Pain, Acute

391 registered clinical trials studyying Pain, Acute — 46 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Phase 1 Study of SBS-147 in Healthy Adults NCT07335913	Sparian Biosciences, Inc	Phase 1
Not Yet Recruiting	Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients NCT07144033	Chinese University of Hong Kong	N/A
Not Yet Recruiting	Three Brief Psychological Interventions for Acute Pain in Inpatients in Boyacá NCT07254923	Universidad Pedagógica y Tecnológica de Colombia	N/A
Recruiting	A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultra NCT07249827	McGill University Health Centre/Research Institute of the McGill University Health Centre	Phase 2
Recruiting	Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain NCT07053774	Wake Forest University Health Sciences	Phase 2
Completed	External Oblique Intercostal Block in Laparoscopic Cholecystectomy NCT07164664	Ondokuz Mayıs University	N/A
Recruiting	Effect of Vitamin C on Pain Reduction After an Emergency Department Visit NCT06306183	Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal	N/A
Recruiting	Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain NCT07024199	Medical University of Warsaw	Phase 4
Completed	Impact of Vitamin C on Pain Detection and Tolerance Threshold NCT06971315	Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal	N/A
Recruiting	Impact of Virtual Reality in Cardiac Electrophysiology NCT07009951	University of Calabria	—
Recruiting	Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements NCT06960317	University of California, San Diego	N/A
Not Yet Recruiting	Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement NCT06974019	University of California, San Diego	N/A
Not Yet Recruiting	Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement NCT06974032	University of California, San Diego	N/A
Recruiting	CORA-Q15: Continuous vs. Single-injection Interscalene Block on QoR-15 in Outpatient Rotator Cuff Surgery NCT06754657	Pontificia Universidad Catolica de Chile	Phase 4
Recruiting	Perioperative Intravenous Nimodipine Trial NCT07048522	University of Ioannina	N/A
Recruiting	Distraction as Treatment for Pain in Children in Resource-scarce Settings NCT06933303	Vrinnevi Hospital	N/A
Completed	Magic Bowl Virtual Reality Analgesia NCT07192822	University of Washington	N/A
Completed	Effects of Hand Massage Applied With Two Different Methods NCT06853860	Kutahya Health Sciences University	N/A
Recruiting	Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume NCT07411417	Özgül Aydemir	N/A
Recruiting	Variability in Analgesic Response to Ibuprofen NCT06539741	University of Pennsylvania	—
Not Yet Recruiting	Use of Equity Report Cards to Mitigate Disparities in Emergency Medical Services (EMS) Care for Injured Childr NCT06531421	Children's National Research Institute	N/A
Recruiting	Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma NCT06626334	Rebecca E Kotcher, MD	N/A
Not Yet Recruiting	Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA) NCT06604507	Winfried Meißner	—
Not Yet Recruiting	Distraction As Multimodal Pain Management NCT06591195	Radboud University Medical Center	N/A
Not Yet Recruiting	Effect of Pranic Healing on Cardiorespiratory Indices and Pain During Venipuncture in Children NCT06571357	Near East University, Turkey	N/A
Recruiting	Affecting Factors for Chronic Pain After Mastectomy NCT06592053	Ankara Etlik City Hospital	—
Enrolling By Invitation	Relieving Pain and Improving Sleep: Evaluating Topical Pain Relief and Sleep Patches NCT06505005	SuperPatch Limited LLC	N/A
Recruiting	Affecting Factors for Chronic Pain After Sternotomy NCT06534372	Ankara Etlik City Hospital	—
Completed	Effect of Different Subcutaneous Injection Methods on Pain and Satisfaction NCT06829407	Trakya University	N/A
Completed	Effects of Acute Pain on Motor Learning in Young vs Older Adults NCT05471557	University of Delaware	N/A
Completed	The Effects of Acupressure and Paternal Holding on Pain and Physiological Parameters During Heel Lancing NCT06513897	Baskent University	N/A
Not Yet Recruiting	Prehospital Analgesia in Adults Using Inhaled Methoxyflurane Study NCT06392087	Ottawa Hospital Research Institute	Phase 4
Completed	Music for Pain in the Waiting Room NCT06511843	Florida State University	N/A
Completed	The Effect of Mechanical Vibration and Helfer Skin Tap Technique on Procedural Pain in Infants During Vaccinat NCT06454812	Istanbul Medeniyet University	N/A
Completed	The Effect of Neurolingualistik Programming (NLP) on Pain Score, Fear of Pain and Pain Catastrophizing Before NCT06493266	Sanliurfa Education and Research Hospital	N/A
Completed	The Effect of NLP on Pain Before Uterine Curettage Due to the Fetal Demise NCT06493305	Sanliurfa Education and Research Hospital	N/A
Recruiting	Safety and Efficacy of Sufentanil Administration by Paramedics in Acute Trauma NCT06514469	Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.	—
Completed	Ultrasound Guided Serratus Anterior Plane Block in ED Patients With Rib Fractures NCT06299137	Rhode Island Hospital	EARLY_Phase 1
Recruiting	TENS Analgesia During Outpatient Urethral Bulking for Stress Urinary Incontinence. NCT06369922	University of Rochester	N/A
Completed	The Effect of Facilitated-tucking and ShotBlocker on Pain Caused by Vaccination in Healthy Infants NCT06377748	Istanbul Medeniyet University	N/A
Recruiting	The Efficacy of Acu-TENS as an Adjunct Analgesic During USG-MVA NCT06411054	Chinese University of Hong Kong	N/A
Completed	Open-Label Placebo for Non-Specific Pain in the ED NCT06408519	Bruno Minotti	N/A
Terminated	Ketamine-assisted Therapy for Advanced GI Cancer NCT06077487	Brian Anderson, MD	Phase 4
Withdrawn	Mind-body Therapies for Injury-related Pain Management in Elite Athletes NCT06095687	The University of Queensland	N/A
Recruiting	Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED NCT06364540	Antonios Likourezos	Phase 4
Recruiting	TENS Unit for Analgesia During IUD Insertion NCT06240260	Tufts Medical Center	N/A
Recruiting	The Effect of Heart Sound and White Noise on Pain and Physiological Parameters During Hepatitis B Vaccine Inje NCT06279169	Bartın Unıversity	N/A
Recruiting	Methadone Pharmacokinetics in End-stage Renal Disease NCT06056245	Pontificia Universidad Catolica de Chile	—
Completed	Effect of Cold Application and Vibration in Reducing Pain During Vaccination in Children NCT06566378	Burdur Mehmet Akif Ersoy University	N/A
Recruiting	Stellate Ganglion Block for Prevention of Post Mastectomy Depression NCT06263907	Mansoura University	N/A
Completed	Transauricular Vagal Nerve Stimulation, Pressure Pain and Interoception NCT06240026	Aalborg University	N/A
Completed	Surgical Intervention in Deep Sedation: No Pain or no Memory NCT06963749	ASL Novara	—
Completed	Duration of Music Interventions and Pain Tolerance (DOMINANT) NCT06286137	Erasmus Medical Center	N/A
Completed	The Effect of Kinesio Taping in Pediatric Surgery NCT06344897	KTO Karatay University	N/A
Recruiting	Lumbar ESPB in Hip Replacement Surgery NCT06282666	Medical University of Lublin	N/A
Completed	Comparison Three Methods on Endotracheal Aspiration in Preterm Infants NCT05434364	Istanbul University - Cerrahpasa	N/A
Completed	The PainSMART Research Program: Evaluating a Pain Education Strategy for Patients Seeking Primary Care Physiot NCT06187428	Kajsa Johansson	N/A
Completed	Online Psychology Program for Chronic Pain After Surgery NCT06455345	University Health Network, Toronto	N/A
Completed	SPSIPB for Breast Cancer Surgery NCT06225908	Zonguldak Bulent Ecevit University	N/A
Active Not Recruiting	Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients NCT05913284	Chinese University of Hong Kong	Phase 3
Completed	The Effects of Body Mass Index on Erector Spinae Plane Block Analgesia NCT06257953	Atatürk Chest Diseases and Chest Surgery Training and Research Hospital	—
Completed	Pre-post Erector Spine Plane Block-spinal Surgery NCT06215053	Aydin Adnan Menderes University	N/A
Unknown	Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis NCT04614610	Community Medical Center, Toms River, NJ	Phase 2
Completed	TAP Block With Methyl-prednisolone as a Pain Treatment Modality After Total Abdominal Hysterectomy Procedures NCT06131593	Kasr El Aini Hospital	N/A
Active Not Recruiting	Efficacy of Manuel Pressure and Local Cold Spray in Reducing Injection Pain in Pregnant Women NCT06231719	Gulsum Coskun	N/A
Unknown	Virtual Reality Therapy for Pain Management at the Emergency Department NCT06089642	Radboud University Medical Center	N/A
Completed	Prevalence of Pain in Hospitalized Cirrhotic Patients NCT06062108	Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer	—
Recruiting	Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity NCT06411197	Kristian Kjær Petersen	N/A
Recruiting	Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain NCT05555576	Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal	N/A
Recruiting	Valacyclovir in Pain Management of Acute Apical Abscesses NCT05266040	University of California, San Francisco	Phase 2
Recruiting	UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture NCT05865327	Sunnybrook Health Sciences Centre	N/A
Completed	Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers NCT06005480	Brigham and Women's Hospital	Phase 1
Completed	Effect of Mother's Touch and Nurse's Therapeutic Touch on Pain Level and Crying Time During Heel Blood Collect NCT06350084	Burdur Mehmet Akif Ersoy University	N/A
Completed	Ultrasound-Guided Serratus and Transversus Thoracic Muscle Plane Block Vs. Erector Spinae Plane Block for Acut NCT06625580	Ataturk University	N/A
Completed	Use of Dexamethasone Via Two Different Methods in PENG Block NCT06242028	Ondokuz Mayıs University	—
Recruiting	Latinx Children and Surgery NCT06020677	University of California, Irvine	N/A
Completed	Use of the Equimolar Mixture of Oxide Nitrous and Oxygen (EMONO) Associated With Audiovisuals in Children NCT05435118	Azienda Socio Sanitaria Territoriale di Lodi	N/A
Terminated	Atmospheric Projection in the Emergency Department NCT05967988	University of Lausanne Hospitals	N/A
Completed	Parecoxib in Total Knee Arthroplasty NCT05924412	University of Chile	Phase 4
Completed	The Effects of Finger Puppet, Abeslang Puzzle, and Pinwheel on Pain and Anxiety During Blood Sampling Procedur NCT05904483	Bartın Unıversity	N/A
Completed	Effect of Kangaroo Care and Swaddling Methods on Pain Level and Crying Time During Heel Blood Collection NCT06350071	Burdur Mehmet Akif Ersoy University	N/A
Completed	Periprostatic Nerve Block vs. Intravenous Ibuprofen for Pain Management During Transrectal Prostate Biopsy NCT06737939	University of Gaziantep	N/A
Completed	Virtual Reality Distraction During Phlebotomy in Children NCT06336811	Dokuz Eylul University	N/A
Unknown	Comparison of Blood Glucose Measurement Values NCT05848362	Uludag University	N/A
Completed	The Effect of Therapeutic Play on Pain, Fear, Anxiety and Physiological Parameters and Parents' Satisfaction NCT06415188	Selcuk University	N/A
Unknown	The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain NCT05759364	Western Galilee Hospital-Nahariya	N/A
Completed	Sensory Assessment and Regression Rate of Bilateral External Oblique Intercostal Block and m-TAPA Block NCT05744544	Samsun University	—
Completed	Bupivacaine Versus Bupivacaine Plus Lidocaine in Infraclavicular Block NCT05834023	Hospital de San Carlos Dr. Benicio Arzola Medina	Phase 4
Unknown	Neonatal Pain Management and Pain Monitoring Using New Methods NCT04967118	University of Oulu	N/A
Completed	Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circ NCT06086106	Salmaniya Medical Complex	—
Completed	Testing Different Methods of Intramuscular Injection NCT05577832	Muş Alparslan University	N/A
Completed	Peripheral Central Catheter (PICC) Care NCT06352918	Ataturk University	N/A
Unknown	The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture NCT05857462	Mahidol University	N/A
Unknown	Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surger NCT05843344	Dr Kassiani Theodoraki	N/A
Unknown	Postoperative Pain Management on Uvulopalatopharyngoplasty Patients NCT05825495	Li-Jen Hsin	Phase 4
Completed	The Effectiveness of the Therapeutic Toys During Intravenous Canula Insertion NCT05839184	Izmir Katip Celebi University	N/A
Completed	Safety of Ibuprofen After Major Orthopaedic Surgeries NCT05575700	Naestved Hospital	Phase 4
Completed	Effects of Acute Pain vs Context Change on Motor Learning Retention in Young Adults NCT05626582	University of Delaware	N/A
Unknown	Evaluation of the Effect of a Food Supplement Based on Hydrolyzed Collagen on Joint Function. NCT05917925	Francisco Javier Martínez Noguera	N/A
Completed	Preanesthetic Analgesia/Nociception Index (ANI) and Propofol Injection Pain NCT05049577	Wonkwang University Hospital	N/A
Completed	Effects of Acute Pain on Cognitive Performance in Young Adults NCT05625776	University of Delaware	N/A
Completed	The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery NCT05498025	Geisinger Clinic	N/A
Completed	Topical Anaesthesia in Cutaneous Head and Neck Surgery NCT06274905	University Hospital Waterford	N/A
Completed	Opioid Use and Predicting Factors at the Emergency Department NCT06072950	Radboud University Medical Center	—
Completed	Effect of Stress Ball in Angiography NCT06131606	Firat University	N/A
Unknown	The Effect of Puppet Show on Pain and Fear During Subcutaneous Injection in Children With Leukemia NCT06013501	Dokuz Eylul University	N/A
Completed	The Effect of VR on Pain, Anxiety And Fear During Venipuncture in Children NCT06527092	Ege University	N/A
Unknown	'The Effect of Adding LFCN Block to PENG NCT06226675	Zonguldak Bulent Ecevit University	N/A
Completed	Assessment of Efficacy of Sacral Erector Spinae Plane Block for Postoperative Analgesia in Pediatric Rectal Bi NCT06362811	Istanbul University	N/A
Withdrawn	Impact of Virtual Reality Hypnosis on Pain and Anxiety During Dressings Change in Burn Patients NCT03924908	University of Liege	N/A
Unknown	Tolerance Assesment of the Usage of an Analgesic Dose of Esketamine for Treatment of Moderate to Intense Pain NCT05666869	Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences	—
Completed	Low Dose Ketamine Infusion for Analgesia in the Emergency Department to Reduce Side Effects NCT05518877	Summa Health System	Phase 4
Completed	Mid-point to Pleura Transverse Process Block Versus Thoracic Intervertebral Foramen Block NCT05348330	San Salvatore Hospital of L'Aquila	N/A
Active Not Recruiting	Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement NCT05283980	Beth Israel Deaconess Medical Center	Phase 2 / Phase 3
Unknown	Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery NCT04718116	Aretaieion University Hospital	N/A
Unknown	Opioid Sparing Anesthesia in Cervical Spine Surgery NCT05717361	Evangelismos Hospital	N/A
Completed	Distraction on Procedure-Related Emotional Appearance, Pain, Fear, and Anxiety During Phlebotomy in Children NCT05818761	Dokuz Eylul University	N/A
Unknown	Investigating Composite Biomarkers for Pain Catastrophizing NCT04787198	Aalborg University	N/A
Withdrawn	Pilot Trial: Comparing Buzzy to Intradermal Lidocaine for Peripheral IV Cannulation in Adults NCT04647084	Steward St. Elizabeth's Medical Center of Boston, Inc.	Phase 4
Unknown	Utility of CYP2D6 Genotyping to Improve the Efficacy and Safety of Tramadol NCT05657704	Fundación de Investigación Biomédica - Hospital Universitario de La Princesa	Phase 4
Completed	Intraoperative Clonidine for Postoperative Pain Management in Patients Undergoing Surgical Treatment for Endom NCT05560230	University of Aarhus	Phase 4
Unknown	Patient Augmented Reality and Vibratory Array Otorhinolaryngology Procedures NCT06227039	University of Virginia	N/A
Unknown	The Impact of Esmolol Administration on Postoperative Recovery NCT05567822	Aretaieion University Hospital	N/A
Withdrawn	VR Mindfulness Study NCT05592782	University of California, Los Angeles	N/A
Unknown	Developing a Virtual Reality (VR)-Based Prototype for Perioperative Care - a Proof of Concept Study NCT05564013	Changi General Hospital	N/A
Completed	Adaptation of the Motor System to Experimental Pain NCT05396820	Universite du Littoral Cote d'Opale	N/A
Completed	Racial Discrimination, Pain, and the Buffering Influences of Acknowledgment NCT06113926	George Washington University	N/A
Not Yet Recruiting	PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders NCT05468684	University of applied sciences	—
Completed	The Effect of "Quantum-Touch" on Pain, Fear, and Anxiety of the Children NCT05828264	Trakya University	N/A
Completed	Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function NCT05886608	Contrad Swiss SA	N/A
Unknown	Opioid Sparing Anesthesia in Lumbar Spine Surgery NCT05594407	Aretaieion University Hospital	N/A
Completed	Decoding Mechanisms of Pain Modulation NCT05336370	University of Oslo	N/A
Completed	Lornoxicam Versus Etodolac After Third Molar Surgery NCT05679453	Kutahya Health Sciences University	Phase 4
Completed	White Noise and Therapeutic Touch on Pain and Comfort Level in Newborns During Heel Lance NCT05524337	Dokuz Eylul University	N/A
Completed	The Adolescent Surgery Experience: A Mixed Methods Analysis NCT05482919	Children's Hospital of Philadelphia	—
Completed	Developing an Objective Measure of Experienced Pain NCT05415423	University of Zurich	N/A
Completed	ESP Block in VATS: Programmed Intermittent Bolus Versus Continuous Infusion on Quality of Recovery NCT05181371	Mater Misericordiae University Hospital	N/A
Unknown	A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surg NCT05598307	Aretaieion University Hospital	N/A
Unknown	Ultrasound Guided Nerve Block for Hip Fracture Pain Management at Emergency Department NCT05403073	Hospital San Carlos, Madrid	N/A
Completed	PENG Block With Two Diffirent Volume NCT05358587	Samsun University	N/A
Completed	Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries NCT05375916	University of Alberta	N/A
Completed	Pain in Newborn Heel Blood Collection NCT05510271	Ataturk University	N/A
Unknown	The Nociception Level (NOL) Index for Pain Assessment in the Adult Intensive Care Unit NCT05339737	McGill University	—
Completed	Peripheral Intravenous Central Catheter Intervention in Preterm Infants NCT05359809	Ataturk University	N/A
Completed	Veın Imagıng Devıce And Vırtual Realıty NCT06243419	Dokuz Eylul University	N/A
Completed	Quadratus Lumborum Block vs Erector Spinal Block for Post Abdomen Surgery Analgesia NCT05446727	Jagiellonian University	N/A
Completed	Virtual Reality Analgesia for Brief Thermal Pain NCT05130307	University of Washington	N/A
Completed	ShotBloker and Helfer Skin Tap Technique During Intramuscular Injection in Children NCT05563233	Tarsus University	N/A
Recruiting	The Effect of Two Different Cognitive-Behavioral Combined Programs in Blood Collection NCT05263297	Karamanoğlu Mehmetbey University	N/A
Completed	Optimal Timing of Parasternal Intercostal Nerve Block Application for Acute Pain Management in Cardiac Surgery NCT05363540	Benha University	N/A
Completed	Promoting Self-Management of Breast and Nipple Pain With Technology (PROMPT) for Breastfeeding Women Study NCT05262920	University of Connecticut	N/A
Completed	The Effect of Stress Ball and Breathing Exercises on Reducing Fear and Pain Associated with PCR Testing NCT05250544	Karamanoğlu Mehmetbey University	N/A
Unknown	Feasibility & Acceptability of a Patient-Oriented Music Intervention to Reduce Pain in the Intensive Care: A P NCT05320224	McGill University	N/A
Completed	Biofeedback Based Virtual Reality Intervention to Manage Postoperative Pain NCT04943874	Vanessa Olbrecht	N/A
Unknown	Opioid-free Anesthesia in Thyroidectomies NCT05243940	Aretaieion University Hospital	N/A
Completed	Virtual Reality on Pain, Fear, and Emotional Appearance During Phlebotomy in Pediatric Hematology and Oncology NCT05675358	Dokuz Eylul University	N/A
Completed	Spinal Analgesia as Fast Track Painless Labor NCT05271760	Prince Sattam Bin Abdulaziz University	—
Completed	Pain and Comfort Level During Orogastric Catheter Insertion in Preterms NCT06222047	Dokuz Eylul University	N/A
Unknown	Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techni NCT05233683	King Saud University	Phase 3
Unknown	Reducing Pain During Heel Blood Collection in Preterm Newborns NCT05431452	Suleyman Demirel University	N/A
Completed	The Effect of Helfer Skin Tap Technique on Pain, Fear, and Anxiety in Children Undergoing Intramuscular Inject NCT05250804	Aylin Kurt	N/A
Terminated	TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery NCT04393207	Yale University	Phase 4
Unknown	Influence of Intra-abdominal Ropivacaine 0.5% Spray on Postoperative Analgesia in Laparoscopic Surgery. NCT05173090	University of Liege	N/A
Unknown	TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection NCT05211791	South Egypt Cancer Institute	N/A
Unknown	Effect of Ultrasound Guided Thoracic Interfascial Plane Block Versus Erector Spinae Plane Block After Mastecto NCT05176938	Tanta University	N/A
Withdrawn	Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emerg NCT04061330	The University of Texas Health Science Center, Houston	Phase 2
Completed	Virtual Reality for Pain Management and Patient Satisfaction During Outpatient Hysteroscopy NCT06463210	Hospital Universitario 12 de Octubre	N/A
Completed	The Effect of Exercises of Different Intensity Applied After Total Knee Arthroplasty on Exercise-Induced Hypoa NCT05781230	Hacettepe University	N/A
Withdrawn	Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low NCT05082155	University of California, San Diego	Phase 4
Completed	Shotblocker and Breastfeeding on Pain/Comfort During Heel Lance NCT05246787	Dokuz Eylul University	N/A
Completed	Non-pharmacological Methods in Pain Managment During Heel Stick in Preterm Infants NCT05281367	Negarin Akbari	N/A
Completed	Influence of Kinesiophobia on the Excitability of Connections Parieto-frontal During a Pointing Movement in Hu NCT06125613	Universite du Littoral Cote d'Opale	N/A
Unknown	The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction NCT06073639	University of Medicine and Pharmacy at Ho Chi Minh City	N/A
Completed	Investigation of the Effect of White Noise Listening on Pain and Comfort During Invasive Interventions in Newb NCT05103800	Batman University	N/A
Completed	Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial NCT05321121	University of California, Irvine	Phase 4
Completed	The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines NCT05476575	Fu Jen Catholic University Hospital	N/A
Completed	EFFECT OF DISTRACTION METHODS ON PAIN AND ANXIETY DURING INTRAMUSCULAR INJECTION IN CHILDREN NCT06011668	Mersin University	N/A
Completed	The Effect of Touch on Pain and Anxiety During the Bone Marrow Biopsy Procedure NCT04935775	Dartmouth-Hitchcock Medical Center	N/A
Unknown	Opioid-free Anesthesia in Laparoscopic Cholecystectomies NCT05089526	Aretaieion University Hospital	N/A
Recruiting	fMRI and IVCM Cornea Microscopy of CXL in Keratoconus NCT04439552	Boston Children's Hospital	—
Unknown	Cervical Erector Spinae Block Versus Interscalene Block for Shoulder Surgery NCT04435236	Ataturk University	N/A
Unknown	Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment NCT05383820	University of Guadalajara	Phase 4
Unknown	PENG: an Estimation of ED50 in Neck of Femur Fracture NCT05095025	University College Cork	N/A
Completed	Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI NCT05069350	Research Institute of Ophthalmology, Egypt	EARLY_Phase 1
Completed	Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain NCT05005871	Udayana University	N/A
Completed	Dexametasone Versus Dexametasone Plus Dexmedetomidine in Nerve Blocks NCT04875039	University of Chile	Phase 4
Unknown	Comparison Between Pupillometry and the Numerical Rating Scale NCT05019898	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	N/A
Completed	Ultrasound-guided Deep Versus Superficial Continuous Serratus Anterior Plane Block for Pain Management in Pati NCT04575272	Assiut University	N/A
Unknown	The Effectiveness of Acupuncture for Complications in Critically Ill Patients NCT04950738	China Medical University Hospital	N/A
Completed	Impact of Modern Art Therapy on Patients' Anxiety and Pain During the Waiting Time in an Emergency Department NCT04997434	Olivier Hugli	N/A
Unknown	Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries NCT05283434	Children's Hospitals and Clinics of Minnesota	Phase 2 / Phase 3
Unknown	Pharmacist-led Pharmacogenomic Clinical Service Within the Program of All-inclusive Care for the Elderly NCT04971902	Tabula Rasa HealthCare	—
Completed	Pain Felt During Removal of the Products From Infant's Skin Used in Nasogastric Tube Fixation NCT05064072	Marmara University	N/A
Completed	Pericapsular Nerve Group Block for Hip Fractures NCT04882384	Jacobi Medical Center	N/A
Completed	Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean S NCT04932083	Benha University	N/A
Completed	Effect of Iontophoresis vs. Ultrasound and Iontophoresis in Plantar Fasciitis". Plantar Fasciitis" NCT04917406	University of Seville	N/A
Recruiting	Brain Mechanisms Supporting Cannabis-induced Pain Relief NCT04982965	University of California, San Diego	EARLY_Phase 1
Completed	Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patient NCT04871061	Cigli Regional Training Hospital	N/A
Withdrawn	Preoperative Fluoroscopy Guided Hip Articular Branch Blocks and Analgesic Outcomes Following Hip Arthroscopy NCT04538105	Rush University Medical Center	N/A
Completed	Online Mindfulness-based Intervention to Prevent Chronic Pain NCT04848428	Florida State University	N/A
Unknown	Antinociceptive Effect of Transauricular Electrical Vagal Nerve Stimulation NCT04448990	University Medicine Greifswald	N/A
Completed	Effect Of Virtual Reality Glasses Used During Splint Application On Children's Pain And Anxiety Levels. NCT05281133	Karabuk University	N/A
Completed	Stellate Ganglion Block in Control of Arrhythmia in Laparoscopic Cholecystectomy NCT04837495	Assiut University	N/A
Unknown	Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks NCT04852484	Aretaieion University Hospital	N/A
Completed	Ultrasound-guided Block of the Supraclavicular Nerves in Clavicular Fractures NCT04685291	Eckehart SCHÖLL	N/A
Completed	Prehospital Analgesia in Adults Using Inhaled Methoxyflurane : A Feasibility Study NCT04287803	Ottawa Hospital Research Institute	Phase 4
Completed	Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block f NCT04854395	Regionshospitalet Silkeborg	Phase 4
Unknown	The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS NCT04829409	Huazhong University of Science and Technology	N/A
Unknown	Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine NCT04858711	Aretaieion University Hospital	N/A
Unknown	Ibuprofen Plus Acetaminophen for Enhanced Pain Reduction NCT04630834	New York City Health and Hospitals Corporation	Phase 4
Completed	The Effects of Auditory Interventions on Comfort and Mothers' Anxiety in Newborns NCT05079594	Akdeniz University	N/A
Completed	Pain Reduction With Topical Bromfenac Versus Artificial Tear After Intravitreal Injection. NCT06130384	Wills Eye	Phase 4
Completed	OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients NCT04694300	Hersh, Elliot V., DMD, MS, PhD	Phase 4
Completed	ESP in Breast Surgery Due to Cancer NCT04726878	Medical University of Lublin	Phase 4
Completed	Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial NCT04274530	McMaster University	N/A
Completed	Use of Virtual Reality in Pain Management in Hospitalized Patients NCT05545033	Changi General Hospital	N/A
Completed	Analgesic Efficacy of Orally Administered VTS-K for Pain Management NCT04702555	Antonios Likourezos	—
Completed	Intrathecal Nalbuphine is a Comparable Safer Alternative to Fentanyl for Intraoperative Pain Management During NCT04689217	Cairo University	N/A
Completed	IV Dexmedetomidine vs Oral Gabapentin and Their Combination for Postoperative Analgesia in Cancer Patients Und NCT06354478	National Cancer Institute, Egypt	N/A
Completed	Nerve Stimulation Using a TENS to Provide Pain Relief During Surgery for Overactive Bladder NCT05330117	University of Rochester	N/A
Unknown	Dose Finding Study of STR-324 NCT04582786	Alaxia SAS	Phase 2
Terminated	Intraoperative Methadone in Children Undergoing Surgery NCT04680286	University of Aarhus	Phase 3
Unknown	The Effect of Acupressure on Acute Pain, Stress and Satisfaction During Venipuncture NCT04665518	Istanbul Sabahattin Zaim University	N/A
Unknown	Lidocaine and Magnesium and Ketamine in Gynecological Surgery NCT04622904	Aretaieion University Hospital	N/A
Completed	The Effect of Halophyte-based Cream on Pain and Itch NCT04635254	Aalborg University	N/A
Completed	A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre NCT04863807	Imperial College Healthcare NHS Trust	—
Completed	Intraoperative Sublingual Sufentanil for Acute Pain in the Ambulatory Surgery Center NCT04387136	University of Minnesota	Phase 4
Terminated	Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine NCT03127592	Apsen Farmaceutica S.A.	Phase 3
Completed	Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain NCT04571515	Mylan Inc.	Phase 2
Recruiting	RCT of Pain Perception With Fast and Slow Tenaculum Application NCT05458037	Women and Infants Hospital of Rhode Island	N/A
Completed	Changes in Affective Pain Processing in Human Volunteers NCT04280796	susanne becker	N/A
Completed	Adjunct VR Pain Management in Acute Brain Injury NCT04356963	University of Maryland, Baltimore	N/A
Terminated	PVB vs Ketamine/Lidocaine in Rib Fracture Patients NCT04413799	George Washington University	EARLY_Phase 1
Completed	Efficacy of Ketamine in Post Anesthesia Recovery Room NCT04701008	University of Alberta	—
Unknown	COping With PAin Through Hypnosis, Mindfulness and Spirituality NCT04491630	ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida	N/A
Completed	Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care NCT05254470	ZetrOZ, Inc.	—
Completed	Music to Reduce Patient Reported Pain During Intrauterine Device (IUD) Placement in the Office NCT05068245	Rutgers, The State University of New Jersey	N/A
Unknown	Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer NCT04042545	Tetra Bio-Pharma	Phase 2
Withdrawn	Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries NCT04523623	Washington University School of Medicine	N/A
Completed	Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses NCT04458467	University of California, San Diego	N/A
Unknown	Postoperative Pain Scores and Opioid Consumption in Video Assisted Thoracic Surgery NCT04459923	Ataturk University	N/A
Recruiting	Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphe NCT06514365	Germans Trias i Pujol Hospital	N/A
Completed	Bilateral Erector Spinae Plane Block (ESPB) in Laparoscopic Cholecystectomies NCT04587973	Aretaieion University Hospital	N/A
Unknown	Low Dose Methoxyflurane for Pain Relief During Minor Out-patient Urologic Procedures NCT04412642	Sunnybrook Health Sciences Centre	Phase 4
Completed	Intraosseous Morphine in Primary TKA NCT04388111	The Methodist Hospital Research Institute	Phase 4
Unknown	Can Warm Skin Disinfection Reduce the Pain Peripheral Central Catheter Application in Premature Babies? NCT04458441	Zekai Tahir Burak Women's Health Research and Education Hospital	N/A
Completed	Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption NCT04123873	Naestved Hospital	Phase 4
Completed	Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients NCT04271917	University of Tennessee	Phase 3
Completed	Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers NCT04252833	Lotus Clinical Research, LLC	Phase 1
Completed	Virtual Reality for Pain and Anxiety Distraction Strategy on Office Hysteroscopy NCT04721587	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	N/A
Completed	The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia NCT04662827	Medical University of Graz	N/A
Completed	Water-friendly Virtual Reality and Brief Thermal Pain NCT04245475	University of Washington	N/A
Terminated	Liposomal Bupivacaine vs Peripheral Nerve Block NCT03922620	Geisinger Clinic	Phase 4
Unknown	Sufentanil Intranasal NCT04137198	Centre Hospitalier Universitaire Saint Pierre	Phase 4
Unknown	Regional Anesthesia for Cardiothoracic Enhanced Recovery NCT03781440	Stanford University	N/A
Completed	Nurse Initiated Acupressure for Pain Management NCT04044716	Wake Forest University Health Sciences	N/A
Completed	Sublingual Sufentanil vs Intravenous Fentanyl for Acute Pain in the Ambulatory Surgery Center NCT04177862	University of Minnesota	Phase 4
Unknown	Different Modalities of Analgesia in Open Heart Surgeries in Mansoura University NCT04223219	Mansoura University	Phase 4
Unknown	The Frequency Of Sodium Hypochlorite Extrusion During Endodontic Treatments NCT04262362	Bulent Ecevit University	—
Unknown	Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Vol NCT04175743	Lotus Clinical Research, LLC	Phase 1
Completed	Effect of Reflexology on Pain Management in Newborns NCT05235893	Marmara University	N/A
Completed	Is it Necessary to Fix Mesh in Laparoscopic Hernia Repair NCT05152654	Hitit University	N/A
Completed	The Effects of Objective Estimation of Pain Response NCT04114851	Göteborg University	N/A
Terminated	Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain NCT03959852	Mercy Health Ohio	Phase 4
Unknown	Nutraceuticals and Functional Foods NCT05509075	University of Catanzaro	—
Unknown	Bilateral Quadraus LUMBORUM Block in Patients Under Going Cystectomy NCT03853460	Assiut University	N/A
Completed	Preoperative Psychosocial Support for Postoperative Recovery and Health: Mechanistic Substudy NCT04520958	University of Utah	N/A
Unknown	Inhaled Methoxyflurane for Pain Management in Nasal Bone Fracture Reduction NCT04332159	Université de Sherbrooke	Phase 3
Completed	Ketamine to Improve Recovery After Cesarean Delivery - Part 1 NCT04037085	Grace Lim, MD, MS	Phase 2
Completed	Transversus Thoracic Muscle Plane Block for Open Heart Surgery NCT04094532	Ataturk University	N/A
Withdrawn	Evaluation of Dronabinol For Acute Pain Following Traumatic Injury NCT03928015	CommonSpirit Health	Phase 2
Terminated	Eye Tracking as a Biomarker of Cannabis Effects NCT04100590	New York State Psychiatric Institute	Phase 2
Completed	Comparison of Morphine With Nalbuphine in a Multimodal Approach for Pain Relief in Patients Undergoing Gynecol NCT06191770	Aga Khan University Hospital, Pakistan	N/A
Recruiting	A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes NCT03695887	University of Manitoba	EARLY_Phase 1
Completed	How to Develop a Training Program for Nurses in Ultrasound Guided Femoral Nerve Block NCT04659395	Sykehuset i Vestfold HF	N/A
Unknown	Cognitive and Motor Benefits of Standing NCT03944564	Science and Research Centre Koper	N/A
Completed	Assessing Opioid Care Practices Using CPV Patient Simulation Modules NCT04080037	Qure Healthcare, LLC	N/A
Unknown	Oral Steroid in Controlling Pain After TKA NCT04244695	Thammasat University	Phase 4
Unknown	Olfactive Stimulation Interventions With Mothers' Milk on Preterm Pain Response NCT04062513	St. Justine's Hospital	N/A
Completed	Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring NCT03967197	Centre hospitalier de l'Université de Montréal (CHUM)	Phase 2 / Phase 3
Completed	Ice Immersion Using Virtual Reality & Augmented Reality NCT04196686	Stanford University	N/A
Completed	The Impact of Music on Nociceptive Processing NCT04087564	Brigham and Women's Hospital	N/A
Completed	Pawsitive Impacts of Therapy Dog Visits NCT04727749	University of Saskatchewan	N/A
Unknown	RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe) NCT03770208	Western University, Canada	N/A
Unknown	Single Dose Adductor Canal Block vs SPANK Block for TKA NCT03502889	San Antonio Uniformed Services Health Education Consortium	N/A
Completed	Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction NCT03893175	University of Pennsylvania	Phase 1
Completed	The Effect of Music Played and Acupressure Application on Pain and Anxiety in Women Undergoing Gynecological E NCT04356820	Adiyaman University Research Hospital	N/A
Completed	Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases NCT04677985	Memorial University of Newfoundland	N/A
Completed	PENTHROX™ in the Canadian Emergency Department (ED) NCT03868436	Purdue Pharma, Canada	Phase 4
Withdrawn	Duration of Analgesia With Dexmedetomidine and Ropivacaine in Brachial Plexus Block NCT03385967	University of Florida	Phase 4
Completed	Perioperative Pregabalin in Ureteroscopy: a Pilot NCT03927781	University of Missouri-Columbia	Phase 3
Unknown	Noninvasive Brain Stimulation for Pain Relief NCT04283643	University of Virginia	N/A
Unknown	The Effectiveness of Music on Pain and Anxiety in IUD Insertion NCT03828760	McMaster University	N/A
Completed	The Role of Time Interval Elimination on Pain Control of Preterm Infants by Sucrose Administration NCT05465694	Gulhane School of Medicine	N/A
Unknown	Erector Spinae Plane Block in Cardiac Surgery NCT03997019	Assiut University	N/A
Completed	Vibration Analgesia in Propofol Infusion During Anesthesia Induction NCT03509857	Montefiore Medical Center	N/A
Withdrawn	Exercise and Pain in Non-Hispanic Blacks and Whites NCT03609957	Georgia State University	N/A
Unknown	Low Dose Lignocaine Injections as a Treatment Option for Acute Lumbosacral Radiculopathy NCT04215757	All India Institute of Medical Sciences, Rishikesh	N/A
Completed	Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterio NCT04178109	KAT General Hospital	Phase 2
Completed	Ethyl Chloride for NPWT NCT04635696	ProMedica Health System	Phase 4

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