| Not Yet Recruiting | Continuous Remote Vital Sign Monitoring During Labour Analgesia With Remifentanil NCT07167498 | Nordsjaellands Hospital | — |
| Not Yet Recruiting | Effectiveness of Sacral Massage on Labor Pain, Depression, Stress, and Anxiety NCT07501598 | University of Basrah | N/A |
| Not Yet Recruiting | Induction of Labor by Cervical Ripening and Transcutaneous Electrical Nerve Stimulation (TENS) NCT07494539 | HOT Noémie | N/A |
| Withdrawn | Intracervical Balloon Placement With Nitrous Oxide Administration NCT06498908 | Olivia Sher | Phase 3 |
| Recruiting | Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor. NCT07401147 | Ricardo A Gutierrez Ramirez, MD, MSc, FACOG | N/A |
| Recruiting | Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor NCT07440069 | Universidad Nacional Autonoma de Honduras | Phase 4 |
| Recruiting | Left Lateral Position vs Supine Position to Reduce Active Labor Duration NCT07411352 | Universidad Nacional Autonoma de Honduras | N/A |
| Not Yet Recruiting | Sacral Pressure During Labor: Effects on Pain and Maternal Satisfaction NCT07371039 | Izmir Kavram Vocational School | N/A |
| Completed | Dural Puncture Epidural vs Standard Epidural Analgesia in Labor NCT07278895 | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | N/A |
| Not Yet Recruiting | Effect of Multi-Sensory Interventions on Labor Pain, Comfort, and Birth Satisfaction NCT07248787 | Ataturk University | N/A |
| Enrolling By Invitation | Exploring the Effect of Aromatherapy NCT07155876 | Baptist Health South Florida | N/A |
| Completed | Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia NCT07145775 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | Music Therapy for Labor Pain and Anxiety NCT07139574 | University Tunis El Manar | N/A |
| Completed | The Effect of Progressive Relaxation Exercise NCT07090902 | Karabuk University | N/A |
| Recruiting | Comparing PIEB and CEI for Labor Pain Relief NCT07395934 | Da Nang Family General Hospital | N/A |
| Enrolling By Invitation | Determining the Effect of the ThetaHealing Meditation Method Given During the Antenatal Period on Labor Pain a NCT07267351 | Near East University, Turkey | — |
| Not Yet Recruiting | Sacral Massage With a Tennis Ball on Labor Pain and Comfort During the Intrapartum Period NCT06898580 | Istanbul University - Cerrahpasa | N/A |
| Completed | Nada Yoga Music Therapy for Pain and Anxiety in Labor NCT07392112 | Sinop University | N/A |
| Enrolling By Invitation | Virtual Reality for Pain and Anxiety Relief in Labor NCT07194967 | University Tunis El Manar | N/A |
| Completed | Epidural vs. Dural Puncture Epidural in Labor Analgesia NCT06849726 | Medipol University | N/A |
| Active Not Recruiting | Exploring the Optimal Concentration of Lidocaine Test Dose for Labor Analgesia NCT06819579 | The Second Affiliated Hospital of Chongqing Medical University | N/A |
| Recruiting | Effects of Pilates Ball and Sacral Massage Applications on Labor Pain, Labor Duration and Childbirth Satisfact NCT06927531 | Ege University | N/A |
| Completed | Stress Ball Intervention During Active Labor NCT07451834 | KTO Karatay University | N/A |
| Not Yet Recruiting | Comparison of Dural Puncture Epidural Versus Conventional Epidural for Labour Analgesia in Primigravida NCT06766812 | Sohag University | N/A |
| Not Yet Recruiting | The Effect of Su-jok Therapy Applied in the First Stage of Labor on Pain Level in Primiparas NCT06760013 | Hitit University | N/A |
| Active Not Recruiting | Effect of Peanut Ball Use ın Prımarıes on Labor Paın, Duratıon of Labor Anxıety and NCT06804577 | Ayşe FİLİZ | N/A |
| Recruiting | The Effect of Musıc on Labor Paın, Anxıety and Breastfeedıng Success NCT06621238 | Ataturk University | N/A |
| Not Yet Recruiting | Parturient Satisfaction With Epidural Analgesia by PCEA or Manual Boluses NCT06094946 | Women's Hospital HUS | — |
| Recruiting | Stress Ball Used in the Active Phase of Labor on Labor Pain and Birth Comfort NCT06626958 | Ataturk University | N/A |
| Recruiting | Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural NCT06572241 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Recruiting | Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural An NCT06655675 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | The Effect of Continuous Midwifery-led Care in Birth Management NCT06660615 | Istanbul University - Cerrahpasa | N/A |
| Withdrawn | Evaluation and Management of Parturients' Pain Intensity NCT04662450 | Harvard Medical School (HMS and HSDM) | N/A |
| Not Yet Recruiting | The Effect of Pregnant-controlled Sacral Massage on Mothers' Labor Pain, Perception, Process and Midwives' Sat NCT06499402 | Osmaniye Korkut Ata University | N/A |
| Recruiting | Pain Management With Virtual Reality Hypnosis NCT06502457 | Centre Hospitalier Universitaire, Amiens | N/A |
| Not Yet Recruiting | The Effect of LI4 Acupressure on Perineal Pain and Postpartum Comfort During Episiotomy Repair NCT06407505 | Uskudar University | N/A |
| Enrolling By Invitation | The Influence of Oxytocin on Intrapartum Fetal Well-being and Delivery Outcomes in Patients Receiving Epidural NCT06403982 | Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland | N/A |
| Unknown | Neuraxial Ultrasound Device Study NCT06281249 | Stanford University | N/A |
| Unknown | Randomized Controlled Trial of Combined Lidocaine - Chlorprocaine in Labor Epidural Analgesia. NCT06302257 | Hadassah Medical Organization | Phase 4 |
| Completed | Programmed Intermittent Epidural Bolus (PIEB) Techniques for Labour Analgesia NCT06266767 | Hamad Medical Corporation | Phase 4 |
| Unknown | Alexander Technique on Labor Pain and Anxiety NCT06263894 | Marmara University | N/A |
| Active Not Recruiting | The Effect of Foot Reflexology Massage on the Perception of Labor Pain in Nulliparous Pregnant Women NCT07045675 | Atlas University | — |
| Recruiting | Effects of Rosa Damascena and Frankincense Essential Oils in Labor NCT06189794 | Balikesir University | N/A |
| Unknown | The Effect of Diverting Attention Technique on Labor Pain and Satisfaction NCT06194890 | Hitit University | N/A |
| Recruiting | ED90 of Bupivacaine After Lidocaine Test Dose with DPE and EPL NCT06146842 | Brigham and Women's Hospital | Phase 4 |
| Completed | Focusing on the Maryam's Flower During the Birth NCT06128759 | Ondokuz Mayıs University | N/A |
| Unknown | LOTUS Trial: Lumbar Ultrasound in Obstetric Patients With BMI > 40 NCT06305260 | MetroHealth Medical Center | N/A |
| Completed | Neurolinguistic Programming on Labor Pain NCT06070779 | Aysegul Kilicli | N/A |
| Unknown | Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia NCT06036797 | Maternal and Child Health Hospital of Hubei Province | Phase 2 |
| Completed | The Effect of Virtual Reality Glasses Application on Labor Pain and Comfort in Multiparous Pregnants NCT07013227 | Marmara University | N/A |
| Unknown | Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia. NCT05898737 | Centre Hospitalier Universitaire Saint Pierre | — |
| Completed | Assessment of Sensory Block During Labour Epidural Analgesia in Patients Experiencing Pain During First Stage NCT05881395 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Recruiting | Dexmedetomidine for Intermittent Epidural Boluses Versus Continuous Epidural Infusion for Labour Epidural Anal NCT05781854 | Assiut University | Phase 2 / Phase 3 |
| Unknown | The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain NCT05759364 | Western Galilee Hospital-Nahariya | N/A |
| Completed | Influence of Immersion in Water During Labor on the Request of Epidural Anesthesia by Pregnant Women NCT06036277 | Centre Hospitalier Universitaire de Saint Etienne | — |
| Completed | Dexmedetomidine vs Fentanyl in Controlling Labor Pain NCT06392321 | Al-Azhar University | N/A |
| Unknown | Analgesic Additives to Epidural Bupivacaine in Normal Labor NCT05746351 | Assiut University | N/A |
| Completed | The Effect of Guided Imagery and Music Play on Labor Pain, Anxiety, and Birth Experience NCT06035172 | Istanbul University - Cerrahpasa | N/A |
| Unknown | Gender of Anesthesiologist and Time to Labor Epidural NCT05744570 | Umeå University | — |
| Completed | The Effect of Continuous Midwifery Care at Birth on Labor Pain, Comfort and Satisfaction NCT05520060 | Cukurova University | N/A |
| Completed | Color Doppler to Confirm Epidural Catheter Positioning in Parturient NCT05606952 | Menoufia University | N/A |
| Completed | Comparative Study of the Loading Dose Administrated Via Epidural Needle or Epidural Catheter for Labor Analges NCT05594771 | Women's Hospital School Of Medicine Zhejiang University | N/A |
| Recruiting | Fetal Assessment of the Myocardium and Evaluation of the Neonate NCT06186973 | Oslo University Hospital | — |
| Completed | The Effect of Massage and Acupressure on Labor Pain NCT06057116 | Near East University, Turkey | N/A |
| Completed | Dexmedetomidine As An Adjuvant To Bupivacaine 0.1% in Labor Analgesia NCT06550414 | Services Institute of Medical Sciences, Pakistan | N/A |
| Recruiting | Neuraxial Labor Analgesia and Offspring Neurodevelopment NCT04964206 | Dong-Xin Wang | — |
| Completed | Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida NCT06304311 | University of Lahore | N/A |
| Unknown | ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia NCT05543694 | Brigham and Women's Hospital | Phase 4 |
| Unknown | Outcome of Combined Tramadol and Paracetamol Versus Pentazocine as Labour Analgesia Among Parturients NCT05565274 | Federal Medical Centre, Yenagoa | N/A |
| Completed | Showering During Labor NCT05529823 | Sakarya University | N/A |
| Completed | Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural An NCT05512065 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Epidural Tap in Labor Analgesia FOR LABOR ANALGESIA NCT05499234 | Medipol University | N/A |
| Completed | Characteristics of the Tsui Test and Pressure Waveform to Confirm Epidural Catheter Placement in Parturients W NCT05361512 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Completed | Agreement Between Laterality of Tsui Test and Laterality of Color Flow Doppler Signals During Labor Epidural A NCT05281991 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Completed | The Effect of Acupressure on Labor Pain and Anxiety Levels During Labor in Primiparas Women NCT05411289 | Cairo University | N/A |
| Completed | Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia NCT05901441 | Maternal and Child Health Hospital of Hubei Province | Phase 2 |
| Completed | Virtual Reality Animation and Ice Massage on The Hoku Point NCT05850624 | Kastamonu University | N/A |
| Completed | The Effect of Massage and Musıc Therapy on Birth Pain, Posttravmatic Comfort and Posttraumatic Development NCT05317052 | Amasya University | N/A |
| Completed | Alternative Method: Chewing Gum in Labor NCT06959940 | Biruni University | N/A |
| Unknown | Effect of Intrapartum Continuous Midwife Support on Maternal and Neonatal Stress Level NCT05302401 | Marmara University | N/A |
| Completed | The Effect of Nutrition and Fluid Intake in the First Stage of Labor NCT06547177 | Hilal Yuvacı | N/A |
| Completed | Sacral Spread of Sensory Block After Dural Puncture Epidural Technique Compared With Epidural for Labour Analg NCT05217134 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Completed | Spinal Analgesia as Fast Track Painless Labor NCT05271760 | Prince Sattam Bin Abdulaziz University | — |
| Completed | Effect of Virtual Reality for Pain Management During Intracervical Balloon Placement for Artificial Childbirth NCT05155826 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | The Effect of Labor Diet During the Delivery Process NCT07058168 | Biruni University | N/A |
| Completed | The Effect of the Multifunctional Birthing Ball on Labor Pain NCT06229808 | Near East University, Turkey | N/A |
| Unknown | The Effect of Music Therapy on Labour Pain, Anxiety, and Analgesia NCT05149677 | The University of The West Indies | N/A |
| Completed | Differential Sensory Block During Labor Epidural Analgesia: a Prospective Observational Study to Investigate t NCT05187962 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Completed | Ice Massage Applied to SP6 Point at Labor NCT05676879 | Balikesir University | N/A |
| Completed | The Effect of Electro-fetal monıtorısıon Sound on Anxiety, paın and Postpartum Bonding at the First Phase of D NCT06271889 | Saglik Bilimleri Universitesi | N/A |
| Completed | Optimum Length of Catheter in the Epidural Space for Labor Analgesia in Non-obese Women: a Randomised Controll NCT04946032 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Comparing Effectiveness of CSE Versus DPE for Labor Analgesia NCT05068661 | Duke University | Phase 4 |
| Completed | Assessment of Catheter Flow Direction Using Color Flow Doppler in Labor Epidurals NCT05126745 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Recruiting | The Stimulation To Induce Mothers Study NCT05079841 | Yale University | Phase 4 |
| Completed | Effects of Massage With Peppermint Oil on Labor Pain NCT05136066 | Ankara City Hospital Bilkent | N/A |
| Completed | VR Scenario for Labor Pain Control NCT05879848 | Federico II University | N/A |
| Completed | The Effect of Birth Ball Exercise on Labor Pain, Delivery Duration, Birth Comfort, and Birth Satisfaction NCT05711472 | Selcuk University | N/A |
| Completed | The Effect of Clove Oil on Labor Pain NCT05130957 | Ankara City Hospital Bilkent | N/A |
| Unknown | A Comparison Between 2 Methods of Local Anesthetic Administration for Maintaining Labor Analgesia After Dural NCT05034211 | Aretaieio Hospital | N/A |
| Completed | Epidural Dexmedetomidine vs Nalbuphine for Labor Analgesia NCT05327088 | Ain Shams University | Phase 2 |
| Completed | Labor Induction and Pain Relief With Paracetamol Versus Placebo NCT05097950 | Western Galilee Hospital-Nahariya | N/A |
| Completed | Transcutaneous Electrical Nerve Stimulation for Labor Pain Control in Combination With Cardiotocography NCT04946838 | Aalborg University | N/A |
| Completed | The Effect of Using a Birth Ball and Squatting Position During Labor NCT05360823 | Fatma Dünmez | N/A |
| Completed | Virtual Reality, Labor Pain, Anxiety, Birth Perception NCT05495009 | Abant Izzet Baysal University | N/A |
| Unknown | Investigating the Effect of Virtual Reality on Labour Analgesia Use NCT04992663 | Zuyderland Medisch Centrum | N/A |
| Completed | Effect of Epidural Analgesia on Labour, Neonatal and Maternal Outcomes. NCT05579808 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Unknown | A Study on the Effect of Position on Walking Labour Epidural Efficacy NCT04469101 | University of Saskatchewan | N/A |
| Completed | The Effectiveness of the Applications Made in Line With the Algorithm for Coping With Labor Pain NCT04883047 | Gazi University | N/A |
| Completed | The Effect of Chewing Gum and Use of Stress Balls on Perception of Labor Pain, Fear of Birth, and Duration of NCT05380258 | Kastamonu University | N/A |
| Completed | Use of Standardized Algorithm for the Management of Epidural Analgesia for Labor and Delivery NCT04814199 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Unknown | Use of Virtual Reality in Active Labor NCT04862039 | Federico II University | N/A |
| Completed | Spinal Fentanyl or Epidural Analgesia in the Early First Phase of Induced Labor NCT04645823 | Women's Hospital HUS | Phase 4 |
| Completed | Stimulation Therapy for Inducing Mothers NCT04756089 | Yale University | N/A |
| Completed | Effect of Different Labour Analgesics on Maternal and Fetal Blood Flow Observed by Doppler Ultrasonography NCT06099938 | First Affiliated Hospital of Jinan University | — |
| Completed | Virtual Reality to Reduce Labor Pain NCT05167383 | Clinique Saint-Jean, Bruxelles | N/A |
| Completed | Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques NCT04814537 | Brigham and Women's Hospital | Phase 4 |
| Completed | Virtual Reality Compared to Nitrous Oxide for Labor Analgesia NCT04749043 | Brendan Carvalho | N/A |
| Completed | Lower Limb Compression Prevents Hypotension After Epidural in Labor NCT04750486 | Wayne State University | N/A |
| Completed | Changes in Sensory Block Level During a Programmed Intermittent Epidural Bolus Regimen for Labor Analgesia: an NCT04716660 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | — |
| Completed | Birthing Ball (Peanut Ball) Positions NCT04729426 | Gonca Karataş Baran | N/A |
| Completed | Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia NCT04728048 | Ciusss de L'Est de l'Île de Montréal | N/A |
| Completed | The Effect Of Lavender Essential Oil On Birth Pain NCT05169138 | Near East University, Turkey | N/A |
| Unknown | Effect of Music in Labor in Women Who Underwent Induction of Labor NCT04662424 | Federico II University | N/A |
| Completed | Immersive Virtual Reality Satisfies the Women in Labor by Distracting Them From Their Labor Pain in Labor on L NCT05032456 | Bahçeşehir University | N/A |
| Withdrawn | Effect of Epidural Analgesia During Labor on Force of Maternal Push NCT04888858 | Henry Ford Health System | Phase 4 |
| Completed | The Effects of Breathing Exercises and Virtual Reality Applications During Pregnancy and Labor. NCT05527236 | Semra Çevik, phD | N/A |
| Recruiting | Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During La NCT04011150 | KK Women's and Children's Hospital | Phase 3 |
| Completed | Virtual Reality, Experience During Labour; a Qualitative Research (VIREL) NCT04858984 | Zuyderland Medisch Centrum | N/A |
| Completed | Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth. NCT06429111 | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | — |
| Completed | Virtual Reality Effect on Labor Pain and Satisfaction NCT05280327 | Inonu University | N/A |
| Completed | The Effect of External Pressure Applı̇ed to the Palm on Labor Paı̇n and Childbirth Experı̇ence NCT06106867 | Istanbul University - Cerrahpasa | N/A |
| Withdrawn | To Study the Association Among Labor Pain and Physical Parameters in Laboring Pregnant Women NCT04207138 | National Taiwan University Hospital | — |
| Completed | To Study the Association Among Labor Pain and Physical Parameters in Laboring Pregnant Women NCT04461704 | CJshine Technology Company Ltd. | — |
| Completed | Heat Application to the Sacral Region and Pain Level During the First Stage of Labor NCT06297031 | Istanbul Demiroglu Bilim University | N/A |
| Completed | Effect of Using a Birth Ball on Birth Satisfaction and Pain in Pregnant Women During Labor NCT05312502 | Selcuk University | N/A |
| Unknown | Intrathecal Analgesia for Normal Labour NCT04221568 | Assiut University | Phase 1 |
| Unknown | Comparison of Epidural, Combined and Dural Puncture Labor Epidural on Pain, and Course of Vaginal Delivery NCT04290702 | University of Athens | N/A |
| Completed | The Effect of Fatima Ana's Hand on Birth Pain and Duration NCT05196841 | KTO Karatay University | N/A |
| Completed | Dural Puncture Epidural Versus Combined Spinal Epidural With Epidural Volume Extension in Labor Analgesia NCT04234178 | Ataturk University | N/A |
| Terminated | Drug Concentration and Volume on Adequate Labor Analgesia With PIEB NCT03553576 | Northwestern University | Phase 4 |
| Completed | Effectiveness of Breathing Exercises During the Second Stage of Labor NCT04556643 | Riphah International University | N/A |
| Completed | DilaCheck Cervical Dilation Measurement Trial NCT03440723 | Elm Tree Medical Inc. | N/A |
| Completed | Effectiveness of Using the Swiss Ball in Birth NCT04124835 | Instituto Materno Infantil Prof. Fernando Figueira | N/A |
| Completed | Efficacy of Peanut Ball Usage on Labor Pain, Support and Control, Anxiety, and Labor Duration NCT04204395 | Taipei Medical University | N/A |
| Completed | The Effect of Lower Back Massage on Perceived Labor Pain NCT05222867 | Eskisehir Osmangazi University | N/A |
| Unknown | The Application of Analgesia Nociception Index as an Objective Labor Pain Assessment During Epidural Analgesia NCT03975816 | Changhua Christian Hospital | — |
| Completed | Evaluation of Objective Pain Measurement Device NCT03975660 | Stanford University | N/A |
| Unknown | The Effect of Exposure to an Informative Video on Maternal Anxiety NCT04136301 | Wolfson Medical Center | N/A |
| Unknown | Comparison of Intrathecal Versus Epidural Fentanyl on Fetal Bradycardia in Labor Combined Spinal Epidural Anal NCT03623256 | Augusta University | Phase 4 |
| Terminated | Epidural Placement Using Handheld Ultrasound Device vs. Traditional Landmark Palpation NCT04020042 | University of Texas Southwestern Medical Center | N/A |
| Completed | Transcutaneous Electrical Nerve Stimulation for Labor Pain Control NCT04894539 | Aalborg University | N/A |
| Terminated | Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour NCT04011098 | University of Saskatchewan | Phase 1 |
| Unknown | Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia NCT03730753 | Université de Sherbrooke | N/A |
| Completed | Delivery Pain and Postpartum Comfort NCT04977713 | Kırklareli University | N/A |
| Completed | Fetal Life: Smart-Device Based Uterine Activity Monitoring NCT03940365 | Fetal Life LLC | N/A |
| Unknown | The Effect of Labor Dance on Traumatic Birth Perception and Comfort NCT04287699 | Selcuk University | N/A |
| Completed | Effect of Hypnobirthing Training on Fear, Pain, Satisfaction and, Birth Outcomes NCT04838340 | Aydin Adnan Menderes University | N/A |
| Completed | Focusing on Maryam's Flower at Labor NCT04393870 | Balikesir University | N/A |
| Completed | A Novel Approach to Optimize Programmed Intermittent Epidural Bolus (PIEB) Delivery for Labour Analgesia NCT03871530 | IWK Health Centre | N/A |
| Completed | Endorphin at Labor Pain and Acupressure NCT04367038 | Serap ÖZTÜRK ALTINAYAK | N/A |
| Completed | Efficacy and Safety of Intravenous Paracetamol in Manament of Labour Pain NCT04744727 | Menoufia University | N/A |
| Withdrawn | Evaluation of the Effect the Medical Team in the Delivery Room Has on Pain Management During Labor. NCT03045705 | Rambam Health Care Campus | N/A |
| Unknown | Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) Versus Placebo During the First Stage NCT03990441 | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | N/A |
| Unknown | TheEffect of pH on Misoprostol in Induction of Labor NCT03829592 | Aljazeera Hospital | N/A |
| Completed | The WE Pilot Study: Walking Epidurals NCT03710382 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Trial of Music During Labor and Delivery NCT03779386 | Federico II University | N/A |
| Completed | Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: A Sequential Allocatio NCT03735771 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Epidural Catheter Thread Between Two Different Vendors NCT03722446 | University of Michigan | N/A |
| Completed | Effects of Different Birthing Balls Used at the First Stage of Childbirth NCT04827797 | Gaziantep Islam Science and Technology University | N/A |
| Completed | Programmed Intermittent Epidural Bolus For Laboring Obstetrical Women NCT03712735 | University of British Columbia | Phase 4 |
| Completed | Effect of Hot Pack on Labor Pain, Duration of Labor, and Satisfaction of Primigravidae Women in Saudi Arabia NCT04177888 | King Saud University | N/A |
| Unknown | Comparison of Combined Spinal-epidural Analgesia Versus Epidural Analgesia for Pain Management During Labor NCT03600272 | Deng Dongrui | N/A |
| Completed | Identification of the Sensory Level Block to Cold During Epidural Analgesia for Labor: A Cohort Study to Deter NCT03572439 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Color Doppler Ultrasound to Locate Needle in Labor Epidural NCT03596333 | Augusta University | — |
| Unknown | The Association Between Epidural Labor Analgesia and Pregnancy Outcomes NCT03381495 | Deng Dongrui | N/A |
| Completed | The Effect Of Ice Massage On Perceıved Pain NCT04288388 | Selcuk University | N/A |
| Unknown | Effect of LED Photobiomodulation on Analgesia During Labor NCT03496857 | University of Nove de Julho | N/A |
| Completed | Community Based Doulas for Migrant Women in Labour and Birth in Sweden - a Randomised Controlled Trial NCT03461640 | Karolinska Institutet | N/A |
| Terminated | Virtual Reality in Labor and Delivery for Reduction in Pain NCT03437031 | Cedars-Sinai Medical Center | N/A |
| Completed | Effects of Ambulation During First Stage of Labour on Maternal and Neonatal Outcomes NCT03447015 | Mutah University | N/A |
| Completed | Effect of Labor Dance and Music on Labor Pain and Fear of Childbirth NCT03648099 | Ankara University | N/A |
| Completed | Different Spinal Needles Sizes and Dural Puncture Epidural For Labor Analgesia NCT03389945 | University of Chile | N/A |
| Unknown | Effect of Epidural Opioid Administered in the First A Period on the Progress of Labour NCT03344042 | Medical University of Warsaw | Phase 4 |
| Completed | CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens NCT03117595 | Sarah Beckley | Phase 4 |
| Completed | Combined Implementation of Dural Puncture Epidural and Programmed Intermittent Epidural Bolus for Labor Analge NCT03366935 | Shanghai First Maternity and Infant Hospital | N/A |
| Completed | Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine Sleep NCT03539562 | University of California, San Francisco | — |
| Completed | Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: Comparing 125 mL/h Ver NCT03236298 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Unknown | The Effect of Medical Clowning During Labor NCT03167567 | The Baruch Padeh Medical Center, Poriya | N/A |
| Completed | Pethidine Analgesia on Labor Duration NCT03882814 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Terminated | Epidural Fentanyl for 2nd Stage Labor Analgesia NCT03120780 | Ohio State University | Phase 4 |
| Unknown | Determination of the Optimal "Next Bolus" Interval for Programmed Intermittent Bolus Epidural Analgesia NCT03044392 | IWK Health Centre | N/A |
| Completed | THE EFFECT OF LABOR DANCE ON THE LABOR PAIN, BIRTH SATISFACTION AND NEONATAL OUTCOMES NCT04196660 | Selcuk University | N/A |
| Completed | DPE Technique in Labor Epidural for Morbidly Obese Women NCT03074695 | Duke University | Phase 4 |
| Withdrawn | Patient Controlled Remifentanil Analgesia for Normal Labour NCT04541719 | Mansoura University | Phase 2 |
| Completed | The Programmed Intermittent Epidural Bolus Adrenaline Study NCT03043781 | University Hospital, Akershus | N/A |
| Completed | Wide Use of Paperless Partograph in Evaluation of Labour NCT03276117 | Assiut University | — |
| Unknown | Intrathecal Clonidine Addiction for Combined Spinal Epidural Analgesia During Labor NCT03018171 | San Giovanni Calibita Fatebenefratelli Hospital | Phase 4 |
| Completed | Effect of Whole Body Vibration Exercises for Patients wıth Chronic Nonspeific Low Back Pain NCT04611451 | Yerkoy State Hospital | N/A |
| Completed | Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous NCT02963337 | University Medical Centre Ljubljana | — |
| Completed | CSE v. Epidural for Postpartum Depression NCT03022526 | Grace Lim, MD, MS | N/A |
| Unknown | VPIA Remifentanil for Labour Pain to Reduce Maternal Desaturation and Improve Analgesic Titration NCT02733835 | KK Women's and Children's Hospital | Phase 4 |
| Completed | Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40 NCT02984267 | Thomas J. Vernon | N/A |
| Completed | Comparison of PIEB vs CEI for Labor Analgesia NCT02949271 | Duke University | Phase 4 |
| Completed | Virtual Reality Analgesia in Labor: The VRAIL Pilot Study NCT02926469 | University of Michigan | N/A |
| Completed | Assessment of the Use of Ultrasound for Epidural Catheter Placement and Comparison With Palpation Technique NCT02271100 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour NCT02885350 | Helsinki University Central Hospital | Phase 4 |
| Completed | Pethidine Versus Nitrous Oxide for Pain Relief During Labor NCT02783508 | HaEmek Medical Center, Israel | N/A |
| Completed | Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor-3 NCT02887222 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Individualized Timing of Analgesia and Effectiveness of Labor Analgesia NCT02920489 | Peking University First Hospital | N/A |
| Completed | Music and/or Video Games During Labor NCT03024411 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | 3 Simple Questions to Predict Labor Pain and Epidural Analgesia Use in Parturients NCT02824302 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Spinal Sufentanil for Obstetric Analgesia NCT04141527 | Lund University | — |
| Unknown | Management of Postoperative Pain With Preemptive Analgesia in Cesarean Section NCT02879435 | Mark Kosanovich | N/A |
| Completed | MASSAGE AND HOT APPLICATION ON LABOR NCT04382833 | Balikesir University | N/A |
| Completed | Intermittent Ropivacaine Bolus for Epidural Labor Analgesia NCT02809742 | Pierre and Marie Curie University | — |
| Terminated | The Response Patterns to the Electrical Stimulation of Epidural Catheters With Varying Pulse Widths in Term Pr NCT02762149 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | BREATHING EXERCISES FOR LABOR PAIN AND DURATION NCT03066973 | Ataturk University | N/A |
| Completed | Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2 NCT02758405 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Failure of Vaginal Delivery After Induction NCT02758340 | Karachi Medical and Dental College | Phase 3 |
| Completed | The Effect of Sacral Massage on Labor NCT03755284 | Semra Çevik, phD | N/A |
| Completed | Labor Pain and Postpartum Behavioral Health Outcomes Study NCT02692404 | University of Pittsburgh | — |
| Completed | Effects of Yoga and Meditation on The Birth Process NCT04883541 | Uskudar University | N/A |
| Completed | Labour Pain and Birth-Specific Stereogram Cards (BSSC) NCT05386004 | Atlas University | N/A |
| Completed | Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation NCT03103100 | University of Alabama at Birmingham | Phase 3 |
| Completed | Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor NCT02550262 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Best Beginnings for Babies Birth Sister Program Evaluation NCT02550730 | Boston Medical Center | N/A |
| Unknown | Birth Ball Versus Meperidine and Haloperidol Injection for Pain Relief During First Stage of Labour NCT02493192 | Hospital General Universitario Gregorio Marañon | Phase 4 |
| Completed | A Comparison of Epidural Analgesia: Continuous Infusion Versus Programmed Intermittent Boluses NCT02510287 | Fundación Santa Fe de Bogota | N/A |
| Completed | A Comparison of Extraperitoneal Versus Transperitoneal Cesarean Section NCT02479932 | Ataturk University | N/A |
| Unknown | ANSiStim Study for Active Labor Pain NCT02427139 | DyAnsys, Inc. | N/A |
| Completed | The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia NCT02672397 | Oregon Health and Science University | N/A |
| Unknown | The Effect of Oxycodone to the Placental Circulation at Early Labour NCT02573831 | Kuopio University Hospital | Phase 4 |
| Completed | Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses NCT02340806 | Northwestern University | N/A |
| Terminated | Intermittent Automated Devices for Labor Analgesia in Emilia Romagna NCT02710877 | University of Modena and Reggio Emilia | N/A |
| Completed | Epidural Analgesia and Delivery of Second Twin NCT04608006 | Abdelrady S Ibrahim, MD | — |
| Completed | Response Patterns to the Electric Stimulation of Epidural Catheters in Term Pregnant Women NCT02274467 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia NCT02412969 | Medical University of South Carolina | N/A |
| Completed | Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain NCT01846221 | Columbia University | Phase 4 |
| Terminated | Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes NCT02121184 | Northwestern University | N/A |
| Completed | Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC) NCT02105558 | The University of Texas Health Science Center, Houston | Phase 4 |
| Completed | The Effect of Metrics Based Performance Based Progression in Provision of Labor Epidural Analgesia NCT02185079 | Cork University Hospital | N/A |
| Completed | Labour Analgesia; Comparing a Combinations of Either Fentanyl or Bupivacaine With Intrathecal Morphine NCT02498171 | Makerere University | N/A |
| Completed | Development and Validation of Metrics Lumbar Labor Epidural Catheter Placement NCT02179879 | Cork University Hospital | — |
| Completed | Intrathecal Hydromorphone for Labor Analgesia NCT01598506 | Emory University | Phase 2 |
| Completed | Epidural Volume Extension During a Combined Spinal-Epidural Technique for Labor Analgesia. NCT01810406 | IWK Health Centre | N/A |
| Completed | Pain Relief Effects on Length of Labor NCT01750099 | University of Texas Southwestern Medical Center | N/A |
| Completed | Comparison of Ultrasound Guided Low Epidural Catheter Placement With Standard Epidural Catheter Placement NCT01182220 | University of Chicago | — |
| Unknown | Oxycodone in Treatment of Early Labour Pain Efficacy and Safety NCT02575677 | Kuopio University Hospital | — |
| Unknown | The Effects of Intermittent Epidural Bolus on Fever During Labor Analgesia NCT01708668 | ShanWu Feng, M.D. | N/A |
| Withdrawn | Comparing Sedara to Butorphanol in Early Labor NCT01636999 | West Penn Allegheny Health System | N/A |
| Unknown | Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement NCT01651962 | Kai Schoenhage | Phase 4 |
| Completed | A Comparison Study of Patient Controlled Epidural Analgesia (PCEA) With and Without Basal Infusion Using Ropiv NCT02084589 | Paraskevi Matsota | N/A |
| Completed | Drotaverine to Shorten the Length of Labor NCT01639027 | Ain Shams Maternity Hospital | Phase 2 / Phase 3 |
| Completed | A Case Series of VPIA Using Remifentanil for Labour and Delivery NCT02122705 | KK Women's and Children's Hospital | — |
| Terminated | Maternal Epidural Steroids and Hyperthemia NCT02212210 | Medical University of South Carolina | EARLY_Phase 1 |
| Terminated | Inhaled Nitrous Oxide and Labor Analgesia NCT01738672 | Ya'aqov Abrams | Phase 2 |
| Completed | Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women NCT01555671 | Kanuni Sultan Suleyman Training and Research Hospital | Phase 4 |
| Unknown | Effects of Aromatherapy on Childbirth NCT01051726 | University of Nottingham | Phase 2 |
| Completed | Prophylactic Ephedrine and Combined Spinal Epidurals for Labor NCT02062801 | Sharp HealthCare | Phase 4 |
| Terminated | Intracutaneous Sterile Water Injections NCT01513447 | Northwestern University | N/A |
| Completed | Oral Paracetamol as Preemptive Analgesia for Labor Pain NCT01817829 | Ain Shams University | Phase 3 |
| Terminated | Effect of Epidural Analgesia on the Parameter ANI During Childbirth NCT01505283 | Hopital Foch | N/A |
| Completed | Analgesic Efficacy of a Multiport Versus Uniport Flexible Catheter for Labor Epidural Analgesia NCT01861821 | Baylor Research Institute | N/A |
| Completed | Prenatal Education About Reducing Labor Stress (PEARLS) NCT02327559 | University of California, San Francisco | N/A |
| Completed | Intravenous Infusion of Paracetamol for Intrapartum Analgesia of Labor NCT01428375 | Ain Shams University | Phase 3 |
| Completed | Effect of Prenatal Education on Perceptions of Epidural Acceptance NCT01709591 | Santa Clara Valley Health & Hospital System | N/A |
| Completed | The Effect of Virtual Reality Glasses on Labor Pain NCT01687933 | Mashhad University of Medical Sciences | Phase 2 / Phase 3 |
| Completed | Intranasal Fentanyl in Treatment of Labour Pain NCT02571179 | Kuopio University Hospital | Phase 4 |
| Completed | Prostin and Propess in Induction of Labor NCT01635439 | Ain Shams University | Phase 3 |
| Completed | Analgesic Effects of Intravenous Paracetamol on Labor Pain NCT01394731 | King Abdulaziz University | Phase 4 |
| Withdrawn | Cervical Capsaicin for Labor Induction and Pain Relief NCT00771511 | Columbia University | Phase 4 |
| Withdrawn | Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients? NCT01243216 | University of Missouri-Columbia | N/A |
| Completed | Effect of Hyoscine and Promethazine on Labor Pain NCT01644838 | Mashhad University of Medical Sciences | Phase 2 / Phase 3 |
| Terminated | The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia NCT01146457 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Oxycodone for Labor Pain - Pharmacokinetics (PK), Safety and Efficacy NCT01016821 | Kuopio University Hospital | N/A |
| Completed | Does Ultrasound Scanning of the Lumbar Spine Improve Patient Satisfaction and the Ease of Insertion Epidurals? NCT00996905 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Epidural Labor Analgesia and Infant Neurobehavior NCT00987441 | Nanjing Medical University | N/A |
| Terminated | Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE NCT01005459 | Wake Forest University | Phase 4 |
| Terminated | Combined Spinal/Epidural (CSE) Saline Duration/Spread NCT01062893 | Wake Forest University Health Sciences | Phase 2 |
| Withdrawn | Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor NCT00871442 | Neil Roy Connelly, MD | Phase 3 |
| Completed | Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic E NCT04887649 | Universidad Nacional de Colombia | Phase 3 |
| Completed | Ten-year Practice of Labor Pain Control in China NCT00776581 | Nanjing Medical University | — |
| Unknown | Does Having a Spouse Present During Epidural Analgesia Affect Stress Levels in the Parturient and Her Spouse? NCT00763126 | Rabin Medical Center | N/A |
| Completed | Epidural Neostigmine for Labor Pain NCT00779467 | Wake Forest University | Phase 1 |
| Completed | Effect of Doula in Nulliparas and Multiparas NCT00755092 | Nanjing Medical University | N/A |
| Completed | Intravenous Remifentanil for Labor Analgesia NCT00710086 | Nanjing Medical University | Phase 4 |
| Completed | Epidural Analgesia in Different Cervix Diameter and the Rate of Cesarean Delivery NCT00677274 | Nanjing Medical University | N/A |
| Completed | Doula Combined Latent Phrase Epidural Analgesia in Primiparous Women NCT00664118 | Nanjing Medical University | N/A |
| Unknown | fMRI Measurements on Pain Relief Methods in First Stage Labor Pain NCT00768014 | Chang Gung Memorial Hospital | — |
| Terminated | The Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes NCT00787176 | Northwestern University | N/A |
| Terminated | Optimal Regimen of Patient-controlled Epidural Analgesia in Laboring Patients NCT03566342 | Maimonides Medical Center | — |
| Completed | Usefulness of the Tsui Test in Combined Spinal-Epidural Analgesia in Labour NCT00464841 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | N/A |
| Completed | Programmed Intermittent Epidural Bolus Time Interval and Injection Volume NCT00417027 | Northwestern University | N/A |
| Completed | Epidural Analgesia Versus IV Meperidine for Labor Pain Control NCT00296751 | Rambam Health Care Campus | N/A |
| Completed | The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery NCT00443560 | Northwestern University | — |
| Completed | Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia NCT00418015 | Northwestern University | — |
| Completed | Labor Analgesia in the Latent Phrase NCT00647725 | Nanjing Medical University | N/A |
| Completed | Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery NCT00380978 | Northwestern University | N/A |
| Completed | Labor Analgesia With Ropivacaine and Clonidine NCT00626977 | UPECLIN HC FM Botucatu Unesp | — |
| Withdrawn | Epidural Fentanyl-bupivacaine Versus Clonidine-bupivacaine for Breakthrough Pain in Advanced Labor NCT00691795 | Columbia University | Phase 4 |