NCT05162651

Effect of Extended Cannabis Abstinence on PTSD Symptoms

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Centre for Addiction and Mental Health · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This will be a 12-week randomized trial. Outpatients and patients from the Mood and Anxiety program at the Centre for Addiction and Mental Health (CAMH) with a current diagnosis of post-traumatic stressed disorder (PTSD) and cannabis-use disorder (CUD) will be randomized to receive individual motivational interviewing therapy and contingency management (n = 12) or individual motivational interviewing therapy alone (control group, n = 12) after enrolment.

Conditions

• PTSD
• Cannabis Use
• Cognitive Symptom
• Comorbidities and Coexisting Conditions

Interventions

Type	Name	Description
BEHAVIORAL	Contingency-management	In addition to structured assessments at baseline, four, eight and twelve months, subjects randomized to the contingency-management group will receive a contingent bonus if the participants show successful abstinence at the end of weeks 4, 8 and 12.
OTHER	Enhanced usual care	Subjects will receive structured, quantitative assessments at baseline, four, eight and twelve weeks.

Timeline

• Start date: 2022-02-02
• Primary completion: 2024-09-01
• Completion: 2024-09-01
• First posted: 2021-12-17
• Last updated: 2024-04-23

Locations

1 site across 1 country: Canada