| Withdrawn | Effects of Cannabidiol on Psychiatric Symptoms, Cognition, and Cannabis Consumption in Cannabis Users With Rec NCT03883360 | University of Maryland, Baltimore | Phase 2 |
| Not Yet Recruiting | Smart Talk: Cannabis Awareness and Prevention Curriculum Evaluation NCT07357454 | Stanford University | N/A |
| Not Yet Recruiting | Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills NCT06422299 | University of Washington | N/A |
| Not Yet Recruiting | Research Investigating Drug Effects-2 (RiDE-2) NCT06758596 | University of Illinois at Chicago | EARLY_Phase 1 |
| Not Yet Recruiting | Behavioral Pharmacology of THC and Beta-Myrcene NCT05432284 | Johns Hopkins University | Phase 1 |
| Not Yet Recruiting | Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance NCT06351540 | Johns Hopkins University | Phase 1 |
| Not Yet Recruiting | Effects of Cannabis Species Labeling and Marketing on Perceptual, Subjective and Objective Use Outcomes (Aim 2 NCT07513337 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Not Yet Recruiting | Evaluating the Impact of Psychotherapeutic Advertising Claims on Cannabis Purchasing NCT07216911 | Trustees of Dartmouth College | N/A |
| Not Yet Recruiting | Perceptions of Proposed Warnings for Cannabis Edibles Packaging NCT07496489 | Wake Forest University Health Sciences | N/A |
| Not Yet Recruiting | Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum NCT07489443 | University of Pittsburgh | N/A |
| Not Yet Recruiting | Joint Effort 2.0 : Evaluation Among General Population NCT07524985 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Recruiting | Neuroimaging of Adolescent Cannabis Use Treatment NCT07340554 | Indiana University | N/A |
| Not Yet Recruiting | Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Us NCT07459270 | Elazığ Mental Health and Diseases Hospital | — |
| Not Yet Recruiting | A Brief Cannabis Use Psychoeducation Intervention for Eating Disorder Patients NCT07387965 | St. Joseph's Healthcare Hamilton | N/A |
| Not Yet Recruiting | Acute Effects of Cannabis on Cognition and Affect NCT07296874 | Washington State University | Phase 2 |
| Recruiting | Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia NCT07196462 | Vanderbilt University Medical Center | N/A |
| Recruiting | Impact of Cannabis Use During Third Molar Surgery NCT07423195 | University of Michigan | — |
| Enrolling By Invitation | Testing the Effects of Cann'App, a Digital Intervention for Cannabis Harm Reduction NCT07157540 | Jacques Gaume | N/A |
| Enrolling By Invitation | Investigating Cannabis Use Parameters on Anesthesia and Inflammation in Lumbar Spinal Surgeries NCT07354412 | University of Missouri-Columbia | — |
| Recruiting | Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use NCT07011615 | University of Washington | N/A |
| Not Yet Recruiting | THC + CBD and Memory Study NCT04855526 | Hartford Hospital | EARLY_Phase 1 |
| Not Yet Recruiting | Skills for Talking About Cannabis for Families of Young Adults With Psychosis NCT06961877 | University of Washington | N/A |
| Recruiting | Study of Oral Fluid Testing Approach NCT06891235 | Boston Children's Hospital | — |
| Not Yet Recruiting | Warrior CARE: Cannabis Behavioral Health NCT06381180 | Wayne State University | Phase 1 / Phase 2 |
| Recruiting | Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes. NCT07063589 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Recruiting | Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS) NCT07227324 | HealthPartners Institute | — |
| Recruiting | Culturally Adapted EAET-H for Chronic Pain Patients Using Medical Cannabis in Israel - A Pilot Study NCT07168707 | Reuth Rehabilitation Hospital | N/A |
| Recruiting | Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration NCT05999383 | University of California, San Francisco | Phase 2 |
| Completed | Gastric Ultrasound Assessment for Patients Taking Cannabis NCT06567873 | Hospital for Special Surgery, New York | — |
| Recruiting | Cannabis-Tobacco Co-Use Treatment Study NCT06883162 | Medical University of South Carolina | Phase 3 |
| Recruiting | Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat) NCT06699251 | RAND | N/A |
| Recruiting | Effect of Cannabis on E-Cigarette Use Behavior NCT06609109 | Johns Hopkins University | Phase 1 |
| Recruiting | Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis NCT07001878 | Nova Scotia Health Authority | Phase 4 |
| Suspended | Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults NCT06077292 | University of California, San Francisco | N/A |
| Recruiting | Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults NCT06743373 | University of Pittsburgh | N/A |
| Recruiting | Neural and Psychiatric Consequences of Cannabis Use in Adolescents NCT06941298 | University of Miami | N/A |
| Recruiting | Cannabis, Linked Emotions, and Adolescent Risk Study NCT06576076 | Massachusetts General Hospital | N/A |
| Recruiting | Perceptual Influences From Smoking Cannabis: an Experimental Study NCT06588582 | University of Colorado, Boulder | N/A |
| Recruiting | Effect of Cannabis on Cigarette Use Behavior NCT06609083 | Johns Hopkins University | Phase 1 |
| Recruiting | HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention) NCT06513819 | Yale University | Phase 1 |
| Not Yet Recruiting | Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care NCT04146714 | Prof. Dagmar M. Haller | N/A |
| Recruiting | Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development NCT06379971 | University of Colorado, Denver | Phase 1 |
| Not Yet Recruiting | MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education NCT06553196 | California State University, Northridge | N/A |
| Recruiting | The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles NCT05602649 | Johns Hopkins University | Phase 1 |
| Completed | Cannabis Edibles Packaging Imagery Experiment NCT06358144 | Wake Forest University Health Sciences | N/A |
| Recruiting | Stress and Resilience NCT06457841 | University of Washington | N/A |
| Recruiting | Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults NCT05991882 | Kaiser Permanente | N/A |
| Completed | Cannabis Edibles Packaging Descriptors Experiment NCT06171399 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Study on Regulated Cannabis Sales in Pharmacies NCT06120855 | University of Bern | N/A |
| Completed | An App to Reduce Cannabis Use Among Emerging Adults NCT05824754 | University of Michigan | N/A |
| Recruiting | Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (E NCT06259916 | Colorado State University | N/A |
| Completed | Cannabis and Cancer, an Online Training for Oncology Nurses NCT05663346 | Ciusss de L'Est de l'Île de Montréal | N/A |
| Completed | Acute Effects of Cannabis on Everyday Life Memory NCT05488509 | Washington State University | Phase 2 |
| Recruiting | Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use NCT05345951 | Penn State University | N/A |
| Active Not Recruiting | TECH App Marijuana Use Intervention for Court-Involved Adolescents NCT05979272 | Northwestern University | N/A |
| Completed | Culturally Tailored Cannabis Use Disorder App NCT05566730 | University of Houston | N/A |
| Completed | Investigating Real-world Stress-related Mechanisms in Heavy Cannabis Users NCT05833230 | Yale University | N/A |
| Recruiting | Cannabis' Impact on Alcohol Consumption NCT05389930 | Brown University | Phase 2 |
| Withdrawn | Cannabis Use on Sedation for Oral Surgery Procedures NCT05873465 | University of Oklahoma | Phase 4 |
| Completed | Joint Effort 2.0: a Mobile Application With University Students NCT05620433 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Unknown | Effect of Cannabidiol (CBD) on Vision and Driving NCT06322303 | Universidad de Granada | EARLY_Phase 1 |
| Recruiting | CARS: Cannabis and Alcohol Reduction Study NCT05486234 | Medical University of South Carolina | N/A |
| Recruiting | Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder NCT05396638 | University of Colorado, Denver | N/A |
| Completed | Cannabis Use in Pregnancy and Downstream Effects on Maternal and Infant Health NCT05309226 | Ottawa Hospital Research Institute | — |
| Completed | Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit NCT05521321 | Stanford University | N/A |
| Unknown | Alerta Cannabis: Evaluation of Web-based Tailored Intervention NCT05849636 | University of Seville | N/A |
| Withdrawn | Warrior CARE: Naturalistic Observation and Harm Reduction NCT05386862 | Wayne State University | N/A |
| Recruiting | SV2A in Older Adults NCT05465538 | Yale University | Phase 1 / Phase 2 |
| Suspended | Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexi NCT04001010 | Tetra Bio-Pharma | Phase 3 |
| Recruiting | Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking NCT03909477 | Western University, Canada | — |
| Completed | A Trial of Guanfacine-er for Cannabis Use Disorder NCT05273567 | New York State Psychiatric Institute | Phase 2 |
| Recruiting | Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls W NCT05445180 | Douglas Mental Health University Institute | N/A |
| Completed | Alcohol and Cannabis Co-Use and the Gut-Brain Axis NCT04998006 | University of Colorado, Denver | — |
| Recruiting | Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders NCT05064319 | Medical University of South Carolina | Phase 2 |
| Active Not Recruiting | Breathwork-assisted Treatment for Cannabis Use Disorder NCT05219825 | Elias Dakwar | N/A |
| Recruiting | Effect of Extended Cannabis Abstinence on PTSD Symptoms NCT05162651 | Centre for Addiction and Mental Health | N/A |
| Completed | Alcohol and Cannabis Concentrates Co-Administration NCT05999344 | University of Colorado, Denver | N/A |
| Unknown | Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers NCT05235503 | Leiden University Medical Center | Phase 4 |
| Completed | Stress-Reactivity and Cannabis Use in Cannabis-Using Older Adults NCT05072795 | Medical University of South Carolina | N/A |
| Completed | Joint Effort Study NCT05099016 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Mindsets and the Effectiveness of a Brief Intervention - Replication NCT05167097 | University of Konstanz | N/A |
| Completed | Quantification of Cannabinoids and Comparison to Post-Surgical Pain Medication Requirements and Surgical Outco NCT04988490 | University of Colorado, Denver | — |
| Unknown | Environment and Lung Cancer NCT05119244 | Centre Chirurgical Marie Lannelongue | N/A |
| Completed | Aging and Marijuana: Benefits, Effects, and Risks NCT05188404 | University of Colorado, Boulder | — |
| Completed | CanCope: Digital Intervention for Coping With Cannabis Craving NCT05328362 | Trustees of Dartmouth College | N/A |
| Completed | N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use NCT04627922 | Ellen Herbst | Phase 4 |
| Recruiting | Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression NCT04935619 | Centre for Addiction and Mental Health | N/A |
| Completed | Social Media Intervention - Physical Activity NCT04901910 | University of Michigan | N/A |
| Completed | Cannabis Tolerance Break Resource Study: T-Break Guide NCT05382273 | University of Vermont | — |
| Completed | Haloperidol for the Treatment of Nausea and Vomiting in the ED NCT04764344 | Western Michigan University School of Medicine | Phase 4 |
| Completed | Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase) NCT04567238 | Duke University | N/A |
| Completed | Reward and Drug Effects on Mood and Brain Response NCT04512365 | University of Illinois at Chicago | EARLY_Phase 1 |
| Enrolling By Invitation | Tobacco-Concurrent Addictions in At-Risk Youth in Ottawa NCT04812613 | Ottawa Hospital Research Institute | — |
| Active Not Recruiting | Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity NCT04800159 | University of California, San Diego | Phase 2 |
| Completed | Does Cannabidiol Attenuate the Acute Effects of ∆9-tetrahydrocannabinol Intoxication in Individuals Diagnosed NCT04605393 | King's College London | N/A |
| Withdrawn | Health Condition of Cannabis Consumers in the Canadian Population NCT03987347 | Jewish General Hospital | — |
| Completed | Prospective Evaluation on Cognitive Function and Its Associated Genetic Vulnerability in Cannabis Users NCT04373525 | The University of Hong Kong | — |
| Terminated | Intergenerational Effects of Paternal Periconceptional Cannabis and Other Drug Use (EPIC) NCT04436055 | Duke University | — |
| Active Not Recruiting | Effects of Pregnancy-associated Hormones on THC Metabolism in Women NCT04374773 | University of Washington | Phase 4 |
| Completed | Brief Intervention Combined With Health Coaching Via Social Media for Cannabis Use NCT04316741 | University of Michigan | N/A |
| Unknown | Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment NCT04841655 | Institut Català d'Oncologia | — |
| Unknown | Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer NCT04042545 | Tetra Bio-Pharma | Phase 2 |
| Unknown | Novel Approaches to Assessing Cannabis Impaired Driving (NAACID) NCT06255054 | Colorado School of Public Health | — |
| Completed | Reducing Cannabis Use for Sleep Among Adults Using Medical Cannabis NCT03964974 | University of Michigan | N/A |
| Completed | Social Media Intervention for Cannabis Use in Emerging Adults NCT04187989 | University of Michigan | N/A |
| Completed | Cannabis and Aging NCT05084105 | Thorsten Rudroff | — |
| Suspended | Influence of Tobacco Use on Cannabis Use NCT03766971 | New York State Psychiatric Institute | Phase 2 |
| Unknown | Medical Cannabis Against Chronic Musculoskeletal Pain: a Mixed Methods Study. NCT05210660 | CHU de Quebec-Universite Laval | — |
| Recruiting | Youth Experiences and Health Study NCT03332966 | Finnish Institute for Health and Welfare | — |
| Completed | Exploring the Anti-inflammatory Properties of Cannabis and Their Relevance to Insulin Sensitivity NCT04114903 | University of Colorado, Boulder | — |
| Recruiting | Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use NCT03601026 | Nova Scotia Health Authority | N/A |
| Terminated | An Electronic Intervention to Reduce Cannabis Among Young Adults in Psychiatric Care NCT04174963 | Rhode Island Hospital | N/A |
| Terminated | Eye Tracking as a Biomarker of Cannabis Effects NCT04100590 | New York State Psychiatric Institute | Phase 2 |
| Completed | Personalized Feedback Intervention to Reduce Risky Cannabis Use. NCT04060602 | Centre for Addiction and Mental Health | N/A |
| Completed | VRT as a Biomarker of Cerebellar Dysfunction in Chronic Cannabis Use NCT03662737 | Hospital Clinic of Barcelona | — |
| Completed | Marijuana Effects on Simulated Driving Performance NCT03699540 | Shanna Babalonis, PhD | Phase 1 |
| Completed | Pilot Trial of Contingency Management for Long-Term Cannabis Abstinence NCT03786224 | Massachusetts General Hospital | N/A |
| Completed | Impact of Reduced Cannabis Use on Functional Outcomes NCT03681353 | Duke University | N/A |
| Completed | Do Adolescents and Adults Differ in Their Acute Response to Cannabis? NCT04851392 | University College, London | N/A |
| Completed | Using Implementation Intentions to Reduce Cannabis Use NCT03845842 | University of Manchester | N/A |
| Completed | Impact of Progesterone on Stress Reactivity and Cannabis Use NCT03729869 | Medical University of South Carolina | Phase 2 |
| Unknown | Study of the Cannabis Use of Minors Imprisoned in the PACA Region NCT03659942 | Assistance Publique Hopitaux De Marseille | — |
| Completed | Pharmacokinetics and Pharmacological Effects of a Standardized Cannabis Preparation NCT04841993 | Germans Trias i Pujol Hospital | Phase 1 |
| Unknown | Neural Correlates of Driving and Cannabis NCT03581058 | Unity Health Toronto | Phase 1 |
| Completed | Pain Research: Innovative Strategies With Marijuana NCT03522324 | University of Colorado, Boulder | — |
| Unknown | Mindfulness Meditation and Cannabis Dependence : Therapy Effectiveness NCT03366909 | Central Hospital, Nancy, France | N/A |
| Unknown | Prevalence of Strokes Secondary to a Reversible Cerebral Vasoconstriction Attributable to Cannabis Consumption NCT03379857 | University Hospital, Strasbourg, France | N/A |
| Completed | Reducing the Harmful Effects of Cannabis Use: Finding the Optimal CBD:THC Ratio NCT05170217 | King's College London | N/A |
| Completed | Cannabis Use and Epigenetic Alterations in Human Male Sperm Cells NCT03614637 | Duke University | — |
| Unknown | Cannabis for Opioid Substitution Trial NCT03859089 | Cannabis Research Associates | — |
| Completed | Effect of Lorcaserin on Cannabis Withdrawal and Self-administration NCT03253926 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents NCT03276221 | Massachusetts General Hospital | N/A |
| Completed | Impulsivity and Time Perception NCT03162640 | University Hospital, Strasbourg, France | — |
| Completed | Survey on the Place of Community Pharmacists in the Detection of Cannabis Use: a Student's Point of View NCT03167021 | University Hospital, Clermont-Ferrand | — |
| Completed | A Hybrid Effectiveness-Implementation Trial of a School-Based Teen Marijuana Checkup NCT03111667 | University of Washington | N/A |
| Completed | Effects of Cannabis Administration Routes on Human Performance and Pharmacokinetics NCT02177513 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Completed | Electrophysiological Study of the Functioning of Magnocellular Visual Pathway in Regular Cannabis Users NCT02864680 | Central Hospital, Nancy, France | N/A |
| Active Not Recruiting | Probing the Cannabinoid System in Individuals With a Family History of Psychosis NCT02102113 | Yale University | EARLY_Phase 1 |
| Completed | Community Based Cannabis Cessation Program NCT04989205 | Sorlandet Hospital HF | — |
| Completed | Assessment of Cannabis Craving in Schizophrenia Using Virtual Reality NCT01212081 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis NCT01071616 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Withdrawn | Pilot Study Repetitive Transcranial Magnetic Stimulation (rTMS) in Cannabis Craving NCT01031290 | National Institute on Drug Abuse (NIDA) | Phase 1 |