| Not Yet Recruiting | A Study on the Efficacy and User Experience of Gamified Intervention for Children With Anisometropic Amblyopia NCT07472231 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | N/A |
| Not Yet Recruiting | VISION-3D: Visual Skills Improvement With On-screen 3D Movies. NCT07301645 | Universitat Politècnica de Catalunya | N/A |
| Not Yet Recruiting | Valproate for the Treatment of Residual Amblyopia NCT07226141 | Boston Children's Hospital | Phase 1 / Phase 2 |
| Recruiting | Evaluation of AmblyoFix for the Treatment of Unilateral Amblyopia in Children NCT07323953 | Eyesight Electronics | N/A |
| Not Yet Recruiting | Morning Versus Evening Patching in Childhood Amblyopia NCT07294599 | Yarmouk University | N/A |
| Not Yet Recruiting | Interactive Binocular Treatment (I- BiT) in Adult Patients With Anisometropic Amblyopia NCT07103473 | Shahid Beheshti University of Medical Sciences | N/A |
| Terminated | Evaluation of AmblyoFix for the Treatment of Unilateral Amblyopia NCT07240311 | Eyesight Electronics | N/A |
| Not Yet Recruiting | Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screenin NCT07112560 | University Hospital, Strasbourg, France | — |
| Recruiting | Ocular Characteristics in Patients With Craniosynostosis NCT06928727 | Centre Hospitalier Universitaire, Amiens | — |
| Recruiting | Amblyopia Treatment for Children Aged 8 to 12 Years NCT07281742 | Retina Foundation of the Southwest | N/A |
| Recruiting | Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision I NCT07417046 | Minia University | N/A |
| Recruiting | Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age NCT06524882 | Jaeb Center for Health Research | Phase 3 |
| Recruiting | Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age NCT06380517 | Jaeb Center for Health Research | Phase 3 |
| Completed | Vision Therapy Outcomes in Amblyopia: Linking Brain Plasticity With Visual Perceptual Skills NCT07437807 | Okan University | — |
| Recruiting | Noninvasive Brain Stimulation in Adult Amblyopia NCT06712849 | Midwestern University | N/A |
| Recruiting | Patch-free Occlusion Therapy NCT05440448 | Retina Foundation of the Southwest | N/A |
| Unknown | Developing Better Computerised Vision Tests (CVTV) NCT06224751 | Guy's and St Thomas' NHS Foundation Trust | — |
| Active Not Recruiting | Comparison of Binocular Spectacle Prescription Versus Patching Therapy in Refractive Amblyopia Patients NCT06739798 | Superior University | N/A |
| Recruiting | Novel Amblyopia Treatment With Virtual Reality Games NCT06049459 | Marjean Kulp | N/A |
| Withdrawn | Docosahexaenoic Acid (DHA) Supplementation in Amblyopia NCT03402789 | Johns Hopkins University | Phase 1 / Phase 2 |
| Unknown | Evaluation of Amblyopia Protocols Using a Dichoptic Gabor Videogame Program NCT06150391 | Hospital de Merida | N/A |
| Withdrawn | Assuring Ophthalmologic Follow up NCT04959422 | Dartmouth-Hitchcock Medical Center | N/A |
| Recruiting | Clinical Data Registry of Amblyopia Patients on Luminopia Treatment NCT06429280 | Luminopia | — |
| Recruiting | Video Treatment for Amblyopia NCT05439200 | Retina Foundation of the Southwest | N/A |
| Completed | Impact of Different Types of Virtual Reality Games on Motion Sickness and Ocular in Adults: A Pilot Study NCT06354309 | He Eye Hospital | N/A |
| Unknown | Real Word Study on Myopia Control With Repeated Red Light Therapy for Ages of 3~6 Years Old NCT05811598 | Beijing Airdoc Technology Co., Ltd. | N/A |
| Recruiting | Rehabilitation Training Games for Children With Amblyopia NCT06372548 | Zhu Dian | N/A |
| Unknown | Treating Amblyopia With CureSight NCT06165705 | Alaska Blind Child Discovery | N/A |
| Completed | Next Generation Home Vision Assessment NCT06428435 | NHS Forth Valley | — |
| Active Not Recruiting | Validation of New Virtual Reality Treatment for Children With Lazy Eye Using the Vedea Amblyopia Therapy (VAT) NCT05620173 | Vedea Healthware BV | N/A |
| Unknown | Access to EyeGlasses for School-aged Children NCT05588362 | Boston Children's Hospital | N/A |
| Recruiting | OCT Eccentric Fixation and Amblyopia in Children NCT05714449 | State University of New York College of Optometry | N/A |
| Recruiting | Effect of Transcranial Magnetic Stimulation on Visual Functions of Adult Amblyopia: a Preliminary Study NCT05393739 | National Taiwan University Hospital | N/A |
| Unknown | Amblyopia and Stereoptic Games for Vision NCT05114252 | Pawel Matusz, PhD | N/A |
| Unknown | Effectiveness of Virtual Reality Training in Amblyopia NCT05732467 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Plasma Biomarker in Amblyopia Patients NCT05705778 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Recruiting | Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games NCT05522972 | Nova Southeastern University | N/A |
| Active Not Recruiting | 5 Years of Eye Screening for ARF in Children Aged <3 Years in Flanders NCT05612568 | Universitaire Ziekenhuizen KU Leuven | — |
| Terminated | NEIVATECH Virtual Reality-based System for Amblyopia NCT04819386 | Increase-Tech | N/A |
| Unknown | OKKO Space Academy to Check Children's Vision at Home NCT05313516 | Moorfields Eye Hospital NHS Foundation Trust | N/A |
| Recruiting | Optical Correction and Visual Functions of Adults With Amblyopia NCT05394987 | Centre for Eye and Vision Research | N/A |
| Unknown | Correction of Anisometropic Amblyopia in Children. NCT05325021 | Benha University | — |
| Completed | Effect of 3D Movie Viewing on Stereopsis in Strabismus and / or Anisometropic Amblyops NCT04315649 | Universitat Politècnica de Catalunya | N/A |
| Completed | OCT-A and Amblyopia NCT05223153 | Minia University | — |
| Unknown | Treatment for Amblyopia Under Binocular Conditions Versus the Standard of Care, Monocular Deprivation Treatmen NCT05185076 | NovaSight | N/A |
| Active Not Recruiting | Validation of the GoCheck Kids® Eye Screeningtest in Infants in Flanders NCT05484453 | Universitaire Ziekenhuizen KU Leuven | — |
| Terminated | Proof of Concept Study of Binocular Videogames Versus Patching for Amblyopia NCT04784390 | Novartis Pharmaceuticals | Phase 1 |
| Active Not Recruiting | The Effect of Early Glasses on the Development of Amblyopia NCT04740593 | Erasmus Medical Center | N/A |
| Completed | CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY NCT04785690 | NovaSight | N/A |
| Completed | Improving the Follow up Rate for Pediatric Patients NCT04837534 | Seva Foundation | N/A |
| Unknown | Changes in Amblyopia Using Optical Coherence Tomography NCT04092361 | Assiut University | — |
| Completed | Gocheck Kids vs. Welch Allyn Spot Vision Screener NCT04321538 | Yale University | — |
| Recruiting | Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia NCT06760910 | Tianjin Eye Hospital | N/A |
| Completed | Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults NCT05957458 | Beijing Airdoc Technology Co., Ltd. | N/A |
| Completed | Screening for 3-D Visual Disorders in Preschool Children NCT05204069 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | A Randomized Trial to Evaluate Sequential vs Simultaneous Patching NCT04378790 | Jaeb Center for Health Research | Phase 3 |
| Completed | Children's Eye Examination and Testing At Home Study NCT06980415 | University Hospital Southampton NHS Foundation Trust | N/A |
| Unknown | Dichoptic Treatment vs. Patching for Moderate Anisometropic Amblyopia NCT04302701 | Cairo University | N/A |
| Unknown | Virtual Reality Game Playing in Amblyopia Therapy NCT04261868 | Hamideh Sabbaghi | N/A |
| Recruiting | Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy NCT04310241 | The Cleveland Clinic | — |
| Withdrawn | Amblyopia and Strabismus Detection Using Retinal Birefringence Imaging NCT03919708 | Rebiscan, Inc. | — |
| Completed | A Patch Free Treatment for Young Children With Amblyopia NCT04086524 | University of Waterloo | N/A |
| Terminated | Bilateral Transcranial Direct Current Stimulation and Ocular Occlusion for Adults With Amblyopia NCT05016830 | University of Chile | N/A |
| Completed | Binocularly Balanced Viewing Study NCT03754153 | Moorfields Eye Hospital NHS Foundation Trust | N/A |
| Withdrawn | Treating Amblyopia in Adults With Interactive Video Games NCT03906994 | Mayo Clinic | N/A |
| Completed | Monocular Action Video Game Treatment of Amblyopia NCT04313257 | Universitat Politècnica de Catalunya | N/A |
| Unknown | A Clinical Trial of Caterna Virtual Reality Facilitating Treatment in Children With Amblyopia NCT04238065 | Guangzhou Shijing Medical Software | N/A |
| Withdrawn | The Effect of Light Deprivation on Visual Functions in Adult Amblyopes NCT02799836 | Boston Children's Hospital | N/A |
| Completed | A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming NCT03066063 | Barron Associates, Inc. | — |
| Terminated | Bilateral and Unilateral Amblyopia Treatment Study NCT03780205 | Salus University | — |
| Completed | Perceptual Learning Treatment for Amblyopia NCT03788031 | The Hong Kong Polytechnic University | N/A |
| Completed | Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska NCT04068129 | Alaska Blind Child Discovery | — |
| Completed | Dichoptic Video Treatment for Amblyopia NCT03825107 | Retina Foundation of the Southwest | N/A |
| Completed | Luminopia One Amblyopia Vision Improvement Study NCT03608150 | Luminopia | N/A |
| Completed | New Visual Acuity and Crowding Tests for Better Detection of Amblyopia NCT03505606 | Anglia Ruskin University | N/A |
| Completed | Eye-tracking Based Amblyopia Training NCT05078099 | NovaSight | N/A |
| Recruiting | Binocular Visual Therapy and Video Games for Amblyopia Treatment. NCT03655912 | Universidad Autonoma de Nuevo Leon | N/A |
| Completed | Exercise Interventions of Eye Muscles Post Strabismus Surgery NCT04303832 | Cairo University | N/A |
| Completed | Comparison of Deviation Types Among Astigmatic Children With Or Without Amblyopia NCT04432181 | Sakarya University | — |
| Completed | Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines NCT03668067 | Alaska Blind Child Discovery | — |
| Completed | Prospective Evaluation of a Smartphone Application, GoCheckKids™, to Detect Amblyopia Risk Factors in Young Ch NCT03447171 | Gobiquity Mobile Health | — |
| Completed | Augmenting Patching Treatment for Amblyopia With Physical Exercise NCT03822806 | Mayo Clinic | N/A |
| Unknown | Patching or Gaming as Amblyopia Treatment? NCT03767985 | Erasmus Medical Center | N/A |
| Suspended | Autostereoscopic Dynamic Near Vision Testing NCT04606355 | Alaska Blind Child Discovery | — |
| Recruiting | Binocular Amblyopia Treatment NCT03288948 | Retina Foundation of the Southwest | N/A |
| Completed | Luminopia One Pilot Study NCT02782117 | Luminopia | N/A |
| Completed | Binocular Dig Rush Game Treatment for Amblyopia NCT02983552 | Jaeb Center for Health Research | N/A |
| Terminated | Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia NCT02687581 | Salus University | N/A |
| Unknown | Light-deprivation Utilized to Mitigate Amblyopia NCT02685423 | State University of New York College of Optometry | N/A |
| Completed | A Comparative Study Between Dissociative Treatment and Binocular Interactive Treatment in Amblyopia NCT03255707 | Ain Shams University | N/A |
| Completed | Evaluation of a Smartphone Application, GoCheckKids™ as a Photo Screening Tool in a Pediatric Population NCT03119675 | Gobiquity Mobile Health | N/A |
| Terminated | Regimens of Intermittent Occlusion Therapy for Amblyopia in Children NCT02767856 | Salus University | N/A |
| Completed | Effect of Peripheral Defocus on Axial Growth in Hyperopes NCT02686879 | Aston University | N/A |
| Unknown | The Use of Interactive Binocular Treatment (I-BiT) for the Management of Anisometropic, Strabismic and Mixed A NCT02810847 | Nottingham University Hospitals NHS Trust | N/A |
| Unknown | Early Vision Screening in High-risk Children NCT02678468 | Far Eastern Memorial Hospital | — |
| Unknown | MRI-based Biomarkers for Predicting Punctate White Matter Lesions in Neonates NCT02637817 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Completed | Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Sc NCT02536963 | Rebiscan, Inc. | — |
| Withdrawn | Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population NCT02655432 | Université de Montréal | — |
| Completed | Will Perceptual Learning Via Video Game Playing Improve Visual Acuity Stereopsis & Fixation Stability in Mild NCT02995174 | The Hong Kong Polytechnic University | N/A |
| Unknown | Transcorneal Electrical Stimulation (TES) for the Treatment of Amblyopia NCT02495935 | Wills Eye | N/A |
| Completed | An Active Approach to Treat Amblyopia: Perceptual Learning and Video Games NCT01115283 | University of California, Berkeley | N/A |
| Active Not Recruiting | Binocular iPad Sub-Study NCT02365090 | Retina Foundation of the Southwest | N/A |
| Completed | Standard Amblyopia Therapy in Adult Amblyopes NCT03341780 | Southern California College of Optometry at Marshall B. Ketchum University | — |
| Unknown | The Role of Interactive Binocular Treatment System in Amblyopia Therapy NCT02740725 | Shahid Beheshti University of Medical Sciences | N/A |
| Terminated | Dichoptic Virtual Reality Therapy for Amblyopia in Adults NCT02246556 | University of California, San Francisco | Phase 1 |
| Withdrawn | Caffeine in Amblyopia Study NCT02594358 | Johns Hopkins University | Phase 1 / Phase 2 |
| Completed | Study of Binocular Computer Activities for Treatment of Amblyopia NCT02200211 | Jaeb Center for Health Research | N/A |
| Completed | Efficacy of Visual Screening in Ontario NCT02458846 | The Hospital for Sick Children | N/A |
| Completed | Efficacy of Over-glasses Patch Treatment for Amblyopia in Children : OPTA Study NCT03080285 | Pusan National University Hospital | N/A |
| Unknown | New Pediatric Patching Method to Improve Compliance NCT02236351 | Baylor College of Medicine | N/A |
| Withdrawn | Visual Functional Connectivity and Visual Improvement After TMS/Binocular Treatment NCT03151200 | University of Manitoba | N/A |
| Terminated | Comparison of AmblyzTM Glasses and Patching for Amblyopia NCT01973348 | Indiana University | N/A |
| Completed | Assessment of Device for Treatment of Amblyopia NCT02003235 | Visior Technologies Ltd. | N/A |
| Completed | Stochastic Resonance Applied to Amblyopia Training and the Plasticity of Brain NCT04213066 | National Cheng-Kung University Hospital | N/A |
| Completed | Binocular Treatment of Amblyopia Before and After Strabismus Surgery NCT01791946 | Massachusetts Eye and Ear Infirmary | N/A |
| Completed | Treatment of Residual Amblyopia With Donepezil NCT01584076 | Boston Children's Hospital | Phase 1 |
| Completed | I-BiT - Evaluation of a Novel Binocular Treatment System (I-BiTTM) in Children With Amblyopia NCT01702727 | Nottingham University Hospitals NHS Trust | Phase 2 |
| Completed | Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptu NCT03109314 | Dennis Levi | Phase 4 |
| Completed | Disinvestment Study of Population-Based Vision Screening in Children NCT01675193 | Erasmus Medical Center | N/A |
| Completed | Vision Screening for the Detection of Amblyopia NCT01430247 | Mladen Busic | N/A |
| Completed | Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner NCT01706991 | Rebiscan, Inc. | — |
| Completed | Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner NCT01832883 | Rebiscan, Inc. | — |
| Completed | Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner NCT01726842 | Rebiscan, Inc. | — |
| Completed | Levodopa for the Treatment of Residual Amblyopia NCT01190813 | Jaeb Center for Health Research | Phase 3 |
| Completed | Thickness of Retinal Layers in Amblyopia NCT01179763 | Samsung Medical Center | — |
| Unknown | Determining the Efficacy of Full-time Occlusion Therapy in Severe Amblyopia at Different Ages NCT02113709 | Mughal Eye Trust Hospital | N/A |
| Completed | Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia? NCT01308307 | Shahid Beheshti University of Medical Sciences | Phase 2 |
| Completed | Increasing Patching for Amblyopia in Children 3 to < 8 Years Old NCT00945100 | Jaeb Center for Health Research | Phase 3 |
| Completed | Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old NCT00944710 | Jaeb Center for Health Research | Phase 3 |
| Completed | Pilot Study to Evaluate Levodopa as Treatment for Residual Amblyopia NCT00789672 | Jaeb Center for Health Research | Phase 2 |
| Completed | Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old NCT00669539 | Jaeb Center for Health Research | — |
| Completed | Comparison of Photorefraction With Cycloautorefraction and Cycloretinoscopy at Emam Hosein Medical Centre in 2 NCT00815581 | Shahid Beheshti University of Medical Sciences | Phase 1 / Phase 2 |
| Terminated | Trial Comparing Patching With Active Vision Therapy to Patching With Control Vision Therapy as Treatment for A NCT00587171 | Jaeb Center for Health Research | Phase 3 |
| Completed | Effectiveness of Telescopic Magnification in the Treatment of Amblyopia NCT00970554 | The Hospital for Sick Children | Phase 1 / Phase 2 |
| Completed | Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children NCT00525174 | Jaeb Center for Health Research | Phase 3 |
| Terminated | Combined Patching-Atropine for Residual Amblyopia NCT00506675 | Jaeb Center for Health Research | Phase 3 |
| Completed | Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds NCT00315328 | Jaeb Center for Health Research | Phase 3 |
| Completed | Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Yea NCT00315302 | Jaeb Center for Health Research | Phase 3 |
| Completed | Trial Comparing Near Versus Distance Activities While Patching for Amblyopia in Children 3 to <7 Years Old NCT00315198 | Jaeb Center for Health Research | Phase 3 |
| Completed | An Active Approach to Treat Amblyopia: Video Game Play NCT01223716 | University of California, Berkeley | N/A |
| Completed | Visual Cortex Stimulation in Patients With Amblyopia NCT00097162 | National Eye Institute (NEI) | Phase 1 |
| Completed | Multimodal Physician Intervention to Detect Amblyopia NCT01109459 | University of Alabama at Birmingham | N/A |
| Completed | Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children NCT00091923 | Jaeb Center for Health Research | Phase 3 |
| Withdrawn | Amblyopia and Neurovascular Coupling in the Retina of Humans NCT00312390 | Medical University of Vienna | N/A |
| Completed | An Evaluation of Treatment of Amblyopia in Children 7 To <18 Years Old NCT00094692 | Jaeb Center for Health Research | Phase 3 |
| Completed | Trial Comparing Daily Atropine Versus Weekend Atropine NCT00094614 | Jaeb Center for Health Research | Phase 4 |
| Completed | Patching for Lazy Eye: Trial to Evaluate Daily Patching Amounts NCT00274664 | City, University of London | Phase 1 |
| Completed | Electronic Recording of Compliance With Occlusion Therapy for Amblyopia NCT00131729 | Erasmus Medical Center | Phase 3 |
| Completed | Trial Comparing Part-time Versus Minimal-time Patching for Moderate Amblyopia NCT00094679 | Jaeb Center for Health Research | Phase 3 |
| Completed | Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia NCT00094744 | Jaeb Center for Health Research | Phase 3 |
| Completed | Amblyopia (Lazy Eye) Treatment Study NCT00001864 | National Eye Institute (NEI) | Phase 3 |
| Completed | Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia NCT00000170 | Jaeb Center for Health Research | Phase 3 |
| Completed | Validation of a Questionnaire Assessing Quality of Life in Children With Amblyopia and Strabismus NCT02880488 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Unknown | Vision In Preschoolers Study (VIP Study) NCT00038753 | National Eye Institute (NEI) | Phase 3 |