NCT03988010

Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 54 (estimated)
• Sponsor: TC Erciyes University · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

Evaluation of the effect of preoperative intravenous administration of amantadine sulfate on the prevention of the development of early cognitive dysfunction in elderly patients undergoing laparoscopic radical prostatectomy

Detailed description

Investigators believe that the preoperative prophylactic amantadine sulphate will reduce the incidence of postoperative cognitive disfunction (POCD) in patients with laparoscopic radical prostatectomy due to the neuroprotective effect, alertness enhancing effect and neuron protective effects.

Conditions

• Postoperative Cognitive Dysfunction

Interventions

Type	Name	Description
DRUG	Amantadine Sulfate	200mg/500ml i.v. solution for infusion
DRUG	Placebo (for amantadine sulphate)	500 cc 0.9% sodium chloride

Timeline

• Start date: 2019-05-01
• Primary completion: 2019-12-01
• Completion: 2019-12-01
• First posted: 2019-06-17
• Last updated: 2019-06-20

Locations

1 site across 1 country: Turkey (Türkiye)