NCT02992145

Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 80 (actual)
• Sponsor: Ain Shams Maternity Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare between androgens level (serum total and free testosterone) in women with preeclampsia and normal ones in the third trimester of pregnancy (28-40 weeks).

Detailed description

Methodology: All women in this study will be subjected to: * All women are candidates for this study according to inclusion and exclusion criteria. * History taking with special emphases on last menstrual period to determine the exact Gestational age. * A reliable date is defined as the occurrence of regular menstrual cycles (28±7 days) in patients who have not taken oral contraceptives during the three months before conception and have no irregular bleeding. * General and abdominal examination for each patient to determine those patients matching with the inclusion criteria. * Preeclampsia refers to the new onset of hypertension (systolic blood pressure ≥140 mmHg ,or diastolic blood pressure≥ 90 mmHg ,or both, measured on two occasions \> 6 hours apart) and either proteinuria or end organ dysfunction after 20 weeks of gestation in a previously normotensive woman. * At Ain Shams University Hospitals, the investigator will use ELISA based test system intended for the quantitative measurement of total and free testosterone for patients of both groups.

Conditions

• Pre-Eclampsia

Timeline

• Start date: 2016-03-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2016-12-14
• Last updated: 2016-12-16

Locations

1 site across 1 country: Egypt