NCT02459496

Diabetes Nutrition Algorithms in Patients With Overt Diabetes Mellitus

Dietary Strategies to Improve Metabolism and Body Weight in Type 2 Diabetes

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: German Institute of Human Nutrition · Academic / Other
• Sex: All
• Age: 18 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

Basic treatment of type 2 diabetes should focus on diet, physical activity and lifestyle. Nevertheless, in early and late stage of T2DM, lifestyle intervention is mostly substituted by pharmacological intervention, although lifestyle modification and dietary treatment would be favourable. The researchers therefore investigate dietary strategies such as low-carb and very-low calory diets regarding their potential to improve metabolism and body weight in (mostly) long-term T2DM patients.

Detailed description

Basic treatment of type 2 diabetes should focus on diet, physical activity and lifestyle. Nevertheless, in early and late stage of T2DM, lifestyle intervention is mostly substituted by pharmacological intervention, although lifestyle modification and dietary treatment would be favourable. The researchers therefore investigate dietary strategies such as low-carb diets and very-low calory diets regarding their potential to improve metabolism and body weight in (mostly) long-term T2DM patients. An intensive intervention of 3 weeks is followed by an 11-month maintenance phase to consolidate metabolic improvements.

Conditions

• Type 2 Diabetes
• NAFLD
• Obesity
• Dyslipoproteinaemia
• Hypertension

Interventions

Type	Name	Description
BEHAVIORAL	dietary consulting and advise	first phase: 3 weeks of very-low calory diet (low-carb or normo-carb) second phase: 49 weeks of eucaloric diet under DGE guidelines

Timeline

• Start date: 2013-09-01
• Primary completion: 2020-12-01
• Completion: 2020-12-01
• First posted: 2015-06-02
• Last updated: 2020-06-24

Locations

2 sites across 1 country: Germany