Trials / Completed
CompletedNCT04679259
Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery
Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery After Cardiac Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 82 (actual)
- Sponsor
- SMG-SNU Boramae Medical Center · Academic / Other
- Sex
- All
- Age
- 55 Years
- Healthy volunteers
- Not accepted
Summary
Delayed neurocognitive recovery is defined as a cognitive decline arising after surgery. In the present study, the authors evaluate the level of D-Amino Acid Oxidase, D-serine and Serine racemase in blood as an indicator of delayed neurocognitive recovery after cardiac surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Blood sampling for assessment of the level of D-Amino Acid Oxidase, D-serine and Serine in blood | Blood sampling is done before surgery and at 1, 2, and 7 day after surgery. The level of D-Amino Acid Oxidase, D-serine and Serine in blood are assessed. |
| DIAGNOSTIC_TEST | Neurocognitive test | Neurocognitive test is performed before surgery and at 7 day after surgery |
| DIAGNOSTIC_TEST | Assessment of delirium | Postoperative delirium is assessed daily during 7 days after surgery. |
Timeline
- Start date
- 2021-01-06
- Primary completion
- 2025-10-22
- Completion
- 2025-10-29
- First posted
- 2020-12-22
- Last updated
- 2026-01-20
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT04679259. Inclusion in this directory is not an endorsement.