Trials / Completed
CompletedNCT03118310
Treatment of NAFLD With Two Different Diets
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 74 (actual)
- Sponsor
- Karolinska University Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The impact of popular diets on liver-related health is unclear. In this randomized, controlled trial, patients with NAFLD will be randomized to one of two popular diets or a placebo diet.
Detailed description
Subjects will include patients with MRI-verified NAFLD, with no concurrent liver diseases. Randomization will be done to either a control diet, the 5:2 diet or a low-carb-high-fat diet. The subjects will follow the diet for three months, after which a new MRI is performed. Main outcomes measure is reduction in liver fat.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | 5:2 diet | Dietary intervention according to 5:2 diet during three months. |
| BEHAVIORAL | LCHF | Dietary intervention according to LCHF diet during three months. |
| BEHAVIORAL | Placebo diet | Placebo diet: normal dietary advice |
Timeline
- Start date
- 2017-04-06
- Primary completion
- 2020-08-31
- Completion
- 2020-08-31
- First posted
- 2017-04-18
- Last updated
- 2020-09-02
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT03118310. Inclusion in this directory is not an endorsement.