NCT06408519

Open-Label Placebo for Non-Specific Pain in the ED

Open -Label Placebo for Non-specific Pain in the Emergency Department: Study Protocol for a Mixed-method Randomised Control Feasibility Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 57 (actual)
• Sponsor: Bruno Minotti · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to assess whether an intervention with open-label placebo (OLP) for non-specific pain in the emergency department is feasible.

Detailed description

This project is a collaboration between the Emergency Department at the University Hospital of Basel and the Faculty of Psychology at the University of Basel. The investigation will analyze whether an intervention consisting of open-label placebo tablets is feasible for patients with non-specific pain in the emergency department. Open-label placebos are administered without deception, meaning the patients are aware they are taking a placebo. Patients will be randomized into intervention group (OLP) or control group (treatment as usual) with ibuprofen. The study duration for patients is 30 days.

Conditions

• Pain, Acute

Interventions

Type	Name	Description
OTHER	Placebo (open-label)	P-Tabletten weiss 10mm (Lichtenstein, Zentiva) pills 3x/day
DRUG	Ibuprofen 400 mg	Ibuprofen pills 3x/day

Timeline

• Start date: 2024-05-23
• Primary completion: 2026-02-13
• Completion: 2026-02-13
• First posted: 2024-05-10
• Last updated: 2026-03-09

Locations

1 site across 1 country: Switzerland