| Recruiting | National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion o Inherited Ophthalmic Diseases, Hypopigmentation Disorder, Corneal Dystrophy | — | 2024-07-12 |
| Recruiting | Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease Cone-Rod Degeneration, Rod-Cone Degeneration | Phase 1 | 2023-07-25 |
| Completed | Potential Environmental Causes of Uveal Coloboma Coloboma | — | 2023-06-20 |
| Active Not Recruiting | Training to Modify Fixational Eye Movements for Optimizing Visual Performance in People With Central Vision Lo Central Vision Loss From Macular Diseases | N/A | 2022-06-01 |
| Recruiting | Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4 Stargardt-Like Macular Dystrophy | — | 2022-04-19 |
| Withdrawn | Microbiome as a ThErapeutic Response Biomarker Uveitis | — | 2021-05-03 |
| Terminated | Ocular Findings and Viral Persistence in Ocular Fluids in COVID-19 Survivors COVID-19 | — | 2021-02-02 |
| Completed | Biomarkers in Ocular Inflammation and Uveitis Uveitis, Ocular Inflammation | — | 2020-12-29 |
| Recruiting | Oral Metformin for Treatment of ABCA4 Retinopathy ABCA4 Retinopathy, Stargardt Disease, Retinal Dystrophy | Phase 1 / Phase 2 | 2020-11-23 |
| Recruiting | Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Dry Age-Related Macular Degeneration, Geographic Atrophy | Phase 1 / Phase 2 | 2020-09-23 |
| Active Not Recruiting | Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma Retinal Hemangioblastoma, Von Hippel-Lindau Disease | — | 2020-07-02 |
| Completed | Retinitis Pigmentosa Clinical Measures and Repeatability Testing of Potential Outcome Measures Retinitis Pigmentosa | — | 2019-09-27 |
| Recruiting | Perception, Sensation, Cognition and Action in Humans Normal Physiology | — | 2019-03-26 |
| Completed | Generation of Induced Pluripotent Stem (iPS) Cell Lines From Skin Fibroblast Cells of Participants With Age-Re AMD | — | 2018-05-23 |
| Completed | Age-Related Eye Disease Study 2 (AREDS2) 10-year Follow-On AMD, Cancer, Cataract | — | 2018-05-23 |
| Completed | Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation Reticular Pseudodrusen (RPD), Age-Related Macular Degeneration | EARLY_Phase 1 | 2018-05-14 |
| Completed | Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pse AMD | EARLY_Phase 1 | 2018-04-20 |
| Completed | AMD Ryan Initiative Study (ARIS) Age-Related Macular Degeneration | — | 2018-02-12 |
| Completed | Mothers Experiences With X-linked Retinoschisis Compared to Fathers Experiences Retinoschisis, X-Linked | — | 2017-12-01 |
| Completed | PREVAIL VII: Cataract Surgery in Ebola Survivors Cataract | N/A | 2017-09-21 |
| Active Not Recruiting | Dark Adaptation in Participants With Age-Related Macular Degeneration Age-Related Macular Degeneration | — | 2017-06-16 |
| Completed | Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study) Uveitis | Phase 2 | 2017-03-30 |
| Completed | Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration Age-Related Macular Degeneration | — | 2017-03-08 |
| Completed | A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination Von Hippel-Lindau Syndrome | Phase 1 / Phase 2 | 2017-01-23 |
| Completed | Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Dege Age-Related Macular Degeneration | Phase 2 | 2016-12-14 |
| Recruiting | Clinical and Molecular Studies in Families With Inherited Eye Disease Inherited Eye Disease | — | 2016-10-04 |
| Recruiting | Natural History, Pathogenesis, and Outcome of Ocular Disorders Eye Disease | — | 2016-08-03 |
| Completed | Uveitis/Intraocular Inflammatory Disease Biobank (iBank) Uveitis | — | 2016-07-26 |
| Recruiting | Natural History of Spinocerebellar Ataxia Type 7 (SCA7) Spinocerebellar Ataxia | — | 2016-07-11 |
| Recruiting | Rod and Cone Mediated Function in Retinal Disease Retinal Degeneration, Retinitis Pigmentosa, Stargardt's Disease | — | 2016-03-24 |
| Recruiting | Genetics of Inherited Eye Disease Genetic Eye Disease | — | 2015-06-22 |
| Recruiting | Adaptive Optics Retinal Imaging Eye Diseases, Healthy Volunteers | — | 2015-02-20 |
| Completed | The Focal Electro-Oculogram in Macular Disease Macular Degeneration, Age-Related Macular Degeneration | — | 2015-02-06 |
| Terminated | Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy Inherited Ophthalmic Diseases, Inherited Retinal Degeneration | Phase 1 / Phase 2 | 2015-01-14 |
| Completed | People s Expectations When Enrolling in a Phase I/II RS1 Ocular Gene Transfer Clinical Trial Retinoschisis, X-Linked | — | 2014-12-13 |
| Terminated | Study of Retinal Findings in People With Signs and Symptoms of Alzheimer s Disease Enrolled in 09-M-0198 Age-Related Macular Degeneration, Alzheiner's Disease, AMD | — | 2014-08-13 |
| Recruiting | Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions Genetic Eye Disease | — | 2014-08-05 |
| Completed | Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa Retinitis Pigmentosa | Phase 1 / Phase 2 | 2014-05-01 |
| Terminated | A Randomized, Controlled, Double-Masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chroni Graft vs Host Disease | Phase 2 | 2013-11-01 |
| Completed | Intestinal Bacteria and Ocular Inflammatory Disease Uveitis | — | 2013-08-27 |
| Completed | Study of the Effects of Supplements on Eye Disease in Participants From the Age-Related Eye Disease Study AMD, Age- Related Macular Degeneration | — | 2013-07-16 |
| Completed | Color Vision as a Measure for Inherited Retinal Diseases Healthy Volunteer, Retinal Disease, Inherited Retinal Degeneration | — | 2013-06-03 |
| Completed | Nitisinone for Type 1B Oculocutaneous Albinism Albinism, Vision Loss | Phase 1 / Phase 2 | 2013-04-16 |
| Completed | Gevokizumab for Active Scleritis Scleritis | Phase 1 / Phase 2 | 2013-03-01 |
| Recruiting | Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC) Coloboma, Anophthalmia, Microphthalmia | — | 2013-01-08 |
| Completed | AMD Phenotype and Genotype Study Age-Related Macular Degeneration, AMD | — | 2012-11-05 |
| Active Not Recruiting | Natural History of Eye Diseases Related to ABCA4 Mutations Retinal Degeneration, ABCA4-Related Retinopathies | — | 2012-10-09 |
| Withdrawn | Ustekinumab for Active Sight-Threatening Uveitis Uveitis | Phase 1 / Phase 2 | 2012-07-03 |
| Completed | CNTF Implants for CNGB3 Achromatopsia Eye Disease, Achromatopsia | Phase 1 / Phase 2 | 2012-07-01 |
| Recruiting | National Eye Institute Biorepository for Retinal Diseases Age-Related Macular Degeneration, Diabetic Retinopathy, Von Hippel-Lindau Syndrome | — | 2012-06-18 |
| Completed | Ranibizumab and Bevacizumab for Diabetic Macular Edema Diabetic Macular Edema | Phase 2 | 2012-05-01 |
| Terminated | Finasteride for Chronic Central Serous Chorioretinopathy Retinal Disease | Phase 2 | 2012-04-01 |
| Completed | Minocycline to Treat Branch Retinal Vein Occlusion Retinal Vein Occlusion | Phase 1 / Phase 2 | 2012-03-28 |
| Completed | Blood and Saliva Sample Collection for AREDS 2 Age-Related Macular Degeneration, Eye Diseases | — | 2012-02-24 |
| Terminated | Intravitreal Injections of Sirolimus in the Treatment of Geographic Atrophy Geographic Atrophy | Phase 2 | 2012-02-01 |
| Completed | Sirolimus Injections for Autoimmune Scleritis Scleritis | Phase 1 / Phase 2 | 2012-01-01 |
| Completed | Minocycline to Treat Central Retinal Vein Occlusion Retinal Vein Occlusion | Phase 1 / Phase 2 | 2011-12-21 |
| Completed | Topical Interferon Gamma-1b for Central Serous Chorioretinopathy Retinal Disease, Macular Disease | Phase 1 / Phase 2 | 2011-10-01 |
| Recruiting | Cell Collection to Study Eye Diseases Retinal Disease, AMD, Retinal Degeneration | — | 2011-09-07 |
| Completed | Sirolimus for Advanced Age-Related Macular Degeneration Age-Related Macular Degeneration, Geographic Atrophy | Phase 1 / Phase 2 | 2011-09-01 |
| Completed | Dextromethorphan for Diabetic Macular Edema Diabetic Macular Edema | Phase 1 / Phase 2 | 2011-08-01 |
| Completed | Topical Interferon Gamma for Macular Edema Secondary to Uveitis Anterior Uveitis, Uveitis | Phase 1 / Phase 2 | 2011-06-01 |
| Completed | The Natural History of Graft-Versus-Host Disease in the Eyes Graft-Versus-Host Disease | — | 2011-05-20 |
| Active Not Recruiting | Study of Dark Adaptation in Age-Related Macular Degeneration Age-Related Macular Degeneration | — | 2011-05-16 |
| Terminated | Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Meth Non-infectious Intermediate and Posterior Uveitis | Phase 1 / Phase 2 | 2011-02-01 |
| Completed | Palomid 529 in Patients With Neovascular Age-Related Macular Degeneration Age-Related Macular Degeneration | Phase 1 | 2010-12-20 |
| Completed | Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy Retinal Disease | Phase 1 / Phase 2 | 2010-10-01 |
| Recruiting | Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Ge Genotype, Retinal Disease | — | 2010-08-23 |
| Completed | Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis Uveitis | Phase 1 / Phase 2 | 2010-08-01 |
| Terminated | Evaluation of Single Nucleotide Polymorphisms (SNPs) in Patients With and Without Diabetic Macular Edema Diabetic Retinopathy, Diabetic Macular Edema | — | 2010-07-07 |
| Terminated | Immunogenetic Mechanisms in Behcet's Disease Behcet's Disease, Uveitis | — | 2010-04-15 |
| Completed | A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Diabetic Macular Diabetic Macular Edema | Phase 1 / Phase 2 | 2010-04-01 |
| Completed | Rituximab for Autoimmune Retinopathy Autoimmune Disease | Phase 1 | 2010-01-22 |
| Terminated | Internal Monitoring of Eye Movement in Schizophrenia Schizophrenia | — | 2009-11-02 |
| Completed | The Treatment of Uveitic Cystoid Macular Edema With Topical Interferon Gamma Uveitis | Phase 1 | 2009-07-17 |
| Completed | Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior Uveiti Anterior Uveitis | Phase 1 | 2009-04-01 |
| Completed | Pilot Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy Retinal Disease | Phase 1 / Phase 2 | 2009-02-01 |
| Completed | Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AM Age-Related Macular Degeneration | Phase 1 / Phase 2 | 2008-10-01 |
| Recruiting | Screening for Research Participants Eye Diseases | — | 2008-08-20 |
| Completed | Sirolimus to Treat Diabetic Macular Edema Diabetic Retinopathy | Phase 1 / Phase 2 | 2008-07-01 |
| Completed | Evaluation and Treatment of People With Eye Diseases Eye Diseases | — | 2008-06-25 |
| Active Not Recruiting | Age-Related Eye Disease Study (AREDS) Follow-Up Age-Related Macular Degeneration, Cataract | — | 2008-06-02 |
| Completed | Ranibizumab Injections to Treat Macular Telangiectasia With New Blood Vessel Growth Neovascularization | Phase 1 | 2008-05-21 |
| Completed | Ranibizumab Injections to Treat Macular Telangiectasia Without New Blood Vessel Growth Macular Telangiectasia | Phase 1 | 2008-05-21 |
| Completed | Validation of Computerized Vision-Targeted Quality-of-Life Questionnaires Eye Disease | — | 2008-05-09 |
| Terminated | Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau Syndrome Von Hippel-Lindau Syndrome | Phase 1 / Phase 2 | 2008-05-01 |
| Completed | High Speed Indocyanine Green Angiography Findings in Ranibizumab Treatment for Wet Age-related Macular Degener Macular Degeneration | — | 2008-04-07 |
| Completed | Genetics and Markers of Degenerative and Inflammatory Eye Diseases Diabetic Retinopathy, Age-Related Macular Degeneration (AMD), Uveitis | — | 2008-03-27 |
| Completed | Detection of Neutralizing Antibodies in Patients Treated With Bevacizumab or Ranibizumab Macular Degeneration | — | 2008-01-16 |
| Terminated | Visual Motor Coordination Healthy Volunteer, Neurodegenerative Diseases | — | 2007-12-04 |
| Completed | Potential Research Participants for Future Studies of Inherited Eye Diseases Cataract, Glaucoma, Retinitis Pigmentosa | — | 2007-11-09 |
| Terminated | Human Samples and Data Repository Uveitis, Scleritis | — | 2007-08-29 |
| Completed | Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure Turner Syndrome, Ovarian Failure, Premature, Sex Chromosome Aberrations | — | 2007-05-07 |
| Completed | Injected Ranibizumab to Treat Macular Telangiectasia Without New Blood Vessel Formation Telangiectasia | Phase 1 | 2007-03-27 |
| Completed | Injected Ranibizumab to Treat Macular Telangiectasia With New Blood Vessel Formation Telangiectasia | Phase 1 | 2007-03-27 |
| Completed | The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease Uveitis, Vasculitis, Ocular Inflammatory Disease | — | 2007-02-14 |
| Terminated | TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degeneration Age-Related Macular Degeneration | Phase 2 | 2007-01-01 |
| Completed | Longitudinal Evaluation of Silicone Hydrogel (LASH) Study Corneal Infiltrates | — | 2006-10-01 |
| Completed | Metabolic Mapping to Measure Retinal Metabolism Macular Degeneration, Diabetic Retinopathy, Hippel-Landau Disease | Phase 2 | 2006-09-29 |
| Completed | Repository for Inherited Eye Diseases Retinitis Pigmentosa, Inherited Ophthalmic Diseases | — | 2006-09-20 |
| Completed | Eye and Immunogenetic Features of Sarcoidosis Sarcoidosis, Uveitis | — | 2006-09-18 |
| Completed | Age-Related Eye Disease Study 2 (AREDS2) Age-related Macular Degeneration, Cataract | Phase 3 | 2006-09-01 |
| Terminated | Family Studies of Uveal Coloboma Coloboma | — | 2006-07-28 |
| Completed | Vascular Remodeling and the Effects of Angiogenic Inhibition in Diabetic Retinopathy Diabetic Retinopathy | EARLY_Phase 1 | 2006-07-01 |
| Unknown | Tailored Messages to Increase Eye Examination Behavior Eye Disease, Eye Care | N/A | 2006-06-01 |
| Completed | Combination Daclizumab/Denileukin Diftitox to Treat Uveitis Non-infectious Intermediate and Posterior Uveitis | Phase 2 | 2006-05-11 |
| Unknown | 30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers Herpes Simplex | Phase 1 | 2006-04-01 |
| Completed | Dynamic Light Scattering to Study Crystalline Proteins in Young Normal Lenses Healthy | — | 2006-03-15 |
| Completed | Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degeneration Age-Related Macular Degeneration, Choroidal Neovascularization | Phase 2 | 2006-02-01 |
| Completed | Efalizumab to Treat Uveitis Uveitis, Macular Edema | Phase 1 | 2006-01-01 |
| Completed | Clinical and Molecular Studies in Families With Glaucoma and Related Diseases Glaucoma | — | 2005-12-29 |
| Completed | Clinical and Genetic Studies in Families With Myopia and Related Diseases Myopia | — | 2005-12-21 |
| Completed | Correlation of Gene Abnormalities and Clinical Manifestations of Aniridia Aniridia | — | 2005-12-07 |
| Completed | Molecular Genetics of Retinal Degenerations Retinal Degeneration, Retinitis Pigmentosa | — | 2005-09-26 |
| Completed | Triamcinolone Acetonide Injections to Treat Diabetic Macular Edema Diabetic Retinopathy | Phase 2 | 2005-09-01 |
| Completed | Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis Anterior Uveitis, Arthritis, Juvenile Idiopathic, Iritis | Phase 2 | 2005-08-01 |
| Completed | Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60 Macular Degeneration | Phase 1 | 2005-07-14 |
| Unknown | Convergence Insufficiency Treatment Trial (CITT) Convergence Insufficiency, Binocular Vision Disorder | Phase 3 | 2005-07-01 |
| Completed | Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Uveitis, Cancer, Infection | — | 2005-06-16 |
| Completed | Natural History and Genetic Studies of Usher Syndrome Retinitis Pigmentosa Syndromic, Congenital Deafness, Usher Syndrome | — | 2005-03-21 |
| Completed | Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy Exudatiaon, Avascular Retina, Retina Fold | — | 2005-03-18 |
| Completed | Treatment of Diabetic Macular Edema: Triamcinolone Injections Vs. Laser Photocoagulation Diabetic Retinopathy, Diabetic Macular Edema, DME | Phase 3 | 2005-03-09 |
| Completed | Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockage Retinal Vein Occlusion, Macular Edema, Cystoid, Macular Edema | Phase 3 | 2005-03-01 |
| Completed | Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders Macular Degeneration, Retinal Vein Occlusion, Diabetic Retinopathy | Phase 1 | 2005-01-05 |
| Completed | Triamcinolone Acetonide Plus Laser Therapy to Treat Age-Related Macular Degeneration Macular Degeneration | Phase 3 | 2004-12-09 |
| Completed | Visual Cortex Stimulation in Patients With Amblyopia Amblyopia, Anisometropic Ambyopia, Amblyopia, Suppression | Phase 1 | 2004-11-01 |
| Completed | Cyclosporine Implant for Ocular Graft-Versus-Host Disease Graft Vs Host Disease | Phase 1 | 2004-10-14 |
| Completed | Effects of Antioxidants on Human Macular Pigments Eye Health | N/A | 2004-09-01 |
| Completed | Ranibizumab Injections to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome Von Hippel-Lindau Syndrome | Phase 1 | 2004-08-10 |
| Completed | Immune Indicators of Uveitis GITR, GITR Ligand, Uveitis | — | 2004-08-09 |
| Completed | Screening for Research Subjects With Anterior Segment Diseases Eye Diseases | — | 2004-07-13 |
| Completed | Efficacy of Elevated CD4 Counts on CMV Retinitis Acquired Immunodeficiency Syndrome, Cytomegalovirus Retinitis | — | 2004-07-01 |
| Completed | Helicobacter Pylori and Dry Eye Helicobacter Infections | — | 2004-05-01 |
| Completed | Evaluation and Treatment of Eye Complications of Vaccinia Vaccination Vaccinia | Phase 2 | 2004-04-19 |
| Completed | Dynamic Light Scattering for Studying Lens Aging and Cataract Formation Cataract | — | 2004-04-01 |
| Completed | Daclizumab and Sirolimus to Treat Uveitis Uveitis | Phase 1 | 2004-03-03 |
| Completed | Evaluation of the Age-Related Eye Disease Study (AREDS) Clinical Lens Grading System Cataract | — | 2004-02-01 |
| Completed | Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases Eye Diseases | — | 2004-01-14 |
| Completed | Infliximab to Treat Non-Infectious Scleritis Scleritis | Phase 1 | 2003-12-23 |
| Completed | Digital Photography to Evaluate Dry Eye Eye Disease | — | 2003-11-14 |
| Completed | Eye Injections of Triamcinolone Acetonide for Retinal Blood Vessel Disorders Macular Degeneration, Retinal Vein Occlusion | Phase 1 | 2003-10-15 |
| Completed | Daclizumab to Treat Non-Infectious Sight-Threatening Uveitis Uveitis | Phase 2 | 2003-10-06 |
| Completed | Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases Corneal Dystrophies, Hereditary, Corneal Disease | — | 2003-10-06 |
| Completed | Pilot Study of Laser Photocoagulation Therapy for Diabetic Macular Edema Diabetic Retinopathy | Phase 1 | 2003-09-10 |
| Completed | Optical Coherence Tomography Comparative Study Retinal Disease, Healthy | — | 2003-09-01 |
| Completed | Pilot Study: Dynamic Light Scattering Device for Studying Early Changes in Cataract Cataract | — | 2003-08-15 |
| Completed | Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa Retinitis Pigmentosa | Phase 1 | 2003-07-17 |
| Completed | Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin A Retinitis Pigmentosa | Phase 3 | 2003-07-01 |
| Completed | Analyses of Existing Framingham Data Eye Diseases | — | 2003-06-25 |
| Completed | Investigating Age-Related Macular Degeneration Age-Related Macular Degeneration | — | 2003-06-20 |
| Completed | Evaluation of Safety of Ciliary Neurotrophic Factor Implants in the Eye Retinitis Pigmentosa | Phase 1 | 2003-06-01 |
| Active Not Recruiting | Clinical and Genetic Studies of X-Linked Juvenile Retinoschisis Retinoschisis | — | 2003-05-19 |
| Completed | Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Degeneration | Phase 1 | 2003-05-05 |
| Completed | Raman Scattering Spectroscopy to Measure Macular Pigment Raman Spectroscopy | Phase 1 | 2003-05-01 |
| Completed | Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases Eye Diseases | — | 2003-04-07 |
| Terminated | Genetic Factors in Age-Related Macular Degeneration Macular Degeneration | — | 2003-04-04 |
| Completed | Clinical and Genetic Studies of Families With Congenital or Hereditary Cataracts Cataract | — | 2003-03-18 |
| Completed | EYE001 to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome Hippel-Lindau Disease | Phase 1 | 2003-03-01 |
| Completed | Laser and Antioxidant Treatment of Diabetic Macular Edema Macular Edema, Diabetes Mellitus | Phase 1 | 2003-02-01 |
| Completed | Biological Markers in Retinal Vasculitis Retinal Vasculitis | — | 2002-12-06 |
| Completed | Laser and Medical Treatment of Diabetic Macular Edema Macular Degeneration | Phase 3 | 2002-12-01 |
| Completed | Dynamic Light Scattering and Keratoscopy for Corneal Examination Corneal Diseases | — | 2002-12-01 |
| Completed | Saccadic Eye Movements in Patients With Niemann-Pick Type C Disease Niemann Pick Diseases | Phase 1 | 2002-10-17 |
| Completed | Celecoxib to Treat Macular Degeneration in Patients Receiving Photodynamic Therapy Macular Degeneration | Phase 2 | 2002-08-01 |
| Completed | Daclizumab Injections to Treat Non-Infectious Sight-Threatening Uveitis Uveitis | Phase 2 | 2002-08-01 |
| Completed | Prevalence and Risk of Cataracts in Granulocyte Donors Apheresis | — | 2002-07-30 |
| Completed | Differences in Genes and Proteins in Active and Controlled Uveitis Ocular Inflammatory Disease, Uveitis | — | 2002-02-01 |
| Completed | Laser and Medical Treatment of Diabetic Macular Edema Diabetes Mellitus, Macular Edema | Phase 1 | 2001-11-01 |
| Unknown | The Early Treatment for Retinopathy of Prematurity Study (ETROP) Retinopathy of Prematurity | Phase 2 / Phase 3 | 2001-10-01 |
| Completed | Vitamin E to Treat Uveitis-Associated Macular Edema Cystoid Macular Edema, Uveitis | Phase 1 | 2001-07-01 |
| Completed | Identification and Treatment of Feeder Vessels in Macular Degeneration Macular Degeneration | Phase 1 | 2001-06-28 |
| Completed | A Novel Acuity Testing Method Vision Disorder | — | 2001-03-01 |
| Completed | Evaluation and Treatment of Patients With Inherited Eye Diseases Hereditary Eye Disease | — | 2001-02-21 |
| Completed | Evaluation and Treatment of Patients With Corneal and External Diseases Blepharitis, Conjunctivitis, Corneal Disease | — | 2001-01-02 |
| Completed | Fluocinolone Implant to Treat Macular Degeneration Choroidal Neovascularization, Macular Degeneration | Phase 1 | 2001-01-01 |
| Completed | Dynamic Light Scattering Device (DLS) Study of Age-Related Changes in the Lens and Cataracts Cataract, Healthy | — | 2000-12-01 |
| Completed | Evaluation and Treatment of Pediatric Eye Diseases Ocular Motility Disorder | N/A | 2000-10-01 |
| Completed | Lutein for Age-Related Macular Degeneration Macular Degeneration | Phase 2 | 2000-09-01 |
| Completed | Evaluation and Treatment of Patients With Inflammatory Eye Diseases Choroiditis, Iridocyclitis, Iritis | — | 2000-08-19 |
| Completed | Cause of Pigment Dispersion Syndrome Glaucoma, Healthy, Pigment Dispersion Syndrome | — | 2000-06-01 |
| Completed | Magnetic Resonance Imaging to Study the Normal Eye Cataract, Lens Disease | — | 2000-06-01 |
| Completed | Evaluation and Treatment of Patients With Retinal Disease Retinal Disease | — | 2000-05-31 |
| Completed | Blood Factors and Diabetic Retinopathy Diabetic Retinopathy | — | 2000-05-23 |
| Completed | Genetic Study of Age-Related Macular Degeneration Age-Related Macular Degeneration | — | 2000-04-14 |
| Completed | Cornea Donor Study Corneal Disease, Fuch's Dystrophy, Pseudophakic Corneal Edema | N/A | 2000-01-10 |
| Completed | Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family His Healthy, Strabismus | — | 1999-10-01 |
| Completed | Effect of Pregnancy on Uveitis Postpartum Period, Pregnancy, Uveitis | — | 1999-09-01 |
| Completed | Eye Muscle Surgery to Treat Congenital Nystagmus Nystagmus | Phase 2 | 1999-08-01 |
| Completed | HAT in Eye Complications of Behcet's Disease Behcet's Syndrome, Retinal Disease, Uveitis | Phase 2 | 1999-07-01 |
| Completed | Complications of Age-Related Macular Degeneration Prevention Trial Macular Degeneration | Phase 3 | 1999-05-01 |
| Completed | Amblyopia (Lazy Eye) Treatment Study Amblyopia, Anisometropia, Strabismus | Phase 3 | 1999-05-01 |
| Unknown | The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study Myopia | — | 1999-04-01 |
| Completed | Leflunomide to Treat Uveitis Uveitis | Phase 2 | 1999-03-01 |
| Completed | TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid Arthritis Juvenile Rheumatoid Arthritis, Uveitis | Phase 2 | 1999-02-01 |
| Completed | Screening for Studies on Nystagmus and Strabismus Nystagmus, Strabismus | — | 1999-01-29 |
| Completed | Submacular Surgery Trials (SST) Macular Degeneration, Histoplasmosis | Phase 3 | 1999-01-01 |
| Completed | Vascular Endothelial Growth Factor (VEGF) in Uveitis Macular Edema, Cystoid, Uveitis | — | 1998-08-01 |
| Completed | New Cysteamine Eye Drops Formulation to Treat Corneal Crystals in Cystinosis Cystinosis | Phase 1 | 1998-05-01 |
| Completed | Cyclosporin Implant to Treat Uveitis Eye Disease, Inflammation, Uveitis | Phase 1 | 1998-05-01 |
| Completed | Gene Therapy for Gyrate Atrophy Gyrate Atrophy | Phase 1 | 1998-04-01 |
| Completed | Screening for NEI Clinical Studies Conjunctivitis, Iritis, Keratitis | — | 1998-03-23 |
| Completed | Screening for Studies on Retinovascular Diseases Diabetic Retinopathy, Macular Degeneration, Pathologic Neovascularization | — | 1998-03-06 |
| Completed | Screening for Studies on Inherited Eye Diseases Hereditary Eye Disease | — | 1998-02-25 |
| Completed | Congenital Esotropia Observational Study (CEOS) Esotropia | — | 1997-12-01 |
| Completed | Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops Keratoconjunctivitis Sicca, Sjogren's Syndrome | Phase 2 | 1997-11-01 |
| Completed | Test of QLS Device to Detect Early Cataracts Cataract, Healthy | — | 1997-09-01 |
| Completed | The Safety and Efficacy of Chicken Type II Collagen on Uveitis Associated With Juvenile Rheumatoid Arthritis Arthritis, Juvenile Rheumatoid, Uveitis | Phase 1 | 1997-07-01 |
| Completed | Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular D Choroidal Neovascularization, Macular Degeneration | Phase 1 | 1997-07-01 |
| Completed | Cataract Surgery to Obtain Human Lens Material for the Study of Nuclear Cataracts Cataract | — | 1997-05-01 |
| Completed | Long-Term Follow-Up of Patients Enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS) Diabetic Retinopathy | — | 1997-05-01 |
| Completed | Normal Human Electro-Oculogram Healthy | — | 1997-02-01 |
| Completed | Immune Activity Against CVM Retinitis Acquired Immunodeficiency Syndrome, Cytomegalovirus Retinitis, HIV Infection | — | 1997-02-01 |
| Completed | Studies of Families With Hereditary Cataracts Cataract, Congenital Anomaly | — | 1996-10-01 |
| Completed | ANTI-TAC THERAPY FOR UVEITIS Uveitis | Phase 1 | 1996-06-04 |
| Unknown | A Trial of Bifocals in Myopic Children With Esophoria Myopia, Strabismus, Esophoria | Phase 3 | 1996-06-01 |
| Completed | Intravenous Immunoglobulin Therapy in Optic Neuritis Optic Neuritis | Phase 3 | 1995-08-01 |
| Completed | The Effects of Light Reduction on Retinopathy of Prematurity (Light-ROP) Retinopathy of Prematurity | Phase 3 | 1995-07-01 |
| Unknown | The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Keratoconus | — | 1995-06-01 |
| Completed | Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS) Cataract | Phase 3 | 1995-05-01 |
| Unknown | Ischemic Optic Neuropathy Decompression Trial Followup (IONDT Followup) Ischemic Optic Neuropathy | — | 1994-10-01 |
| Completed | Long Term Follow-Up of Diabetic Retinopathy Blindness, Cataract, Diabetes Mellitus | — | 1994-03-01 |
| Unknown | Safety and Efficacy of a Heparin-Coated Intraocular Lens in Uveitis Cataract, Uveitis | Phase 2 | 1994-03-01 |
| Unknown | Collaborative Initial Glaucoma Treatment Study (CIGTS) Open-Angle Glaucoma | Phase 3 | 1993-10-01 |
| Unknown | Randomized Trials of Vitamin Supplements and Eye Disease Macular Degeneration, Cataract | Phase 3 | 1993-08-01 |
| Completed | Study of Usher Syndromes, Type 1 and Type 2 Retinitis Pigmentosa | — | 1993-06-01 |
| Completed | Diabetic Retinopathy and Visual Function Study Diabetic Retinopathy, Macular Degeneration, Vision, Subnormal | — | 1992-11-01 |
| Completed | Ischemic Optic Neuropathy Decompression Trial (IONDT) Ischemic Optic Neuropathy | Phase 3 | 1992-10-01 |
| Completed | Ganciclovir Implant Study for Cytomegalovirus Retinitis HIV Infections, Acquired Immunodeficiency Syndrome, Cytomegalovirus Retinitis | Phase 3 | 1992-10-01 |
| Unknown | Early Manifest Glaucoma Trial (EMGT) Open-Angle Glaucoma | Phase 3 | 1992-10-01 |
| Completed | Herpetic Eye Disease Study (HEDS) II Keratitis, Herpetic, Ocular Herpes Simplex, Herpes Simplex | Phase 3 | 1992-10-01 |
| Completed | Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients Cataracts | Phase 2 | 1992-04-01 |
| Terminated | Tissue Studies of Human Eye Diseases Retinal Disease, Corneal Disease, Diabetic Retinopathy | — | 1992-03-05 |
| Completed | Study of Eye Tissue for Sarcoidosis Sarcoidosis | — | 1991-05-01 |
| Completed | Randomized Trial of Acetazolamide for Uveitis-Associated Cystoid Macular Edema Macular Edema, Cystoid | Phase 2 | 1990-12-01 |
| Completed | Age-Related Eye Disease Study (AREDS) Macular Degeneration, Cataract, Lens Opacities | Phase 3 | 1990-09-01 |
| Completed | Endophthalmitis Vitrectomy Study (EVS) Endophthalmitis, Eye Infections | Phase 3 | 1990-02-01 |
| Unknown | Herpetic Eye Disease Study (HEDS) I Keratitis, Herpetic, Ocular Herpes Simplex | Phase 3 | 1989-05-01 |
| Completed | Central Vein Occlusion Study (CVOS) Retinal Vein Occlusion, Retinal Diseases | Phase 3 | 1988-08-01 |
| Unknown | Longitudinal Optic Neuritis Study (LONS) Multiple Sclerosis, Optic Neuritis | N/A | 1988-07-01 |
| Unknown | Optic Neuritis Treatment Trial (ONTT) Multiple Sclerosis, Optic Neuritis | Phase 3 | 1988-07-01 |
| Unknown | Advanced Glaucoma Intervention Study (AGIS) Glaucoma | Phase 3 | 1988-04-01 |
| Completed | Analysis of Eye Tissue Eye Disease, Inflammation, Uveitis | — | 1987-07-01 |
| Unknown | Collaborative Ocular Melanoma Study (COMS) Choroid Neoplasms, Uveitis | Phase 3 | 1986-11-01 |
| Completed | Collaborative Corneal Transplantation Studies (CCTS) Corneal Transplantation, Graft Rejection | Phase 3 | 1986-05-01 |
| Completed | Cysteamine Eye Drops to Treat Corneal Crystals in Cystinosis Cystinosis | Phase 2 | 1986-04-01 |
| Completed | Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Premat Retinopathy of Prematurity | N/A | 1986-01-01 |
| Completed | The Silicone Study Proliferative Vitreoretinopathy, Retinal Detachment | Phase 3 | 1985-09-01 |
| Completed | Fluorouracil Filtering Surgery Study (FFSS) Glaucoma | Phase 3 | 1985-09-01 |
| Completed | Clinical Trial of Eye Prophylaxis in the Newborn Chlamydia Infections, Ophthalmia Neonatorum | Phase 3 | 1985-01-01 |
| Completed | Krypton-Argon Regression of Neovascularization Study (KARNS) Diabetic Retinopathy, Retinal Neovascularization, Diabetes Mellitus | Phase 3 | 1984-12-01 |
| Completed | Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa Retinitis Pigmentosa | Phase 3 | 1984-05-01 |
| Completed | The Prism Adaptation Study (PAS) Esotropia | Phase 3 | 1984-03-01 |
| Completed | Glaucoma Laser Trial (GLT) Glaucoma Laser Trial Followup Study (GLTFS) Open-Angle Glaucoma | Phase 3 | 1984-01-01 |
| Completed | Sorbinil Retinopathy Trial (SRT) Diabetic Retinopathy, Diabetes Mellitus | Phase 3 | 1983-08-01 |
| Terminated | Randomized Trial of Aspirin and Cataracts in U.S. Physicians Cataract | Phase 3 | 1982-04-01 |
| Unknown | Randomized Trial of Beta-Carotene and Macular Degeneration Macular Degeneration | Phase 3 | 1982-04-01 |
| Completed | Prospective Evaluation of Radial Keratotomy (PERK) Study Myopia | Phase 3 | 1981-04-01 |
| Completed | Visual Stimulus and Eye Movement Healthy | — | 1980-08-26 |
| Completed | Early Treatment Diabetic Retinopathy Study (ETDRS) Blindness, Diabetic Retinopathy | Phase 3 | 1979-12-01 |
| Unknown | Macular Photocoagulation Study (MPS) Choroidal Neovascularization, Macular Degeneration, Histoplasmosis | Phase 3 | 1979-02-01 |
| Completed | The Berkeley Orthokeratology Study Astigmatism, Myopia | Phase 3 | 1978-01-01 |
| Completed | Gyrate Atrophy of the Choroid and Retina Gyrate Atrophy | — | 1978-01-01 |
| Completed | Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens Aniridia, Eye Abnormality, Ocular Hypertension | — | 1977-07-01 |
| Completed | Branch Vein Occlusion Study Macular Degeneration, Neovascularization, Pathologic, Vitreous Hemorrhage | Phase 3 | 1977-07-01 |
| Completed | Diabetic Retinopathy Vitrectomy Study (DRVS) Diabetic Retinopathy, Retinal Detachment, Vitreous Hemorrhage | Phase 3 | 1976-10-01 |
| Completed | Visual Function and Ocular Pigmentation in Albinism Albinism, Albinism, Ocular, Albinism, Oculocutaneous | — | 1976-06-01 |
| Completed | Pigment Dispersion Syndrome With and Without Glaucoma Glaucoma, Glaucoma, Open-Angle, Ocular Hypertension | — | 1976-06-01 |
| Completed | Diabetic Retinopathy Study (DRS) Diabetic Retinopathy, Blindness | Phase 3 | 1972-01-01 |
| Unknown | Vision In Preschoolers Study (VIP Study) Amblyopia, Strabismus, Refractive Error | Phase 3 | — |
| Completed | The Contact Lens and Myopia Progression (CLAMP) Study Myopia | — | — |
| Unknown | The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated With Juvenile Uveitis, Arthritis, Juvenile Rheumatoid | Phase 3 | — |