Clinical Trials Directory

Trials / Completed

CompletedNCT00004420

Study of Gammalinolenic Acid for Juvenile Rheumatoid Arthritis

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
50 (planned)
Sponsor
FDA Office of Orphan Products Development · Federal
Sex
All
Age
1 Year – 15 Years
Healthy volunteers
Not accepted

Summary

OBJECTIVES: I. Determine the efficacy and safety of gammalinolenic acid in the treatment of childhood arthritis.

Detailed description

PROTOCOL OUTLINE: This is a randomized, double blind, placebo controlled, cross over study of 12 months duration. Patients are stratified by type of juvenile rheumatoid arthritis (systemic onset vs pauciarticular disease vs polyarticular disease). Patients are randomized to receive either gammalinolenic acid (GLA) or placebo (safflower seed oil) orally. Parents are asked to maintain the child's usual diet over the course of study. Patients are followed at 3, 6, 9, and 12 months during study and at 6 months thereafter.

Conditions

Interventions

TypeNameDescription
DRUGgamma-Linolenic acid

Timeline

Start date
1994-09-01
Completion
1999-08-01
First posted
1999-10-19
Last updated
2015-03-25

Source: ClinicalTrials.gov record NCT00004420. Inclusion in this directory is not an endorsement.