NCT05834023

Bupivacaine Versus Bupivacaine Plus Lidocaine in Infraclavicular Block

Comparison Between Bupivacaine 0.5% Versus Bupivacaine 0.25% Plus Lidocaine 1% in Ultrasound-guided Infraclavicular Block: a Prospective Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Hospital de San Carlos Dr. Benicio Arzola Medina · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In this study, the investigators will compare two different anesthetic solutions in the infraclavicular block in patients having forearm, wrist, and hand surgery. The solutions will be bupivacaine 0.5% versus bupivacaine 0.25% plus lidocaine 1%, both associated with epinephrine 5 mcg/ml and dexamethasone 4 mg. The main objective of this investigation is to demonstrate that using higher concentrations of bupivacaine alone results in a significant block duration increase compared with the mixture of bupivacaine and lidocaine.

Conditions

• Pain, Acute
• Postoperative Pain
• Analgesia

Interventions

Type	Name	Description
DRUG	Bupivacaine-Lidocaine	Infraclavicular block with 35 ml of the following anesthetic solution: Bupivacaine 0.25% + Lidocaine 1% + dexamethasone 4 mg + epinephrine 5 mcg/ml
DRUG	Bupivacaine	Infraclavicular block with 35 ml of the following anesthetic solution: Bupivacaine 0.5% + dexamethasone 4 mg + epinephrine 5 mcg/ml

Timeline

• Start date: 2023-05-02
• Primary completion: 2023-12-29
• Completion: 2024-01-05
• First posted: 2023-04-27
• Last updated: 2024-01-17

Locations

1 site across 1 country: Chile