NCT06579729

Dietary Intervention for Low Free Sugars in Children With Non-alcoholic Fatty Liver Disease

Dietary Intervention for Low Free Sugars in Children With Non-alcoholic Fatty Liver Disease: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 146 (actual)
• Sponsor: China Medical University, China · Academic / Other
• Sex: All
• Age: 5 Years – 14 Years
• Healthy volunteers: Not accepted

Summary

A 48-week dietary intervention program was conducted in children aged 5-14 years with a diagnosis of NAFLD, who were randomized into a low free sugar diet group and a regular diet group. The primary objective of this study is to determine whether a low free sugar dietary intervention program improves liver function, fasting glucose, fasting insulin, lipid profile and hepatic steatosis in children with NAFLD. The effects of the intervention will be analyzed and compared at weeks 12, 24 and 48.

Conditions

• NAFLD
• Low-free Sugar Dietary
• Child Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Dietary intervention for low free sugars	After baseline data collection, the intervention group received a 30-60 minute educational session with a dietitian and clinicians, including a health education prescription. Interventions occurred at weeks 1, 12 and 24, with routine evaluations of disease, diet, physical activity, and adherence. Follow-ups at 48 weeks assessed NAFLD extent, dietary profile, and health knowledge for both subjects and guardians.

Timeline

• Start date: 2018-10-01
• Primary completion: 2022-04-01
• Completion: 2022-04-01
• First posted: 2024-08-30
• Last updated: 2024-08-30

Locations

1 site across 1 country: China