| Not Yet Recruiting | Ketamine and Dexmedetomidine for Delirium in Joint Arthroplasty NCT06963294 | Istinye University | N/A |
| Not Yet Recruiting | Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentratin NCT07392840 | Minia University | — |
| Not Yet Recruiting | Evaluation of the Ketogenic Diet to Improve Post Operative Cognitive Decline in Cardiac Surgery NCT06480708 | University of Missouri-Columbia | N/A |
| Completed | Minimal-flow Anesthesia and Cognitive Outcomes in Elderly Surgical Patients NCT07424729 | Ankara Etlik City Hospital | N/A |
| Recruiting | Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery NCT07113483 | Romanian Society for Enteral and Parenteral Nutrition | Phase 3 |
| Not Yet Recruiting | Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pedi NCT07192549 | General Hospital of Ningxia Medical University | N/A |
| Recruiting | Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery NCT07452367 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Not Yet Recruiting | The Impact of Remimazolam Tosilate on Oxygenation and Postoperative Cognitive Function in Elderly Patients Und NCT07086911 | Jinqiao Qian | Phase 1 / Phase 2 |
| Recruiting | Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass NCT07000461 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Not Yet Recruiting | Timing of Transcutaneous Acupoint Electrical Stimulation on Postoperative Recovery in Geriatric Patients with NCT05482477 | Subei People's Hospital of Jiangsu Province | N/A |
| Completed | Effect of Pericapsular Nerve Group Block on Postoperative Cognitive Function NCT06736405 | Ankara City Hospital Bilkent | N/A |
| Completed | GDFT and Postoperative Cognitive Function in Geriatric Cancer Surgery NCT07438249 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | — |
| Recruiting | Older People's Neurocognitive Recovery After Cardiac Surgery NCT06469515 | Karolinska Institutet | — |
| Active Not Recruiting | Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder NCT06689137 | Haseki Training and Research Hospital | — |
| Completed | Comparison Between the Effect of Dexmedetomidine _midazolam and ketamine_midazolam Combination NCT07074262 | Beni-Suef University | N/A |
| Completed | The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients NCT06392919 | Affiliated Hospital of Nantong University | N/A |
| Completed | LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients NCT06387836 | Shanghai Zhongshan Hospital | N/A |
| Recruiting | CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State NCT06133842 | Beth Israel Deaconess Medical Center | — |
| Recruiting | Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly NCT06658769 | University of Sao Paulo General Hospital | N/A |
| Completed | The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patient NCT06353516 | Chung-Ang University Gwangmyeong Hospital | N/A |
| Unknown | The Effect of Intraoperative Hypotension on Postoperative Cognitive Functions in Cesarean Section Operations NCT05843838 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Kids With Iron Deficiency and Scoliosis NCT06042699 | Columbia University | N/A |
| Completed | Dexmedetomidine and Postoperative Cognitive Dysfunction (POCD) NCT06371638 | Udayana University | Phase 4 |
| Completed | The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery NCT06655025 | Sohag University | N/A |
| Unknown | Transcranial Magnetic Stimulation and Perioperative Neurocognitive Disorders NCT05668559 | Anshi Wu | N/A |
| Completed | Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunct NCT07509372 | Ankara University | — |
| Recruiting | Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients NCT06176144 | West China Hospital | N/A |
| Recruiting | The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium NCT05990790 | Medical University of Vienna | Phase 4 |
| Recruiting | Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardia NCT05036538 | Heart and Brain Research Group, Germany | N/A |
| Unknown | The Influence of Electroacupuncture on Postoperative Agitation of Pediatrics Undergoing Sevoflurane General An NCT05924854 | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | N/A |
| Unknown | Correlation Between Perioperative EEG Features and Delirium After General Anesthesia NCT06082024 | Fuzhou Hua | — |
| Recruiting | The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study NCT05574400 | University of Michigan | Phase 2 |
| Recruiting | Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Un NCT05595954 | University Hospital, Basel, Switzerland | — |
| Completed | Cognitive Trajectories After Surgery, a Clinical, Observational Feasibility Study NCT05564195 | Karolinska Institutet | — |
| Active Not Recruiting | Biomarkers Associated With Postoperative Cognitive Dysfunction NCT05464355 | University of Oxford | — |
| Unknown | TEAS on Sleep Quality and POCD in Elderly Patients NCT04850196 | Shengjing Hospital | N/A |
| Unknown | Neuroimaging Combining Biomarkers for Identifying Long-term Cognitive Dysfunction and Delirium NCT05594966 | RenJi Hospital | — |
| Unknown | Effects of Perioperative Transauricular Vagus Nerve Electrical Stimulation on POD, POCD and CPSP NCT05439707 | Xuzhou Central Hospital | N/A |
| Unknown | Effects of General Anesthesia on Brain FC and Cognition in Children With Potential Neurological Damage NCT05602311 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Completed | Feasibility and Acceptability of Home-based Computerised Cognitive Training After Cardiac Surgery NCT05298540 | Barts & The London NHS Trust | N/A |
| Withdrawn | Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD NCT05398757 | Osijek University Hospital | N/A |
| Completed | Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients NCT05364216 | The First Hospital of Qinhuangdao | N/A |
| Completed | Five Years Follow-up of Neurological Outcome After Minimally Invasive Cardiac Surgery NCT05330260 | Jessa Hospital | — |
| Completed | The Effect of Optic Nerve Diameter on Postoperative Cognitive Function in Laparoscopic Hysterectomy NCT05286697 | Marmara University | N/A |
| Unknown | Total Intravenous Anesthesia Versus Sevoflurane Anesthesia for Endovascular Thrombectomy in Acute Ischemic Str NCT05493813 | Taipei Veterans General Hospital, Taiwan | N/A |
| Unknown | Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthr NCT05132595 | Tianjin Medical University General Hospital | N/A |
| Completed | Greek Validation of ACE III Test in Perioperative Patients NCT04312516 | Aristotle University Of Thessaloniki | — |
| Unknown | Chronic Postsurgical Pain, Postoperative Cognitive Dysfunction and Resilience NCT05614271 | McMaster University | — |
| Completed | Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery NCT02549560 | University of Sao Paulo | N/A |
| Unknown | Influence of Postoperative Cognitive Function in Patients With Sevoflurane Postconditioning on Carotid Intima NCT04950205 | Second Affiliated Hospital, School of Medicine, Zhejiang University | EARLY_Phase 1 |
| Unknown | The Effect of Desflurane on Postopertative Cognitive Dysfunction NCT04541823 | Beijing Chao Yang Hospital | Phase 4 |
| Completed | Effects of Thoracic Paravertebral Block Combined With S-ketamine on Postoperative Pain and Cognitive Function NCT05341375 | The First Hospital of Qinhuangdao | N/A |
| Active Not Recruiting | WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane NCT04765488 | I.M. Sechenov First Moscow State Medical University | N/A |
| Completed | Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and NCT04761458 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Completed | Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery NCT04679259 | SMG-SNU Boramae Medical Center | N/A |
| Completed | ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DIS NCT05483647 | Lviv National Medical University | N/A |
| Unknown | Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Sp NCT04697498 | Lviv National Medical University | N/A |
| Unknown | S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture NCT04643132 | Tianjin Medical University General Hospital | N/A |
| Completed | The Effect of Ketamine on Postoperative Cognitive Dysfunction. NCT04321746 | Assiut University | Phase 4 |
| Completed | The Effect of Obesity on the Incidence of Postoperative Cognitive Dysfunction in Gynecological Day Case Surger NCT04438915 | Beni-Suef University | N/A |
| Unknown | A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surger NCT04195204 | Beijing Chao Yang Hospital | Phase 4 |
| Completed | Correlation of Preoperative Anxiety With Early Postoperative Cognitive Dysfunction in Breast Cancer Patients NCT04701801 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | — |
| Recruiting | Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical P NCT04493996 | Heart and Brain Research Group, Germany | N/A |
| Completed | Normative Data for the Qmci-TW in a Taiwanese Sample NCT04598178 | National Taiwan University Hospital | — |
| Completed | Blood Brain Barrier Dysfunction and Postoperative Neurocognitive Disorders NCT04566562 | University of California, Los Angeles | — |
| Unknown | The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under Gene NCT04518839 | University of Zagreb | — |
| Unknown | Relationship Between Sleep EEG, Intraoperative EEG and Postoperative Cognitive Dysfunction NCT04481347 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Bilateral Bispectral Index, Asymmetries and Post-operative Delirium NCT06761573 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | Optic Nerve Sheath Diameter and Postoperative Cognitive Disfunction at Laparoscopic Surgery NCT07264764 | Duzce University | — |
| Completed | Transcutaneous Electrical Acupoint Stimulation for Postoperative Cognitive Dysfunction NCT04606888 | Subei People's Hospital of Jiangsu Province | N/A |
| Unknown | Perioperative Cognitive Trajectories in Deferred Surgery (CoTELE-SURGE) NCT04787536 | McMaster University | — |
| Unknown | Postoperative Cognitive Function and EEG NCT04219033 | Air Force Military Medical University, China | — |
| Unknown | Postoperative Cognitive Dysfunction in Elderly Urologic Oncology Patients (POCD) NCT04837391 | Istanbul University | — |
| Unknown | EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL NCT04279132 | Erzincan University | — |
| Completed | Taking Brain Monitoring to the Next Level NCT04246320 | University of California, Los Angeles | N/A |
| Completed | Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction NCT04189861 | Dartmouth-Hitchcock Medical Center | — |
| Unknown | Effect Of Aspirin Preoperative on Postoperative Cognitive Dysfunction In Elderly Patients Undergoing Knee Arth NCT04225702 | Xuzhou Medical University | — |
| Completed | Postoperative Cognitive Dysfunction in Heart Surgery NCT05406843 | Kocaeli University | — |
| Unknown | Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary By NCT04151914 | European Georges Pompidou Hospital | — |
| Completed | Different Frailty Scores to Incidence of Post-operative Delirium and Cognitive Dysfunction NCT04056871 | University of Malaya | — |
| Completed | Neurocognitive Function After Carotid Thrombendarterectomy NCT05739357 | Clinical Hospital Centre Zagreb | N/A |
| Completed | Endothelial Injury Mechanism in Elderly Patients Undergoing Major Surgery NCT03639896 | The First Affiliated Hospital of Anhui Medical University | Phase 4 |
| Completed | Neurological Effects of Goal-directed Fluid Therapy in Beach Chair Position Shoulder Surgery NCT03963063 | National Taiwan University Hospital | N/A |
| Unknown | Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive F NCT03988010 | TC Erciyes University | Phase 4 |
| Unknown | Effects of Amantadine on Postoperative Cognitive Dysfunction NCT03527134 | Zhiyi Zuo | N/A |
| Completed | Cognitive Outcome After Surgical and Transcatheter Aortic Valve Replacement NCT04535076 | Heart and Brain Research Group, Germany | N/A |
| Completed | Neuroinflammation in Cognitive Decline Post-cardiac Surgery NCT04520802 | Radboud University Medical Center | — |
| Completed | Intraoperative Infusion of Methylene Blue for Prevention of Postoperative Delirium and Cognitive Dysfunction i NCT04341844 | Fudan University | N/A |
| Unknown | Correlation Between Urine UACR and Postoperative Neurocognitive Disorder in Elderly Patients With Non-cardiac NCT03860714 | Han Yuan | — |
| Unknown | MD2, Cystatin C and DNA Methylation Tags as Serum Biomarkers for POCD. NCT03610191 | Xijing Hospital | — |
| Completed | Implementation of a Cognitive Training Program to Reduce the Risk of Postoperative Cognitive Dysfunction NCT03620968 | Centro Medico Teknon | N/A |
| Unknown | Risk Factor of POD and POCD After Cardiac Surgery NCT03635229 | Mahidol University | — |
| Unknown | the Research of the Cerebral Protection Effects of Electroencephalogram (SedLine) During Carotid Endarterectom NCT03622515 | Beijing Municipal Administration of Hospitals | N/A |
| Active Not Recruiting | Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery NCT03480061 | Sunnybrook Health Sciences Centre | Phase 4 |
| Unknown | Identification of Factors Causing Postoperative Cognitive Dysfunction in Patients Undergoing Cardiac Surgery W NCT03641833 | Rasa Bukauskiene | — |
| Completed | Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction NCT03802396 | Miles Berger, MD PhD | Phase 2 |
| Unknown | Tau/P-Tau and Neurocognitive Outcomes in Children NCT03511729 | Massachusetts General Hospital | — |
| Recruiting | Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperat NCT03360838 | University Hospital, Basel, Switzerland | — |
| Terminated | Risk Factors for Complications After Carotid Endarterectomy NCT03788980 | Ohio State University | — |
| Completed | Prognostic Factors Associated With Postoperative Cognitive Dysfunction After Surgery NCT03443440 | Milton S. Hershey Medical Center | — |
| Completed | Liver Transplant Does it Affect the Brain NCT04368052 | Ege University | N/A |
| Completed | Association Between Changes of GFAP After Surgery and Postoperative Delayed Cognitive Recovery NCT03683537 | Moscow Clinical Scientific Center | — |
| Unknown | Preoperative Pain and POCD in Elderly Patients NCT03393676 | RenJi Hospital | — |
| Unknown | Feasibility Study of Preoperative Cognitive Training in Cardiac Surgical Patients NCT02053207 | Papworth Hospital NHS Foundation Trust | N/A |
| Recruiting | Trajectory of Neuroinflammatory Markers in Cerebrospinal Fluid Prior to and After Thoracic Aortic Surgery NCT04523909 | Radboud University Medical Center | — |
| Completed | Longitudinal Cohort Study - for the Treatment of Acute Postoperative Pain and Postoperative Delirium, Postoper NCT03133858 | Charite University, Berlin, Germany | — |
| Terminated | Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients NCT03337282 | Ciusss de L'Est de l'Île de Montréal | — |
| Terminated | Prehabilitation Exercise Plus Perioperative Optimization of Senior Health NCT03291795 | Duke University | N/A |
| Completed | To Study the Effect of Sevoflurane and Propofol V Sevoflurane and Dexmedetomidine on Postoperative Cognitive D NCT03145714 | Rajiv Gandhi Cancer Institute & Research Center, India | N/A |
| Active Not Recruiting | Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2) NCT03147937 | Dr. Stephen Choi | — |
| Completed | POCD: Correlations With the Gene Polymorphism and the Concentrations of Plasma Homocysteine, Folic Acid and Vi NCT03084393 | Xuzhou Medical University | — |
| Completed | Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce NCT03074604 | Collegium Medicum w Bydgoszczy | N/A |
| Completed | S100B Protein and Postoperative Cognitive Dysfunction NCT03018522 | Antalya Training and Research Hospital | — |
| Completed | fMRI Connectivity in Fracture Hip Patients NCT02997930 | University of Florida | N/A |
| Completed | Assessment of POCD After Steep Trendelenburg Position and CO2 Pneumoperitoneum With Cerebral Oxygen NCT03372135 | RenJi Hospital | — |
| Unknown | The Assessment of POCD After TURBT Under Spinal Anesthesia NCT03029676 | Medical University of Warsaw | Phase 4 |
| Completed | Neurological Outcome After Minimal Invasive Coronary Artery Bypass Graft NCT02979782 | Jessa Hospital | — |
| Completed | Postoperative Cognitive Dysfunction: Correlations With Olfactory Dysfunction and Related Gene Changes NCT02992600 | Han Yuan | — |
| Completed | Prevention of Early Postoperative Decline NCT02908464 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Whether Dexmedetomidine Can Improve the Prognosis of Elderly Patients With Postoperative Cognitive Dysfunction NCT02923128 | Zhejiang Cancer Hospital | Phase 4 |
| Completed | Comparison of Postoperative Outcome After Sevoflurane and Propofol Anaesthesia NCT02931877 | Xinqiao Hospital of Chongqing | Phase 4 |
| Unknown | Comparison of Desflurane With Sevoflurane for School-age Children in Postoperative Cognitive Function NCT02909413 | Shengjing Hospital | N/A |
| Unknown | Correlations of Epigenetic Changes With POCD in Surgical Patients NCT02965235 | Central South University | — |
| Unknown | Correlation Between Postoperative Cognitive Dysfunction and Telomere Length in Patients With Non-cardiac Surge NCT03703973 | Xuzhou Medical University | — |
| Completed | The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Su NCT02848599 | Osijek University Hospital | Phase 2 |
| Completed | Cognitive Changes After Major Joint Replacement NCT02964221 | Dr. Stephen Choi | — |
| Completed | Early Postoperative Cognitive Dysfunction After Closed Loop Anesthesia vs Inhalational Anesthesia or TIVA NCT02656901 | University of Foggia | N/A |
| Completed | Optimizing Postoperative Cognition the Elderly NCT02650687 | Icahn School of Medicine at Mount Sinai | — |
| Completed | Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfun NCT02045004 | Nicolai Goettel | — |
| Completed | Trajectory of Recovery in the Elderly NCT02275026 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Impact of Anesthesia Maintenance Methods on Incidence of Postoperative Delirium NCT02662257 | Peking University First Hospital | N/A |
| Completed | Effect of Sedation on Cognitive Performance in the Elderly NCT03089866 | University of Alabama at Birmingham | — |
| Unknown | Cognitive Dysfunction Following Cardiac Surgery NCT02767713 | Clinical Hospital Center, Split | Phase 4 |
| Completed | The Effects of Anaesthesia on Cerebral Oxygenation and Cognitive Function in Carotid Endarterectomy NCT02771418 | Northern State Medical University | N/A |
| Completed | Ulinastatin Improves Post-Cardiac Surgery Cognitive Dysfunction NCT06268249 | Qin Zhang | — |
| Unknown | The Effect on Cerebral Oxygenation of Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit in C NCT02108093 | Amphia Hospital | N/A |
| Unknown | Effects of Different Doses of Dexmedetomidine on Postoperative Cognitive Dysfunction in Elderly Hypertensive P NCT02224443 | First Affiliated Hospital Xi'an Jiaotong University | Phase 4 |
| Completed | Perfusion Pressure Cerebral Infarction Trial (PPCI) NCT02185885 | Rigshospitalet, Denmark | N/A |
| Completed | Risk Factors for Early POCD in the Patients With PSM Undergoing CRS-HIPEC NCT02462564 | Wuhan University | — |
| Completed | Study of Prevention of Postoperative Delirum to Reduce Incidence of Postoperative Cognitive Dysfunction NCT03060174 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Study of Depressive Symptoms Predicting Postoperative Cognitive Dysfunction NCT02210312 | Universitätsklinikum Hamburg-Eppendorf | — |
| Terminated | Dexamethasone and Postoperative Delirium NCT02109081 | Endeavor Health | Phase 4 |
| Unknown | Postoperative Cognitive Dysfunction in Elderly NCT02068742 | Università degli Studi dell'Insubria | N/A |
| Completed | Depth of Anaesthesia and Postoperative Cognitive Decline in Patients Undergoing Heart Surgery NCT01743456 | King's College Hospital NHS Trust | N/A |
| Unknown | Post Cardiac Surgery Neurocognitive Decline: Correlations Between Neuropsychological Tests and Functional MRI NCT01622452 | Fondazione Toscana Gabriele Monasterio | — |
| Unknown | Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty NCT01934049 | Chinese PLA General Hospital | Phase 4 |
| Completed | Reconstructing Consciousness and Cognition NCT01911195 | University of Michigan | N/A |
| Completed | Ketamine and Changes of the Short Portable Mental Status Questionnaire NCT02049411 | Instituto Mexicano del Seguro Social | Phase 2 |
| Unknown | Exploration of Neuroimaging and Biochemical Prognostic Indicators for POCD NCT02164669 | wangqiang | — |
| Completed | The Difference in Cerebral Oxygenation Between Propofol and Sevoflurane NCT01757561 | First Affiliated Hospital, Sun Yat-Sen University | — |
| Completed | Optimization of Desflurane in Elderly Patients NCT01700907 | Sapporo Medical University | Phase 1 / Phase 2 |
| Active Not Recruiting | Effects of Brain Beta-Amyloid on Postoperative Cognition NCT01606488 | University of California, San Francisco | Phase 4 |
| Completed | Peri-Anesthetic Imaging of Cognitive Dysfunction NCT01322672 | Vanderbilt University | — |
| Unknown | Short-Term and Long-Term Cognitive Outcomes in Adults After Cardiac Surgery NCT05172362 | Research Institute for Complex Problems of Cardiovascular Diseases, Russia | — |
| Completed | Dexamethasone for the Prevention of Postoperative Cognitive Dysfunction NCT01332812 | University of Sao Paulo | Phase 4 |
| Completed | Cerebral Oximetry and Neurological Outcomes in Aortic Arch Surgery Patients NCT01149148 | University of Michigan | Phase 3 |
| Completed | Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up NCT01103752 | Lene Krenk | — |
| Terminated | Role of Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Sur NCT00991328 | Icahn School of Medicine at Mount Sinai | Phase 3 |
| Completed | Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients NCT00917124 | University of Zagreb | N/A |
| Unknown | Correlation Between Markers of Neuronal Injury and Cognitive Dysfunction After Coronary Artery Bypass Surgery NCT01550159 | Maria José Carvalho Carmona | — |
| Recruiting | Retrospective Evaluation of POCD Data of Studies From KAI, Charité - Universitätsmedizin Berlin NCT02832193 | Charite University, Berlin, Germany | — |
| Completed | Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial NCT00835159 | NYU Langone Health | Phase 4 |
| Completed | Postoperative Cognitive Decline, Inflammation, and Plasma Levels of Beta-amyloids NCT00850928 | NYU Langone Health | — |
| Terminated | n-3 Enriched Nutrition Therapy and Postoperative Cognitive Dysfunction After Cardiac Surgery NCT00757913 | University Hospital, Basel, Switzerland | Phase 4 |
| Completed | Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve NCT00561678 | Icahn School of Medicine at Mount Sinai | Phase 4 |
| Completed | Modafinil to Prevent Postoperative Cognitive Decline NCT03914118 | The Cooper Health System | Phase 2 |
| Completed | Whole Genome Single Nucleotide Polymorphisms in Elderly Patients With Postoperative Cognitive Dysfunction NCT02864173 | University Hospital, Basel, Switzerland | — |
| Terminated | Cognitive Protection - Dexmedetomidine and Cognitive Reserve NCT00455143 | Icahn School of Medicine at Mount Sinai | Phase 4 |
| Completed | Does APOE-e4 Predict Delirium and Cognitive Dysfunction After Surgery? NCT00911677 | Ottawa Hospital Research Institute | — |