NCT07437807

Vision Therapy Outcomes in Amblyopia: Linking Brain Plasticity With Visual Perceptual Skills

Correlation of Vision Therapy With Visual-Cognitive Skills and Therapeutic Outcomes in Amblyopia: Linking Brain Plasticity With Visual Perceptual Skills

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 38 (actual)
• Sponsor: Okan University · Academic / Other
• Sex: All
• Age: 4 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study is to evaluate the effects of a personalized vision therapy programme tailored to baseline visual-cognitive abilities in treatment-resistant amblyopia. In addition to testing the hypothesis that rehabilitation protocols targeting amblyopia related visual-perceptual and visual-cognitive skills. Spesific aims of this study are: 1. to identify which visual perceptual skills are most significantly impaired sen patients with amblyopia. 2. to evaluate whether interventions are targeting fundamental visual perceptual skills are associated with improvements in higher-order visual perceptual skills. 3. to determine whether vision therapy tailored to individual neuro-visual impairments associated with improvements in binocular function, including streopsis and overall visual perceptual performance. 4. to ases whether baseline neuro-visual perceptual performance predicts the response to vision therapy in patients with amblyopia.

Conditions

• Amblyopia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Motor Free Perception Vision Test	The Motor-Free Visual Perception Test-3 (MVPT-3) represents a significant methodological iteration in the assessment of non-motor visual processing, specifically validated for individuals ranging from 4 to 95 years of age. In pediatric and adolescent contexts (under 18), the MVPT-3 is utilized to isolate cognitive visual-perceptual skills-such as spatial relationships, visual discrimination, figure-ground, and visual closure-from fine motor coordination, which may still be developing or impaired. The test consists of 65 items arranged in a horizontal format to accommodate individuals with hemispatial neglect or limited field of vision. For younger examinees, the assessment is particularly vital for identifying perceptual deficits that may impede academic performance, such as reading fluency or mathematical reasoning, without the results being skewed by the child's handwriting or drawing abilities. By providing age-adjusted normative data, the MVPT-3 allows clinicians to derive standard

Timeline

• Start date: 2024-06-12
• Primary completion: 2025-06-12
• Completion: 2025-09-30
• First posted: 2026-02-27
• Last updated: 2026-03-10

Locations

1 site across 1 country: Turkey (Türkiye)