NCT05069350

Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI

A Double Blinded Randomized Controlled Study of Topical Anaesthetics Oxybuprocaine Versus Bupivacaine 0.5% in Intravitreal Injections

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Research Institute of Ophthalmology, Egypt · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Accepted

Summary

comparing two local anaesthetic agents, Bupivacaine 0.5% versus Oxybuprocaine used topically to provide surface anaesthesia before IVI procedures.

Detailed description

In preparation zone, we will cannulate the patients, connect them to the pulse oximetry and we will start providing appropriate surface anaesthesia for an adequate period of time before the patient administration of the injection, by applying the anaesthetic agents, 3 times with 5 minutes interval, for 15 minutes and then waitng the injection All patients are informed that they are going to receive topical anaesthetic agent before the IVI. pain is monitored during the injection by using the 11 points verbal numerical pain scaling as zero is for no pain and 10 is for severe unbearable pain.

Conditions

• Pain, Acute

Interventions

Type	Name	Description
DRUG	bupivacaine 0.5% and oxubuprocaine	using each drug as surface anesthesia before intravitreal injections

Timeline

• Start date: 2021-09-01
• Primary completion: 2022-08-01
• Completion: 2022-08-01
• First posted: 2021-10-06
• Last updated: 2022-09-13

Locations

1 site across 1 country: Egypt