NCT03380416

Effects of a Portfolio Diet on NAFLD in Type 2 Diabetic Patients

Medium-term Effects of a Portfolio Diet on Non-alcoholic Fatty Liver Disease in Type 2 Diabetic Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: Federico II University · Academic / Other
• Sex: All
• Age: 35 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Patients with type 2 diabetes and non-alcoholic fatty liver disease will be enrolled. According to a parallel design, the participants will be randomized to a Portfolio diet or a monounsaturated fatty acid (MUFA)-rich diet (used as control) for 8 weeks. At the beginning and at the end of the trial, the participants will undergo a MRI spectroscopy to evaluate fatty liver content. Moreover, the participants will undergo a test meal resembling the nutritional composition of the assigned diet to evaluate fasting and postprandial metabolic response.

Conditions

• Diabetes Type 2
• NAFLD

Interventions

Type	Name	Description
OTHER	Portfolio Diet	Medium-term (8 weeks ) nutritional intervention
OTHER	MUFA Diet	Medium-term (8 weeks ) nutritional intervention used as control

Timeline

• Start date: 2017-04-04
• Primary completion: 2019-03-07
• Completion: 2019-12-20
• First posted: 2017-12-21
• Last updated: 2020-03-03

Locations

1 site across 1 country: Italy