NCT06737939

Periprostatic Nerve Block vs. Intravenous Ibuprofen for Pain Management During Transrectal Prostate Biopsy

Periprostatic Nerve Block vs. Intravenous Ibuprofen for Pain Management During Transrectal Prostate Biopsy: A Prospective Comparative Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 128 (actual)
• Sponsor: University of Gaziantep · Academic / Other
• Sex: Male
• Age: 45 Years – 82 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to compare the efficacy of intravenous ibuprofen with peri-prostatic nerve block in pain control during prostate biopsy and to investigate factors influencing pain scores.

Detailed description

This study aimed to compare the efficacy of intravenous (IV) ibuprofen with periprostatic nerve block (PPNB) in controlling pain during prostate biopsy, a common procedure used to diagnose prostate cancer. The study also aimed to investigate factors influencing pain perception during the procedure, such as prostate-specific antigen (PSA) levels, prostate volume, and comorbidities.

Conditions

• Pain, Acute

Interventions

Type	Name	Description
OTHER	intravenous ibuprofen	A systemic analgesic (NSAID) administered intravenously for pain management during prostate biopsy, without the need for additional invasive interventions.
OTHER	periprostatic nerve block	A local anesthetic injection targeting the periprostatic nerves to provide direct pain relief during the biopsy procedure, considered the gold standard for pain management in prostate biopsies.

Timeline

• Start date: 2023-06-01
• Primary completion: 2023-12-01
• Completion: 2023-12-30
• First posted: 2024-12-17
• Last updated: 2024-12-17

Locations

1 site across 1 country: Turkey (Türkiye)