| Not Yet Recruiting | SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver Disease NCT03867487 | Justin Ryder | Phase 2 |
| Not Yet Recruiting | GLP-1 RA on Liver OMICS in MASLD NCT06982378 | Medical College of Wisconsin | — |
| Not Yet Recruiting | RE and Probiotics in MAFLD/NAFLD NCT06563921 | Nicolaus Copernicus University | N/A |
| Recruiting | Accurate Point of Care Liver Disease Diagnostics (Phase 2) NCT07518784 | University of California, San Diego | — |
| Not Yet Recruiting | Chrononutrition/ Chronotoxicity Intervention in People With Metabolic-associated Steatotic Liver Disease. NCT06705868 | Cyprus University of Technology | N/A |
| Not Yet Recruiting | Rutin and Vitamin C in Patients With Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) NCT07310407 | Ain Shams University | Phase 2 |
| Not Yet Recruiting | Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis NCT02933554 | Keith Pereira, MD: | N/A |
| Not Yet Recruiting | The Improvement Effect of Henggliejin on Fatty Liver in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver NCT07198516 | Fujian Medical University Union Hospital | EARLY_Phase 1 |
| Recruiting | Evaluation of a New Ultrasound System for the Non-invasive Assessment of Liver Steatosis in MASLD/MASH Patient NCT06661655 | E-Scopics | N/A |
| Recruiting | The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health NCT07093346 | University of Nottingham | N/A |
| Recruiting | Digoxin In NASH (CODIN) NCT06588699 | Yale University | Phase 2 |
| Enrolling By Invitation | Hepatic Elastography-Enhanced Lifestyle Modification in MASLD NCT06826807 | Mahidol University | N/A |
| Not Yet Recruiting | Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals NCT05842850 | Steno Diabetes Center Copenhagen | N/A |
| Recruiting | Secondary and Tertiary Digital Prevention of Non-alcoholic and Dysmetabolic Liver Disease NCT06879236 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Not Yet Recruiting | Intermittent Fasting, Mediterranean Diet and NAFLD NCT06615817 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Recruiting | Optimizing Noninvasive assessMent Of DysmEtabolic Compensated Advanced Liver Disease NCT06888310 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | Prevalence of Non-Alcoholic Fatty Liver Disease in Inflammatory Bowel Disease Patients NCT06814600 | Centre Hospitalier Universitaire Saint Pierre | — |
| Enrolling By Invitation | The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD. NCT06334666 | Mahidol University | N/A |
| Active Not Recruiting | A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017) NCT06465186 | Merck Sharp & Dohme LLC | Phase 2 |
| Recruiting | Lifestyle Changes in PCOS with OSA and NAFLD NCT06591169 | Cairo University | N/A |
| Recruiting | Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study) NCT05935826 | University of Colorado, Denver | Phase 3 |
| Active Not Recruiting | A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH NCT06410924 | Neuraly, Inc. | Phase 2 |
| Recruiting | Effects of Almonds in Glucose-intolerant Adults (AGAMEMNON) NCT06413069 | Charite University, Berlin, Germany | N/A |
| Recruiting | Vigorous- Versus Moderate-intensity Exercise to Reduce Liver Fat in Adults With Obesity and NAFLD NCT06124456 | The University of Hong Kong | N/A |
| Not Yet Recruiting | Effect of Consumption of Millet Diet in Patients With NAFLD NCT06341790 | Institute of Liver and Biliary Sciences, India | N/A |
| Not Yet Recruiting | AGED Diagnostics Liver Disease Assessment NCT06348563 | Active Genomes Expressed Diagnostics, Corp | EARLY_Phase 1 |
| Completed | Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects W NCT06389851 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Recruiting | Impact of NAFLD vs MAFLD Stigma on Quality of Life in Egyptian Patients NCT06503068 | Tanta University | — |
| Not Yet Recruiting | Preoperative Ketogenic Diet for Reduction of Hepatic Steatosis NCT05884723 | Western University, Canada | N/A |
| Recruiting | Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB) NCT06599918 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 2 |
| Active Not Recruiting | An Imaging-based Quantitative Biomarker Assay for NAFLD in Children NCT06354491 | University of Wisconsin, Madison | N/A |
| Recruiting | Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Pa NCT06275906 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Enrolling By Invitation | Short and Long Term Clinical and Patient-Reported Outcomes Associated With Intragastric Balloon Placement in P NCT07493967 | Methodist Health System | — |
| Recruiting | Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant NCT05424003 | Virginia Commonwealth University | Phase 2 |
| Recruiting | Bicalutamide Therapy in Young Women With NAFLD and PCOS NCT05979389 | University of California, San Francisco | Phase 1 |
| Completed | A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men NCT04186260 | University of Arizona | N/A |
| Recruiting | NAFLD Clinical Care Pathway NCT06671886 | VA Office of Research and Development | N/A |
| Recruiting | Androgens and NAFLD Longitudinal Cohort Study NCT06124261 | University of California, San Francisco | — |
| Unknown | Different Exercise Modalities in the Treatment of NAFLD and Their Impact on Myokines NCT06257732 | Yeditepe University | N/A |
| Recruiting | Evaluate the Efficacy and Safety of LivPhcD Capsules in the NAFLD Subjects NCT05930093 | TCM Biotech International Corp. | N/A |
| Unknown | Prevalence of Non-alcoholic Fatty Liver Disease in Patients With Chronic Kidney Disease in Assiut NCT06009250 | Muhammad Ameen Abdelrady Abdelaziz | — |
| Unknown | Echocardiographic Findings as Markers of Subclinical Cardiac Dysfunction in Patients With Non-Alcoholic Fatty NCT06130202 | Assiut University | — |
| Withdrawn | Assessment of Fatty Liver With Thermo-acoustic Device NCT04302051 | Medical College of Wisconsin | — |
| Not Yet Recruiting | NAFLD in Patient of Hypothyroidism NCT05813301 | Assiut University | — |
| Unknown | Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Ana NCT06060886 | Consorcio Centro de Investigación Biomédica en Red (CIBER) | Phase 4 |
| Recruiting | Effect of CoQ10 on the Outcome of MAFLD Patients NCT05984745 | Ain Shams University | Phase 2 |
| Active Not Recruiting | A Nutrigenetic Intervention in MASLD NCT06220695 | Maastricht University | N/A |
| Recruiting | Deep Phenotyping of Peripheral Blood Cells and Circulating Factors in Metabolic Diseases NCT06396871 | Technische Universität Dresden | — |
| Recruiting | Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD NCT06186869 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Not Yet Recruiting | Relation Between NAFLD and BM DENSITY NCT06038253 | Assiut University | — |
| Active Not Recruiting | Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD NCT04861571 | University of Iowa | N/A |
| Completed | Determination of Biological Activity of Enriched Serum Following TOTUM-448 Consumption NCT06047847 | Valbiotis | N/A |
| Completed | Improving Detection and Evidence-based Care of NAFLD in Latinx and Black Patients With Type 2 Diabetes NCT05844137 | Duke University | N/A |
| Unknown | Exploring the Mechanism of Dietary Pattern Improving MAFLD NCT05960396 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Lifestyle Modification in the Treatment of NAFLD. NCT05816915 | General University Hospital, Prague | N/A |
| Unknown | Risk Factors for Advanced Fibrosis Among FLD Patients NCT05971082 | Helsinki University Central Hospital | — |
| Active Not Recruiting | Effects of Phytosterol Supplementation on Liver Function and Inflammatory Status in Patients with Nonalcoholic NCT06697977 | University of Jordan | N/A |
| Active Not Recruiting | Accurate Point of Care Liver Disease Diagnostics NCT05986916 | University of California, San Diego | — |
| Unknown | A Study to Evaluate the Safety and Effectiveness of Saroglitazar 4 mg in Patients With NAFLD With Comorbiditie NCT05872269 | Zydus Lifesciences Limited | Phase 4 |
| Recruiting | Prospective Cohort and Biobank of Patients With Nonalcoholic Fatty Liver Disease NCT07051863 | Fondazione Epatocentro Ticino | — |
| Recruiting | Cardiac Dysfunction in Patients with Fatty Liver Disease NCT06386094 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Not Yet Recruiting | Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC) NCT05857319 | Groupe Éthique et Santé | — |
| Completed | Effects of Berberine in Reducing Abdominal Visceral Adipose Tissue Among Individuals with Obesity and NAFLD NCT05647915 | China National Center for Cardiovascular Diseases | Phase 4 |
| Completed | Dasatinib and Quercetin to Treat Fibrotic Non-alcoholic Fatty Liver Disease NCT05506488 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 1 / Phase 2 |
| Recruiting | Prevalence of NAFLD in T1DM Patients NCT06445361 | Ziekenhuis Oost-Limburg | N/A |
| Completed | A Feasibility Trial of OCM Supplements for the Treatment of NAFLD NCT05720702 | Duke University | EARLY_Phase 1 |
| Completed | A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6 NCT05877547 | Merck Sharp & Dohme LLC | Phase 2 |
| Unknown | Development and Validation of a Multi-target, Blood-based NAFLD Diagnosis Test NCT05108415 | HBI Solutions Inc. | — |
| Completed | Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects With Chronic Li NCT05669677 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Unknown | Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance i NCT05773183 | Royal College of Surgeons, Ireland | — |
| Recruiting | Target of Suv420h1/2 in Hepatocytes NCT06332677 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Unknown | Phase Ib/II Study to Evaluate the Efficacy and Safety of GH509 Versus Placebo in Patients With NASH/NAFLD NCT05784779 | 1Globe Biomedical Co., Ltd. | Phase 1 / Phase 2 |
| Recruiting | Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC) NCT05781568 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | — |
| Unknown | Effectiveness of Ultrasound in Liver Stiffness and Fat Quantification NCT06111859 | King's College Hospital NHS Trust | N/A |
| Unknown | Nutraceutical Improvement of Glucose Metabolism, NAFLD and Insulin Resistance by Oat-fiber Supplementation in NCT05654805 | Charite University, Berlin, Germany | N/A |
| Unknown | The Acute Effects of Eucaloric and Hypocaloric Carbohydrate Restriction on Liver Fat Content and Metabolism in NCT05643521 | Hvidovre University Hospital | N/A |
| Completed | Can Fecal Calprotectin Be Used as a Biomarker of Non-alcoholic Fatty Liver Disease In Obese Adolescents? NCT06229184 | Sisli Hamidiye Etfal Training and Research Hospital | N/A |
| Terminated | Systems Biology of Gastrointestinal and Related Diseases NCT05579444 | Viome | — |
| Unknown | Efficacy of N-Acetylcysteine in Improving/Normalizing ALT & AST in Patients of NAFLD NCT05576428 | Dow University of Health Sciences | N/A |
| Active Not Recruiting | Dietary Counseling Coupled With FMT in the Treatment of Obesity and NAFLD - the DIFTOB Study NCT05607745 | University of Eastern Finland | N/A |
| Enrolling By Invitation | Semaglutide vs Sitagliptin NCT05195944 | University Health Network, Toronto | Phase 4 |
| Active Not Recruiting | The Effects of Glucagon on Hepatic Metabolism NCT05500586 | Adrian Vella | Phase 1 / Phase 2 |
| Active Not Recruiting | A Study to Evaluate the Efficacy and Safety of Rencofilstat in Subjects With NASH and Advanced Liver Fibrosis NCT05402371 | Hepion Pharmaceuticals, Inc. | Phase 2 |
| Completed | Ketohexokinase Inhibition in NAFLD NCT05463575 | Maastricht University Medical Center | Phase 2 |
| Completed | Web-based Interventions on Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Children NCT05527938 | Shaoxing Maternity and Child Health Care Hospital | N/A |
| Completed | The Effect of Soy Isoflavones on Non-alcoholic Fatty Liver Disease and the Level of FGF-21 and Fetuin A NCT06101433 | Ahvaz Jundishapur University of Medical Sciences | N/A |
| Active Not Recruiting | The Franciscus Obesity NASH Study NCT05499949 | Franciscus Gasthuis | — |
| Recruiting | NASH AMPK Exercise Dosing (AMPED) Trial NCT04987879 | Milton S. Hershey Medical Center | N/A |
| Completed | Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Live NCT05560607 | AstraZeneca | Phase 1 |
| Completed | The Impact of Ibutamoren on Nonalcoholic Fatty Liver Disease NCT05364684 | Massachusetts General Hospital | Phase 2 |
| Completed | Effects of VLCD and Bariatric Surgery in Patients With Type 2 Diabetes NCT05092399 | University of Nottingham | — |
| Terminated | Utilization of MAsS in Patients Undergoing LT for HCC NCT05184283 | Columbia University | — |
| Completed | Healthy Liver - Healthy Brain NCT05216796 | University of Texas at Austin | N/A |
| Active Not Recruiting | Nonalcoholic Fatty Liver Disease in HIV Database NCT05023044 | Johns Hopkins University | — |
| Recruiting | Evaluation of Gut Permeability in Patients Affected by Obesity and NAFLD: Influence of Ketogenic Diet. NCT05477212 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Completed | Different Doses of ZED1227 vs. Placebo in NAFLD NCT05305599 | Dr. Falk Pharma GmbH | Phase 2 |
| Completed | The Visceral Adiposity Measurement and Observation Study NCT05383456 | Theratechnologies | — |
| Recruiting | Comparison of Two sTRAtegies For the Non-Invasive Diagnosis of advanCed Liver Fibrosis in NAFLD NCT04681573 | University Hospital, Angers | N/A |
| Completed | Prevalence of NAFLD in ACS Patients NCT05378321 | Ziekenhuis Oost-Limburg | N/A |
| Active Not Recruiting | Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B Patients NCT05147090 | The University of Hong Kong | Phase 4 |
| Unknown | Weight Loss Effects of M-health App in Obesity Multidisciplinary Outpatient Clinic NCT05168072 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | N/A |
| Unknown | Characterization of the Platelet Inflammatory Response in NAFL and NASH NCT05128253 | Stefania Basili | — |
| Completed | The Effects of Dihydromiricetin on MASLD NCT05052515 | University of Athens | N/A |
| Unknown | Fruit and Vegetable Products Enriched With Fibre From Potato Starch With Prebiotic Properties for Children and NCT05140070 | Children's Memorial Health Institute, Poland | N/A |
| Recruiting | Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With NCT06308757 | University of Bologna | N/A |
| Unknown | Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty NCT04976283 | Getz Pharma | Phase 4 |
| Completed | Postprandial VLDL-triglyceride Metabolism in Type 2 Diabetes Patients With and Without NAFLD NCT05044130 | University of Aarhus | N/A |
| Completed | Probiotic Supplementation IN NAFLD Patients NCT06074094 | Ain Shams University | Phase 4 |
| Completed | Vigabatrin and Insulin Sensitivity NCT04321395 | Washington University School of Medicine | Phase 2 |
| Completed | Effects of Online App Weight Loss Programs on Liver Health in Obese Adults NCT05015491 | Noom Inc. | N/A |
| Unknown | MLCT Oil for Fatty Liver - PASS Trial NCT05217745 | National University Hospital, Singapore | N/A |
| Unknown | Determination of Insulin-stimulated Hepatic Glucose Uptake by PET-CT Measurements NCT04938544 | Maastricht University Medical Center | — |
| Completed | The Effect of Time-restricted Eating on Liver Metabolism NCT04997486 | University of California, Davis | N/A |
| Active Not Recruiting | Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV NCT04795219 | University of California, San Francisco | — |
| Recruiting | Human Liver ORganoids as a Model to Study the Development of Non-Alcoholic SteatOhepatitis (NASH) NCT06856252 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Recruiting | Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) NCT04634643 | Yale University | — |
| Completed | Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus NCT04232293 | Nantes University Hospital | N/A |
| Completed | Low-Calorie Diet in People With Prediabetes/Metabolic Syndrome NCT04786418 | University of Liverpool | N/A |
| Not Yet Recruiting | THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis) NCT04925362 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Bariatric Endoscopy and NAFLD NCT04895943 | University Hospital Ostrava | — |
| Unknown | Characterization of Visceral Adiposity in HIV Mono-infected Patients With NAFLD NCT05359471 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | COVID-19 and Nonalcoholic Fatty Liver Disease NCT04982328 | University Hospital for Infectious Diseases, Croatia | — |
| Terminated | Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease NCT04576923 | Indiana University | N/A |
| Completed | Correlation Between Hepatic Fibrosis and Cardiovascular Risk Evaluated by Non-invasive Tests in Patients With NCT04774302 | Clinique Pasteur | — |
| Completed | DDI Study of ASC41 in HV and the PK, Safety and Tolerability in Subjects With NAFLD. NCT04845646 | Gannex Pharma Co., Ltd. | Phase 1 |
| Unknown | Plant Stanols and Liver Inflammation in Overweight and Obese Children NCT04783116 | Maastricht University Medical Center | N/A |
| Completed | Serum Selenium and Zinc Levels in Non-alcoholic Fatty Liver Disease Patients NCT04834063 | Sohag University | — |
| Unknown | Defining Circadian Metabolism in Non-alcoholic Fatty Liver Disease NCT05962099 | University of Oxford | — |
| Completed | Economic Burden of NAFLD NCT05035043 | Hasselt University | N/A |
| Completed | Chronic Kidney Disease and Non-alcoholic Fatty Liver Diseases NCT04779905 | Sohag University | — |
| Completed | A Phase 1 Study of DD01 in Overweight/Obese Subjects With T2DM and NAFLD NCT04812262 | Neuraly, Inc. | Phase 1 |
| Completed | Quantifying Body Composition and Liver Disease in Children Using Free-Breathing MRI and MRE NCT04591106 | University of California, Los Angeles | — |
| Unknown | An Investigator Initiated Prospective, Four Arms Randomized Comparative Study of Efficacy and Safety of Sarogl NCT04193982 | Asian Institute of Gastroenterology, India | Phase 3 |
| Completed | Efficacy and Safety of Tocovid Suprabio 200mg in Non-alcoholic Fatty Liver (NAFL) NCT04704063 | Yuen Kah Hay | Phase 2 |
| Completed | Study to Evaluate the Effect of Food on the Pharmacokinetics of ASC41 in Healthy Volunteers NCT04692025 | Gannex Pharma Co., Ltd. | Phase 1 |
| Completed | Study to Evaluate the Safety and Efficacy of ASC41 in Overweight and Obese Subjects NCT04686994 | Gannex Pharma Co., Ltd. | Phase 1 |
| Unknown | The Influence of Probiotic Supplementation on Depressive Symptoms, Inflammation and Oxidative Stress Parameter NCT04756544 | Medical University of Lodz | Phase 3 |
| Unknown | Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH NCT04702490 | Metacrine, Inc. | Phase 2 |
| Completed | The Role of Dietary Carbohydrate and Fat Availability in the Regulation of Hepatic Lipid Content NCT04581421 | Hvidovre University Hospital | N/A |
| Completed | Follow-up of NAFLD Patients With MRI-PDFF NCT04910178 | Asmaa Abdelfattah Elsayed | Phase 4 |
| Unknown | NASH in Subjects With Different Classes of Obesity NCT04653103 | Catholic University of the Sacred Heart | — |
| Unknown | Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk NCT05309057 | University of Toronto | — |
| Completed | Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease NCT05768334 | Helwan University | Phase 3 |
| Active Not Recruiting | The MULTISITE Study NCT05699863 | Aalborg University Hospital | N/A |
| Unknown | Bariatric Endoscopy and NAFLD NCT04669470 | University of Ostrava | N/A |
| Unknown | Whey or Casein - Liver Fat Reduction and Metabolic Improvement by Fast vs. Slow Proteins NCT04564391 | Charite University, Berlin, Germany | N/A |
| Unknown | The Availability of the Enhanced Liver Fibrosis (ELF) Test Affects the Rate of Diagnosis of Nonalcoholic Steat NCT05370053 | University of Kansas Medical Center | N/A |
| Unknown | Impact of Exercise Intervention for Patients With Non-alcoholic Fatty Liver Disease NCT04463667 | National Taiwan University Hospital | N/A |
| Completed | Liver Fat as a Dietary Target for Treating Cardiometabolic Disorders in Prediabetes and Type 2 Diabetes NCT04527965 | Uppsala University | N/A |
| Unknown | Hyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease NCT06176079 | Michael Ohliger, MD PhD | — |
| Unknown | Study Visceral Adipose Tissue and Liver Stifness in a Retrospective Cohort of Diabetes Mellitus Patients NCT04493814 | Central Hospital, Nancy, France | — |
| Recruiting | The Liver BIoBank Lombardia of Fatty Liver NCT06566105 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Unknown | T1-mapping by Cardiovascular Magnetic Resonance Imaging to Assess Non-Alcoholic Fatty Liver Disease NCT04220450 | Dr. Andreas Kammerlander | — |
| Recruiting | Effectiveness of Bariatric Surgery for NAFLD/NASH NCT04366999 | Beijing Friendship Hospital | — |
| Unknown | Safety and Tolerability of Novel Medical Nutrition Products for NAFLD Treatment NCT04308980 | Russian Academy of Medical Sciences | Phase 2 / Phase 3 |
| Completed | Study of NGM395 in Adult Participants NCT04187339 | NGM Biopharmaceuticals, Inc | Phase 1 |
| Unknown | NASH and Type 2 Diabetes: Role of the Receptor Activator of Nuclear Factor-κB (RANK) and Its Ligand (RANKL) NCT03968354 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Adipokine Genetic Variations in predictingNAFLD Progression to NASH in Egyptian Patients NCT04561895 | Cairo University | — |
| Unknown | The Effect of Consecutive Fecal Microbiota Transplantation on Non-Alcoholic Fatty Liver Disease (NAFLD) NCT04465032 | Leiden University Medical Center | Phase 4 |
| Completed | Screening in Primary Care of Advanced Liver Fibrosis in NAFLD and/or Alcoholic Patients (IMPROVE Study) NCT04146636 | University Hospital, Angers | N/A |
| Unknown | NAFLD in HIV-infected Patients NCT04215926 | Shanghai Public Health Clinical Center | — |
| Unknown | The Role of Bariatric Surgeries in Management of Nonalcoholic Fatty Liver Disease NCT04127370 | Assiut University | N/A |
| Completed | EUS Guided Liver Biopsy - Will it Give Better Yield, More Tissue With Less Complication? NCT04235855 | Asian Institute of Gastroenterology, India | N/A |
| Terminated | Vitamin E for NASH Treatment in HIV Infected Individuals NCT03669133 | Indiana University School of Medicine | Phase 2 |
| Active Not Recruiting | LITMUS Imaging Study NCT05479721 | University of Oxford | — |
| Withdrawn | Validation of the LiverFASt Test and the Associated Fibrosis Staging Scores Compared to Liver Tissue Pathology NCT03980912 | Fibronostics USA, Inc | — |
| Terminated | Study of the Safety and Tolerability of AXA1957 in Adolescent Subjects With Non-Alcoholic Fatty Liver Disease NCT04073407 | Axcella Health, Inc | N/A |
| Completed | The Study of Lithogenesis Processes in Patients With Non-alcoholic Fatty Liver Disease (NAFLD) NCT06357052 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabeti NCT05521633 | King Edward Medical University | Phase 3 |
| Completed | A Phase 2 Study of Elobixibat in Adults With NAFLD or NASH NCT04006145 | Albireo | Phase 2 |
| Unknown | Lifestyle Modification Programme for HIV-infected Individuals With Fatty Liver NCT03913351 | Chinese University of Hong Kong | N/A |
| Terminated | The Role of Microbiome Reprogramming on Liver Fat Accumulation NCT03914495 | AdventHealth Translational Research Institute | N/A |
| Active Not Recruiting | DIAbetes and NAFLD NCT06315361 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Treating PCOS With Semaglutide vs Active Lifestyle Intervention NCT03919929 | University of Colorado, Denver | Phase 2 / Phase 3 |
| Completed | Bariatric Surgery-Induced Shift in Gut Microbiome and NAFLD NCT04263376 | The Cleveland Clinic | — |
| Unknown | Prevalence of NAFLD and Correlation With Its Main Risk Factors Among Egyptian NCT04081571 | Cairo University | — |
| Completed | NAFLD in Diabetes Type 2 in Primary Care NCT03864510 | Linkoeping University | — |
| Active Not Recruiting | Prevalence of NAFLD in T2DM Patients NCT06445335 | Ziekenhuis Oost-Limburg | N/A |
| Completed | Safety, Tolerability, and Efficacy of Saroglitazar Mg 4 mg in Liver Transplant Recipients With Nonalcoholic Fa NCT03639623 | Zydus Therapeutics Inc. | Phase 2 |
| Completed | Genetic-specific Effects of Fructose on Liver Lipogenesis NCT03783195 | University of North Carolina, Chapel Hill | N/A |
| Unknown | Omega-3 vs Very Low Calorie Diet for Liver Size Reduction NCT03132662 | McMaster University | N/A |
| Unknown | Fighting Fatty Liver in India NCT03844165 | University of Nottingham | N/A |
| Completed | Study of the Safety and Tolerability of AXA1125 and AXA1957 in Subjects With Non-Alcoholic Fatty Liver Disease NCT04073368 | Axcella Health, Inc | N/A |
| Completed | A Self Selected Population Study of Undiagnosed NAFLD and NASH, Using an Echosens FibroScan, in at Risk Popula NCT03726827 | Fatty liver Foundation | — |
| Completed | Splanchnic and Systemic VLDL-TG and FFA Balance NCT04292977 | University of Aarhus | — |
| Completed | A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM) NCT03656744 | HighTide Biopharma Pty Ltd | Phase 2 |
| Completed | French Cohort for the Study of Non-invasive Tests of Liver Lesions in NAFLD/NASH (FreSH Cohort) NCT03695796 | University Hospital, Angers | N/A |
| Completed | A Study of Multiple Doses of HM15211(Efocipegtrutide) in Obese Subjects With NAFLD NCT03744182 | Hanmi Pharmaceutical Company Limited | Phase 1 |
| Completed | Dietary Intervention for Low Free Sugars in Children With Non-alcoholic Fatty Liver Disease NCT06579729 | China Medical University, China | N/A |
| Unknown | Prevalence, Incidence and Characteristics of NAFLD/NASH in Type 1 Diabetes Mellitus NCT04664036 | University Hospital, Antwerp | — |
| Unknown | Use of Shear Wave Elastography to Assess Non-alcoholic Fatty Liver Disease (NAFLD) NCT03587298 | RWTH Aachen University | — |
| Completed | An Investigational Study to Evaluate Experimental Medication BMS-986036 in Participants With Different Levels NCT03674476 | Bristol-Myers Squibb | Phase 1 |
| Completed | Impact of a Specific Micronutrient-probiotic-supplement on Fatty Liver of Patients After Mini-Gastric Bypass S NCT03585413 | Bonn Education Association for Dietetics r.A., Cologne, Germany | Phase 3 |
| Completed | Effect of Obesity on Proton Pump Inhibitors NCT04248335 | Children's Mercy Hospital Kansas City | Phase 4 |
| Unknown | Copeptin and Nonalcoholic Fatty Liver Disease NCT03254563 | University of Colorado, Denver | — |
| Terminated | RCT of Caloric Restriction vs. Alternate-Day Fasting in Non-Alcoholic Fatty Liver Disease NCT03365531 | University of Florida | N/A |
| Completed | Investigation of Microbiome-based Prognostical Biomarkers in Patients With Morbid Obesity and Bariatric Surger NCT03391401 | St. Franziskus Hospital | — |
| Completed | YMCA Diabetes Prevention Program for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) NCT03512184 | Weill Medical College of Cornell University | N/A |
| Completed | Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fat NCT03371355 | Akcea Therapeutics | Phase 2 |
| Completed | HOMA-IR as a Screening Test in NAFLD NCT04084925 | Fayoum University | — |
| Withdrawn | Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM NCT03291249 | Tiziana Life Sciences LTD | Phase 2 |
| Unknown | Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: the Correlation Analysis and Risk Prediction Mode NCT03534908 | Wuhan University | — |
| Completed | Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan NCT03289897 | Perspectum | N/A |
| Completed | Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease NCT03261739 | Bird Rock Bio, Inc. | Phase 1 |
| Completed | Augmenting Growth Hormone to Ameliorate Nonalcoholic Fatty Liver Disease in Adolescents NCT02726542 | Massachusetts General Hospital | EARLY_Phase 1 |
| Completed | Treatment of NAFLD With Two Different Diets NCT03118310 | Karolinska University Hospital | Phase 2 |
| Completed | Effects of a Portfolio Diet on NAFLD in Type 2 Diabetic Patients NCT03380416 | Federico II University | N/A |
| Completed | Hydroxytyrosol and Vitamin E in Pediatric NASH NCT02842567 | Bambino Gesù Hospital and Research Institute | Phase 3 |
| Completed | Dietary Supplementation With Butyrate in Individuals With Liver Steatosis and Metabolic Syndrome NCT06398522 | University of Bologna | N/A |
| Unknown | Effects of Dietary Nutrients on Liver and Adipose Tissue Metabolism NCT03090347 | University of Oxford | N/A |
| Unknown | Effects of Short-term Interventions for a Healthy Lifestyle on the Human Lipidome in Subjects With Metabolic S NCT03047655 | German Institute of Human Nutrition | N/A |
| Completed | Measurement of Alanine Aminotransaminase (ALT) Following Initiation of Antidiabetic Agents in Patients With Ty NCT03233178 | LMC Diabetes & Endocrinology Ltd. | — |
| Completed | The Effect of a High-fat vs. High-sugar Diet on Liver Fat Accumulation and Metabolism NCT03145350 | University of Oxford | N/A |
| Completed | Healthy Eating Through Reduction Of Excess Sugar NCT02948647 | University of Southern California | N/A |
| Unknown | The Effect of Empagliflozin on NAFLD in Asian Patients With Type 2 Diabetes NCT02964715 | University of Malaya | Phase 4 |
| Unknown | Effects of Tomato Products in Children With NAFLD NCT03463967 | Federico II University | N/A |
| Completed | Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver NCT02927184 | Viking Therapeutics, Inc. | Phase 2 |
| Completed | Polyunsaturated Fatty Acids in Patients With NAFLD. NCT02647294 | General University Hospital, Prague | N/A |
| Completed | The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study) NCT02663544 | Fred Hutchinson Cancer Center | N/A |
| Unknown | Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis NCT02051842 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | Phase 4 |
| Withdrawn | Cost Effective Non Invasive Diagnostic Modalities and Predictive Model for Development and Progression of Fibr NCT02658786 | Institute of Liver and Biliary Sciences, India | — |
| Completed | The Effect Of NS-0200 Versus Placebo On Hepatic Fat Content In Patients With Non Alcoholic Fatty Liver Disease NCT02546609 | NuSirt Biopharma | Phase 2 |
| Completed | CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial NCT02654977 | University of Michigan | Phase 2 |
| Recruiting | Biomarkers in the Diagnosis and Prognosis of NAFLD NCT06098417 | University of Trieste | — |
| Completed | Non-alcoholic Fatty Liver Disease in Women With Polycystic Ovary Syndrome NCT05843955 | Hacettepe University | — |
| Completed | Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adoles NCT02216552 | University of Manitoba | Phase 2 / Phase 3 |
| Unknown | Ernährungs-Interventions-Fettleber-Studie (Interventional Study on Nutritional Effects on NAFLD) NCT02458586 | German Institute of Human Nutrition | N/A |
| Recruiting | The European NAFLD Registry NCT04442334 | Newcastle University | — |
| Completed | Effect of Probiotic Co-administration With Omega-3 Fatty Acids on NAFLD NCT03528707 | Bogomolets National Medical University | N/A |
| Unknown | Diet and Physical Activity on NAFLD and Erytrocyte Membrane Lipid Profile. NCT02347696 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Completed | The Impact of Bariatric Surgery on Non-alcoholic Fatty Liver Disease NCT02828579 | Jagiellonian University | — |
| Completed | Dietary Determinants in Patients With Nonalcoholic Fatty Liver Disease (NAFLD) NCT02649049 | National Nutrition and Food Technology Institute | — |
| Completed | Resolution of Liver Fat in Non-alcoholic Fatty Liver Disease NCT02558530 | Helsinki University Central Hospital | N/A |
| Unknown | Probiotics in the Treatment of NAFLD NCT02764047 | Federal University of Health Science of Porto Alegre | N/A |
| Completed | Impact of Weight Loss Surgery in Adolescents With NAFLD NCT02952170 | Massachusetts General Hospital | N/A |
| Completed | Sleeve Gastrectomy in Adolescents With Complicated Morbid Obesity and NAFLD NCT02564679 | Bambino Gesù Hospital and Research Institute | N/A |
| Completed | Low Carbohydrate Diet: The Effects on Non Alcoholic Fatty Liver Disease in Obese Teens With Metabolic Syndrome NCT02358928 | University of Texas Southwestern Medical Center | N/A |
| Completed | Autonomic Dysfunction in Non-Alcoholic Fatty Liver Disease NCT02132780 | Virginia Commonwealth University | — |
| Completed | Response of NAFLD Patients to Mediterranean Diet NCT03203486 | Harokopio University | N/A |
| Unknown | Transient Elastography of the Liver ( Fibroscan ) and Bariatric Surgery NCT02122263 | Ziv Hospital | — |
| Unknown | Effects of Overfeeding Followed by Weight Loss on Liver Fat Content and Adipose Tissue Inflammation NCT02133144 | University of Helsinki | N/A |
| Completed | DHA and Vitamin D in Children With Biopsy-proven NAFLD NCT02098317 | Bambino Gesù Hospital and Research Institute | Phase 3 |
| Unknown | Treatment of Non Alcoholic Fatty Liver Disease With Lifestyle Modification and Acupuncture NCT02006329 | Ziv Hospital | N/A |
| Withdrawn | ER Stress in NAFLD NCT01807910 | Vanderbilt University | EARLY_Phase 1 |
| Unknown | Probiotics and Microbiota in Bariatric Surgery NCT01922830 | Tel-Aviv Sourasky Medical Center | N/A |
| Unknown | Diabetes Nutrition Algorithms in Patients With Overt Diabetes Mellitus NCT02459496 | German Institute of Human Nutrition | N/A |
| Completed | Understanding the Role of Dietary Fatty Acids on Liver Fat Metabolism in Humans NCT01936779 | University of Oxford | N/A |
| Unknown | Diabetes Nutrition Algorithm - Prediabetes NCT02609243 | German Institute of Human Nutrition | N/A |
| Completed | Study of Losartan in the Treatment of NAFLD in Children NCT01913470 | Miriam Vos, MD | Phase 2 |
| Unknown | POLY-unsaturated Fatty Acids in the Preservation of Dietary Effects on Hepatosteatosis and Energy Metabolism i NCT03047668 | German Institute of Human Nutrition | N/A |
| Completed | Effect of Physical Activity on NAFLD NCT02367742 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Unknown | C1q/TNF-related Proteins in Non-Alcoholic Fatty Liver Disease NCT02083159 | Korea University | — |
| Recruiting | Liver Damage and Cardiometabolic Disorders in NAFLD NCT04036357 | University of Roma La Sapienza | — |
| Terminated | Rifaximin in Fatty Liver Disease NCT01355575 | Imperial College London | Phase 4 |
| Completed | Effect of Mediterranean Diet on Non-alcoholic Fatty Liver Disease NCT01798719 | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | N/A |
| Completed | Non-alcoholic Fatty Liver Disease and Its Treatment NCT05480007 | Shanghai 10th People's Hospital | N/A |
| Unknown | Prediction of Severity of Liver Disease Non Alcoholic Fatty Liver Disease in Patients With Suspected NAFLD by NCT01281059 | Hadassah Medical Organization | N/A |
| Recruiting | Integrated Multi-omics Data for Personalized Treatment of Obesity-associated Fatty Liver Disease NCT05554224 | Institut Investigacio Sanitaria Pere Virgili | — |
| Recruiting | Reversal of Lipid-Induced Insulin Resistance NCT02193295 | Yale University | N/A |