodystrophy
N/A1998-08-01
CompletedShort Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism
Hyperinsulinism
N/A1998-05-01
CompletedPhase I Randomized Study of CPX for the Treatment of Adult Patients With Mild Cystic Fibrosis
Cystic Fibrosis
Phase 11997-09-01
CompletedStudy of Cysteine Hydrochloride for Erythropoietic Protoporphyria
Erythropoietic Protoporphyria
N/A1996-10-01
CompletedStudy of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis
Cystic Fibrosis
N/A1996-09-01
CompletedStudy of Ibuprofen to Preserve Lung Function in Patients With Cystic Fibrosis
Cystic Fibrosis
N/A1996-08-01
CompletedRandomized Study of Propofol Versus Fentanyl and Midazolam in Pediatric Patients Requiring Mechanical Ventilat
Respiration Disorders
N/A1996-07-01
CompletedPhase III Randomized Study of Anti-Tumor Necrosis Factor Chimeric Monoclonal Antibody (cA2) for Patients With
Crohn's Disease
Phase 31996-07-01
CompletedRandomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients Wi
Pre-eclampsia
N/A1995-09-01
CompletedPhase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosis
Cystic Fibrosis, Bacterial Infection
Phase 31995-06-01
CompletedLiothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedur
Tricuspid Atresia, Heart Defects, Congenital
Phase 11994-12-01
CompletedPilot Randomized Study of Paromomycin (Aminosidine) vs Streptomycin for Uncomplicated Pulmonary Tuberculosis
Tuberculosis, Pulmonary
N/A1994-11-01
CompletedStudy of Gammalinolenic Acid for Juvenile Rheumatoid Arthritis
Juvenile Rheumatoid Arthritis
N/A1994-09-01
CompletedRandomized Study of 3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton Myasthenic Syndrome
N/A1994-08-01
CompletedRandomized Study of Hormonal Regulation of Infantile Hemangioma
Hemangioma
N/A1993-07-01