Trials / Unknown
UnknownNCT01934049
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
The Effect of Dexmedetomidine on Postoperative Recovery in Elderly Patients With Femoral Neck Fracture Undergoing Hip Hemi-arthroplasty
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- Sponsor
- Chinese PLA General Hospital · Academic / Other
- Sex
- All
- Age
- 75 Years
- Healthy volunteers
- Not accepted
Summary
Hip fractures incidence grows rapidly with the aging of the population. After indicated surgical treatment, hip fracture patients experience high rates of postoperative complications, postoperative delirium (PD), postoperative cognitive dysfunction (POCD), leading to poor postoperative recovery during hospitalization, which can cause disability, distress for both patients and their families, are associated with other medical complications and account for significant additional health care costs. We currently use dexmedetomidine in elderly patients with hip fractures undergoing hip hemi-arthroplasty in order to improve postoperative recovery and prevent and treating PD and POCD. Dexmedetomidine is a drug used for sedation in critically ill patients that provides some pain relief and controls the bodies response to stress. The sedation produced by dexmedetomidine appears more similar to natural sleep than any other drug used for anesthesia and postoperative sedation. Data suggesting that dexmedetomidine can prevent delirium following cardiac surgery and the developing understanding of the causes of PD and POCD suggest that dexmedetomidine will be particularly effective.
Conditions
- Femoral Neck Fractures
- Postoperative Complications
- Inflammatory Response
- Postoperative Delirium
- Postoperative Cognitive Dysfunction
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | hip arthroplasty | Every patient with femoral neck fractures must undergo hip hemi-arthroplasty. |
| DRUG | Total Intravenous Anesthesia and Peripheral nerve blocks | Every patient receives Peripheral nerve blocks and Total Intravenous Anesthesia with propofol |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2014-02-01
- Completion
- 2014-06-01
- First posted
- 2013-09-04
- Last updated
- 2013-09-10
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT01934049. Inclusion in this directory is not an endorsement.