NCT03825107

Dichoptic Video Treatment for Amblyopia

Dichoptic Video Treatment for Amblyopia in Children Age 3-7 Years

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: Retina Foundation of the Southwest · Academic / Other
• Sex: All
• Age: 3 Years – 7 Years
• Healthy volunteers: Not accepted

Summary

1. To determine whether watching contrast-rebalanced dichoptic videos is effective in improving visual acuity and reducing interocular suppression in amblyopic children 2. To compare the amount of visual acuity improvement achieved with the videos to tha amount achieved with patching (standard treatment for amblyopia)

Detailed description

Contrast-rebalanced binocular iPad tablet games (with fellow eye contrast reduced) have been shown to be an effective treatment for amblyopia. However, the games can be challenging for some of the youngest children and boring for some of the older children with amblyopia. To provide additional treatment options using the same contrast-rebalancing approach, we have processed animated videos to allow dichoptic viewing, with full contrast for the amblyopic eye and reduced contrast for the fellow eye. Children will be randomly assigned to watch dichoptic videos (experimental treatment) or patch 2 hours/day every day(standard-of-care amblyopia treatment) for 2 weeks. At the 2-week primary outcome visit, children in the patching group will cross over to the videos and return for a secondary outcome visit at 4 weeks. Families will have the option to continue with the vdeos for up to 8 weeks.

Conditions

• Amblyopia

Interventions

Type	Name	Description
OTHER	patching	covering the fellow eye with an eyepatch to force use of the amblyopic eye
OTHER	Dichoptic videos	watching contrast-rebalanced dichoptic videos to allow the two eyes to work together

Timeline

• Start date: 2019-01-31
• Primary completion: 2021-07-06
• Completion: 2021-08-31
• First posted: 2019-01-31
• Last updated: 2025-01-24

Locations

1 site across 1 country: United States