NCT01757561

The Difference in Cerebral Oxygenation Between Propofol and Sevoflurane

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 144 (actual)
• Sponsor: First Affiliated Hospital, Sun Yat-Sen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

the purpose of this study is to investigate whether propofol and sevoflurane have difference effect on cerebral oxygenation .

Detailed description

the purpose of this study:(1) to investigate the incidence of preoperative cerebral oxygenation abnormity (SjvO2 \<55%) and its relationship with intraoperative cerebral desaturation and POCD. (2) To investigate the change of intraoperative cerebral oxygen supply and demand balance and the incidence of cerebral desaturation in patients with abnormal preoperative cerebral oxygenation during sevoflurane anesthesia. (3)To investigate the incidence of early POCD in patients with abnormal preoperative cerebral oxygenation during sevoflurane and propofol anesthesia.

Conditions

• Cerebral Hypoxia
• Postoperative Cognitive Dysfunction

Interventions

Type	Name	Description
PROCEDURE	propofol	use total intravenous anesthesia with propofol
PROCEDURE	sevoflurane	use inhalation anesthesia with sevoflurane

Timeline

• Start date: 2012-12-01
• Primary completion: 2013-12-01
• Completion: 2014-03-01
• First posted: 2012-12-31
• Last updated: 2015-09-18
• Results posted: 2015-09-18

Locations

1 site across 1 country: China