NCT04701008

Efficacy of Ketamine in Post Anesthesia Recovery Room

Observational Study of the Efficacy of Ketamine for Rescue Analgesia in the Post Anesthesia Recovery Room

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 143 (actual)
• Sponsor: University of Alberta · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Observational study to assess efficacy of IV ketamine bolus when used in the post anesthesia recovery unit for uncontrolled pain despite use of opioids.

Detailed description

In this observational study, the investigators will monitor all patients with significant pain after any non-cardiac surgical intervention at the University of Alberta Hospital. After receiving an adequate dose of potent opioids (hydromorphone, morphine), the participants will receive up to 0,2-0,25 mg/kg IV ketamine bolus. In our center these boluses are given with 10-20mg increments. The adequate dose of opioids will be determined by the attending anesthesiologist, depending on what patients received intraoperatively and on their comorbidities. Pain scores will be assessed before and after administration of this drug. The incidence of any side effect after ketamine administration will be documented.

Conditions

• Pain, Postoperative
• Ketamine Adverse Reaction
• Pain, Refractory
• Pain, Intractable
• Pain, Acute

Interventions

Type	Name	Description
DRUG	Ketamine	IV ketamine - 10mg bolus may be repeated repeated 2-3 times depending on clinical judgement

Timeline

• Start date: 2020-09-01
• Primary completion: 2021-05-28
• Completion: 2021-05-28
• First posted: 2021-01-08
• Last updated: 2024-09-19

Locations

1 site across 1 country: Canada