NCT03963063

Neurological Effects of Goal-directed Fluid Therapy in Beach Chair Position Shoulder Surgery

Efficacy of Perioperative Goal-directed Fluid Therapy in Preventing Cerebral Desaturation and Postoperative Cognitive Dysfunction After Beach Chair Position Shoulder Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Patients receiving beach chair position shoulder surgery are vulnerable to perioperative cerebral desaturation, which is reported to be a risk factor for postoperative cognitive dysfunction. Investigators design this study to test the efficacy of perioperative goal-directed therapy in preventing cerebral desaturation and postoperative cognitive dysfunction in patients receiving beach chair position shoulder surgery.

Conditions

• Postoperative Cognitive Dysfunction
• Anesthesia

Interventions

Type	Name	Description
PROCEDURE	Goal-directed fluid therapy	Patients in the group will follow our mini-fluid challenge test goal-directed therapy protocol, maintaining: * individualized optimised stroke volume by mini-fluid challenge first * keep mean arterial pressure ≧65 mmHg * keep systolic blood pressure ≦140 mmHg * keep cardiac index ≧ 2.5 L/min/cm2
PROCEDURE	Non goal-directed fluid therapy	Patients in the group will receive standard perioperative care at the discretion of care-giving anesthesiologist, maintaining: * keep mean arterial pressure ≧65 mmHg * keep systolic blood pressure ≦140 mmHg

Timeline

• Start date: 2019-06-27
• Primary completion: 2021-03-31
• Completion: 2021-03-31
• First posted: 2019-05-24
• Last updated: 2022-01-21

Locations

1 site across 1 country: Taiwan