NCT04235855

EUS Guided Liver Biopsy - Will it Give Better Yield, More Tissue With Less Complication?

EUS Guided Liver Biopsy Proposal Titled : EUS Guided Liver Biopsy - Will it Give Better Yield , More Tissue With Less Complication ?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Asian Institute of Gastroenterology, India · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Liver biopsy would be done by Endoscopic Ultrasound using Acquire needle.

Detailed description

In this study, we aim to evaluate the tissue adequacy of EUS guided liver biopsy for parenchymal liver disease and to evaluate if diagnostic yield of left lobe is non-inferior to right lobe biopsies and to assess if combination biopsies have better yield than single lobe biopsies. Safety of the procedure and technical success would be noted. The data would be analysed using SPSS software and needful variables and tests would be used as per statistical requirement.

Conditions

• NAFLD
• Alcoholic Hepatitis

Interventions

Type	Name	Description
DEVICE	Endoscopic USG guided Liver biopsy	Diagnostic yield with EUS guided liver biopsy - Left lobe Bx vs combined right and left lobe or vs right lobe would be assessed.
DEVICE	Percutaneous Liver Biopsy	All liver biopsies done in the Institute as routine procedure by percutaneous route would be compared with the EUS guided biopsy in respect to safety , tissue quality and diagnostic yield .

Timeline

• Start date: 2019-10-31
• Primary completion: 2022-01-01
• Completion: 2022-01-01
• First posted: 2020-01-22
• Last updated: 2022-01-04

Locations

1 site across 1 country: India