NCT03788031

Perceptual Learning Treatment for Amblyopia

Towards Developing a Perceptual Learning Treatment for Amblyopia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: The Hong Kong Polytechnic University · Academic / Other
• Sex: All
• Age: 7 Years
• Healthy volunteers: Accepted

Summary

Objectives. To develop a new treatment for amblyopia using a perceptual learning approach. Hypothesis to be tested. Our proposed experiments are designed to investigate whether practicing a grating detection task can improve vision in patients with amblyopia. Design and subjects. A total of 36 patients with amblyopia will be randomized allocated into two intervention groups: Group 1, perceptual learning therapy. Group 2, occlusion therapy. A control group comprising of 18 subjects with normal vision will be recruited for comparison. A battery of tests will be used to assess a range of visual functions before and after the treatment intervention. Study instruments. Grating acuity testing system Interventions. We have established a clinical protocol for acuity training. On each trial, a properly oriented stimulus will be presented randomly at one of the four locations on a flat monitor screen. The visual task is to indicate the location of the stimulus. Participants will be required to undertake 20 one-hour sessions of training. Main outcome measures. Resolution acuity, visual acuity, contrast sensitivity function

Conditions

• Amblyopia

Interventions

Type	Name	Description
OTHER	Acuity training	The intervention will be a vision therapy. On each trial, a properly oriented stimulus will be presented randomly at one of the four locations on a flat monitor screen. The visual task is to identify the location of the stimulus.
OTHER	Occlusion therapy	Participants will be required to patch the good eye for 20 days, 1 hour per day.

Timeline

• Start date: 2019-03-01
• Primary completion: 2022-12-31
• Completion: 2023-02-28
• First posted: 2018-12-27
• Last updated: 2024-08-29

Locations

1 site across 1 country: Hong Kong